Patents by Inventor Gunter Neef

Gunter Neef has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of trans-deca hydronaphthalene derivatives
    Patent number: 4077996
    Abstract: A process for the preparation of trans-decahydronaphthalene compounds of Formula I ##STR1## wherein X is lower alkyl, --(CH.sub.2).sub.3 --Z--R.sub.2, ##STR2## --(CH.sub.2).sub.3 COOR.sub.4, or --(CH.sub.2).sub.3 CN; Y and Z are ketalized carbonyl or free, esterified, or etherified hydroxymethylene;U is halogen;R.sub.1, r.sub.2, and R.sub.3 are lower alkyl; andR.sub.4 is alkyl;Wherein an octahydronaphthalene compound of Formula II ##STR3## is converted, in the presence of bases, by reaction of a trialkyl chlorosilane of the formula(R.sub.5).sub.3 Si--Clwherein the R.sub.5 each are lower alkyl group, to a hexahydronaphthalene compound of the formula ##STR4## The hexahydronaphthalene compound is hydrogenated, in an inert solvent with hydrogen in the presence of a platinum-, palladium-, or rhodium-containing hydrogenation catalyst, to an octahydronaphthalene compound of the formula ##STR5## and a vinyl ketone of the formulaXCOCH.dbd.CH.sub.
    Type: Grant
    Filed: April 14, 1976
    Date of Patent: March 7, 1978
    Assignee: Schering Aktiengesellschaft
    Inventors: Gerhard Sauer, Ulrich Eder, Gregor Haffer, Gunter Neef, Rudolf Wiechert
  • D-Homo-19-norsteroids
    Patent number: 4057561
    Abstract: D-homosteroids of the formula ##STR1## WHEREIN R.sup.3.alpha. is hydrogen, R.sup.3.beta. is hydroxy, lower alkanoyloxy or aroyloxy and R.sup.3.alpha. and R.sup.3.beta. taken together are oxo; R.sup.17a.alpha. is hydrogen, lower alkyl, ethynyl, vinyl, allyl, methallyl, propadienyl, 1-propynyl, butadiynyl or chloroethynyl; R.sup.17a.beta. is hydrogen, alkanoyl, aroyl, lower alkyl, cycloalkyl-lower-alkyl, benzyl, furfuryl or tetrahydropyranyl; R.sup.18 is hydrogen or methyl and the dotted line in the C-ring denotes an additional carbon to carbon bond in the 11,12-position andProcesses for the preparation thereof are disclosed.The D-homosteroids of the present invention are useful as ovulation inhibitors and androgenic/anabolic agents.
    Type: Grant
    Filed: February 22, 1977
    Date of Patent: November 8, 1977
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Andor Furst, Jurg Gutzwiller, Marcel Muller, Rudolf Wiechert, Ulrich Eder, Gunter Neef
  • Process for the preparation of 13.beta.-alkyl-4-gonene-3,17-diones
    Patent number: 4024166
    Abstract: Novel process for the preparation of 13.beta.-alkyl-4-gonene-3,17-diones of the formula ##STR1## wherein R.sub.1 is methyl or ethyl, consists of REACTING A 7A.beta.
    Type: Grant
    Filed: October 10, 1975
    Date of Patent: May 17, 1977
    Assignee: Schering Aktiengesellschaft
    Inventors: Gerhard Sauer, Ulrich Eder, Gregor Haffer, Gunter Neef, Rudolf Wiechert