Patents by Inventor Gunter Ditzinger
Gunter Ditzinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230190685Abstract: The invention relates to formulations comprising a halogenated salicylanilide, or a pharmaceutically acceptable salt thereof, and a cyclodextrin. The formulations may be in the form of a liquid formulation, particularly an aqueous formulation, and provide high concentrations of solubilised halogenated salicylanilide. Also disclosed a formulations in the form of powders and aerosols. Also disclosed are the formulations for use in the treatment of bacterial and viral infections, and the treatment of inflammatory diseases. The formulations are particularly suitable for administration by inhalation for the treatment of bacterial and viral pulmonary infections and the treatment of pulmonary inflammatory diseases.Type: ApplicationFiled: March 26, 2021Publication date: June 22, 2023Inventors: Morten SOMMER, Rasmus TOFT-KEHLER, Anne Katrine TOFT-KEHLER, Günter DITZINGER, Mads JELLINGSOE, Philippe ANDRES, Matthias Manne KNOPP
-
Publication number: 20220323384Abstract: The invention relates to a method of treating a viral infection caused by or associated with SARS-CoV-2 in a subject, the method comprising administering to the subject by inhalation intraorally and/or intranasally a therapeutically effective amount of a formulation comprising niclosamide, or a pharmaceutically acceptable salt thereof, and a cyclodextrin.Type: ApplicationFiled: April 18, 2022Publication date: October 13, 2022Inventors: Morten Otto Alexander Sommer, Rasmus Toft-Kehler, Anne Katrine Toft-Kehler, Günter Ditzinger, Mads Jellingsoe, Phillippe Andres, Matthias Knopp
-
Patent number: 11324708Abstract: The invention relates to a method of treating a viral infection caused by or associated with SARS-CoV-2 in a subject, the method comprising administering to the subject by inhalation intraorally and/or intranasally a therapeutically effective amount of a formulation comprising niclosamide, or a pharmaceutically acceptable salt thereof, and a cyclodextrin.Type: GrantFiled: May 25, 2021Date of Patent: May 10, 2022Assignee: UNION therapeutics A/SInventors: Morten Otto Alexander Sommer, Rasmus Toft-Kehler, Anne Katrine Toft-Kehler, Günter Ditzinger, Mads Jellingsoe, Philippe Andres, Matthias Manne Knopp
-
Patent number: 11045434Abstract: The invention relates to a method of treating a viral infection caused by or associated with SARS-CoV-2 in a subject, the method comprising administering to the subject by inhalation intraorally and/or intranasally a therapeutically effective amount of a formulation comprising niclosamide, or a pharmaceutically acceptable salt thereof, and a cyclodextrin.Type: GrantFiled: November 13, 2020Date of Patent: June 29, 2021Assignee: UNION therapeutics A/SInventors: Morten Otto Alexander Sommer, Rasmus Toft-Kehler, Anne Katrine Toft-Kehler, Günter Ditzinger, Mads Jellingsoe, Philippe Andres, Matthias Manne Knopp
-
Publication number: 20160367488Abstract: A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.Type: ApplicationFiled: June 24, 2016Publication date: December 22, 2016Inventors: Gunter Ditzinger, Bernard Gabriel, Anne-Hortense Schmitt-Hoffmann, Lutz Wevelsiep
-
Patent number: 9399023Abstract: A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.Type: GrantFiled: June 9, 2015Date of Patent: July 26, 2016Assignee: Glaxo Group LimitedInventors: Günter Ditzinger, Bernhard Gabriel, Anne-Hortense Schmitt-Hoffmann, Lutz Wevelsiep
-
Publication number: 20150265539Abstract: A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.Type: ApplicationFiled: June 9, 2015Publication date: September 24, 2015Inventors: Günter DITZINGER, Bernhard GABRIEL, Anne-Hortense SCHMITT-HOFFMANN, Lutz WEVELSIEP
-
Patent number: 9084823Abstract: A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.Type: GrantFiled: April 14, 2011Date of Patent: July 21, 2015Assignee: Glaxo Group LimitedInventors: Günter Ditzinger, Bernhard Gabriel, Anne-Hortense Schmitt-Hoffmann, Lutz Wevelsiep
-
Patent number: 9084824Abstract: A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.Type: GrantFiled: February 27, 2014Date of Patent: July 21, 2015Assignee: Glaxo Group LimitedInventors: Günter Ditzinger, Bernhard Gabriel, Anne-Hortense Schmitt-Hoffmann, Lutz Wevelsiep
-
Publication number: 20140205661Abstract: A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.Type: ApplicationFiled: February 27, 2014Publication date: July 24, 2014Applicant: GLAXO GROUP LIMITEDInventors: Günter DITZINGER, Bernhard GABRIEL, Anne-Hortense SCHMITT-HOFFMANN, Lutz WEVELSIEP
-
Patent number: 8697122Abstract: A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.Type: GrantFiled: December 17, 2009Date of Patent: April 15, 2014Assignee: Glaxo Group LimitedInventors: Günter Ditzinger, Bernhard Gabriel, Anne-Hortense Schmitt-Hoffmann, Lutz Wevelsiep
-
Patent number: 8536208Abstract: A pharmaceutical composition for oral administration which is self-emulsifying on contact with an aqueous phase, in particular gastrointestinal fluids, and which comprises: (a) an antifungally active compound of formula (I) wherein R1, R2 and R3 are independently of one another hydrogen, F or Cl; or a pharmaceutically acceptable acid addition salt thereof, and (b) a carrier comprising a solubilizer component for the antifungally effective component (a).Type: GrantFiled: August 20, 2008Date of Patent: September 17, 2013Assignee: Basilea Pharmaceutica AGInventors: Christian Bucher, Günter Ditzinger, Estelle Dubois, Delphine Marchaud
-
Publication number: 20110281918Abstract: A pharmaceutical composition for oral administration which is self-emulsifying on contact with an aqueous phase, in particular gastrointestinal fluids, and which comprises: (a) an antifungally active compound of formula (I) wherein R1, R2 and R3 are independently of one another hydrogen, F or Cl; or a pharmaceutically acceptable acid addition salt thereof, and (b) a carrier comprising a solubilizer component for the antifungally effective component (a).Type: ApplicationFiled: August 20, 2008Publication date: November 17, 2011Inventors: Christian Bucher, Günter Ditzinger, Estelle Dubois, Delphine Marchaud
-
Publication number: 20110212170Abstract: A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.Type: ApplicationFiled: April 14, 2011Publication date: September 1, 2011Inventors: Günter Ditzinger, Bernhard Gabriel, Anne-Hortense Schmitt-Hoffmann, Lutz Wevelsiep
-
Publication number: 20100136108Abstract: A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.Type: ApplicationFiled: December 17, 2009Publication date: June 3, 2010Inventors: Günter Ditzinger, Bernhard Gabriel, Anne-Hortense Schmitt-Hoffmann, Lutz Wevelsiep
-
Publication number: 20050042278Abstract: A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.Type: ApplicationFiled: October 5, 2004Publication date: February 24, 2005Inventors: Gunter Ditzinger, Bernhard Gabriel, Anne-Hortense Schmitt-Hoffmann, Lutz Wevelsiep
-
Patent number: 5613494Abstract: Polycondensates which contain tartaric acid derivatives, processes for their preparation and use thereof.The invention relates to polycondensates which consist of at least 95 mol % of recurring structural units of the formula I ##STR1## where R.sup.1 is a 2,3-O-alkylidenetartaric acid derivative (II) or furo[2,5] (V), alkyl, alkenyl, cycloalkyl, cycloalkenyl, aryl or a heterocycle, X is --O-- --NH-- or --S-- and R.sup.2 is 2,3-O-alkylidene-L-threitol (III) or a compound of the formula VI, alkyl, alkenyl, cycloalkyl, cycloalkenyl, aryl or a heterocycle, with the proviso that more than 5 mol % of the radicals R.sup.1 and/or R.sup.2 are present in the polycondensate of the formula I, where R.sup.1 is compound of the formula II or R.sup.2 is a compound of the formula III or R.sup.1 is a compound of the formula II and R.sup.2 is a compound of the formula III, or in which more than 5 mol % of the radicals R.sup.1 and R.sup.2 are present in the polycondensate of the formula I, wherea) R.sup.Type: GrantFiled: May 4, 1995Date of Patent: March 25, 1997Assignee: Hoechst AktiengesellschaftInventors: Volker Krone, Michael Magerstadt, Axel Walch, Gunter Ditzinger, Norbert Lill
-
Patent number: 5565423Abstract: Cyclopeptides and their use as absorption promoters when applied to the mucosaThe invention relates to a compound of the formula I ##STR1## or a physiologically tolerated salt thereof, in which X is a basic L- or D-amino acid,Y is a neutral or basic L- or D-amino acid,Z is a neutral or basic L- or D-amino acid, which can be identical to or different from Y,R.sup.1 is an N-bonded acyl radical of the formula II ##STR2## in which Ar is a phenyl radical, which is optionally substituted by 1, 2 or 3 identical or different radicals from the series comprising hydroxyl, (C.sub.1 -C.sub.4)-alkoxy, amino, carboxyl, (C.sub.1 -C.sub.4)-alkylamino and halogen, or is a 2-aminothiazol-4-yl radical,p is an integer from zero to 4 and q, n, m and 1 independently of one another are zero or 1.Type: GrantFiled: April 7, 1995Date of Patent: October 15, 1996Assignee: Hoechst AktiengesellschaftInventors: Jurgen Sandow, Walter Durckheimer, Gunter Ditzinger, Hans-Peter Merkle
-
Patent number: 5505784Abstract: The invention relates to polycondensates which consist of at least 95 mol % of recurring structural units of the formula I ##STR1## where R.sup.1 is a 2,3-O-alkylidenetartaric acid derivative (II) or furo[2,5] (V), alkyl, alkenyl, cycloalkyl, cycloalkenyl, aryl or a heterocycle, X is --O--, --NH-- or --S-- and R.sup.2 is 2,3-O-alkylidene-L-threitol (III) or a compound of the formula VI, alkyl, alkenyl, cycloalkyl, cycloalkenyl, aryl or a heterocycle, with the proviso that more than 5 mol % of the radicals R.sup.1 and/or R.sup.2 are present in the polycondensate of the formula I, where R.sup.1 is compound of the formula II or R.sup.2 is a compound of the formula III or R.sup.1 is a compound of the formula II and R.sup.2 is a compound of the formula III, or in which more than 5 mol % of the radicals R.sup.1 and R.sup.2 are present in the polycondensate of the formula I, wherea) R.sup.1 is a compound of the formula V and R.sup.2 is a compound of the formula VI, orb) R.sup.Type: GrantFiled: January 10, 1995Date of Patent: April 9, 1996Assignee: Hoechst AktiengesellschaftInventors: Volker Krone, Michael Magerstadt, Axel Walch, Gunter Ditzinger, Norbert Lill
-
Patent number: 5391696Abstract: Polycondensates which contain tartaric acid derivatives, processes for their preparation and use thereof.The invention relates to polycondensates which consist of at least 95 mol % of recurring structural units of the formula I ##STR1## where R.sup.1 is a 2,3-O-alkylidenetartaric acid derivative (II) or furo[2,5] (V), alkyl, alkenyl, cycloalkyl, cycloalkenyl, aryl or a heterocycle, X is --O--, --NH-- or --S-- and R.sup.2 is 2,3-O-alkylidene-L-threitol (III) or a compound of the formula VI, alkyl, alkenyl, cycloalkyl, cycloalkenyl, aryl or a heterocycle, with the proviso that more than 5 mol % of the radicals R.sup.1 and/or R.sup.2 are present in the polycondensate of the formula I, where R.sup.1 is compound of the formula II or R.sup.2 is a compound of the formula III or R.sup.1 is a compound of the formula II and R.sup.2 is a compound of the formula III, or in which more than 5 mol % of the radicals R.sup.1 and R.sup.2 are present in the polycondensate of the formula I, wherea) R.sup.Type: GrantFiled: May 21, 1992Date of Patent: February 21, 1995Assignee: Hoechst AktiengesellschaftInventors: Volker Krone, Michael Magerstadt, Axel Walch, Gunter Ditzinger, Norbert Lill