Patents by Inventor Gunther Kruger

Gunther Kruger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 14-Functionalized 8,19-oxido steroids and processes for preparation thereof
    Patent number: 4134891
    Abstract: There are provided novel 14-functionalized 8,19-oxido steroids possessing 14.alpha. or 14.beta.-hydroxy, 14.alpha. and 14.beta.-acetoxy, 14.alpha.,15.alpha.-oxido or 14.beta.,15.beta.-oxido groups or a double bond in position 14 as well as processes for preparing such compounds. These compounds can be readily converted into the corresponding 14.beta.-hydroxycardenolides, 19-oxygenated cardenolides, 19-norcardenolides and unsaturated cardenolides.
    Type: Grant
    Filed: August 2, 1976
    Date of Patent: January 16, 1979
    Assignee: Steele Chemicals Co. Ltd.
    Inventor: Gunther Kruger
  • 14 .beta.-Hydroxy 3-deoxycardenolides
    Patent number: 4102884
    Abstract: Novel compounds of the formula ##STR1## useful as pharmaceutical compounds are disclosed. Processes are also disclosed for their preparation.
    Type: Grant
    Filed: May 5, 1976
    Date of Patent: July 25, 1978
    Assignee: Steele Chemicals Co. Ltd.
    Inventor: Gunther Kruger
  • 19,8-Lactone steroid derivatives and processes of preparation thereof
    Patent number: 4102883
    Abstract: There are provided novel 19,8-lactone and lactol steroids derivatives having the formula ##STR1## wherein A and B represent 14- or 15-carbon atoms, respectively, which are either linked by a double bond, or which carry an .alpha.- or .beta.-oxido or a 14.alpha.- or .beta.-hydroxy group in which case B is a methylene group; Y is .dbd.O; 3.alpha. or 3.beta.-OH;.sup.2 H;.sup.3 H; O-alkyl; or O-acyl; H; R' is OH, .dbd.O or acetoxy, the 5-hydrogen atom is either in the .alpha. or .beta.-position; there is an optional double bond in position 4(5); 5(6) and 6(7); and R is selected from the group consisting of O-acyl; ##STR2## AND CN, wherein alkyl is tetrahydropyranyl, lower alkyl, preferably methyl or ethyl, or a substituted methyl wherein the substituent is selected from the group consisting of phenyl, halogen, preferably chlorine and bromine, methoxy, CH.sub.2 .dbd.CH and HC.tbd.
    Type: Grant
    Filed: July 9, 1976
    Date of Patent: July 25, 1978
    Assignee: Steele Chemicals Co. Ltd.
    Inventor: Gunther Kruger
  • Steroid compounds and processes thereof
    Patent number: 4097477
    Abstract: Novel steroids of the formula ##STR1## Also there are provided processes for preparing such compounds. The new compounds are useful as intermediates in the preparation of known cardenolides; various of the compounds have other uses as blocking agents.
    Type: Grant
    Filed: July 9, 1976
    Date of Patent: June 27, 1978
    Assignee: Steele Chemicals Co. Ltd.
    Inventor: Gunther Kruger
  • 14,19-Dioxygenated steroid compounds and their 14-dehydro analogs and process for the preparation thereof
    Patent number: 4096142
    Abstract: There are provided novel 14,19-dioxygenated steroid compounds and their 14-dehydro analogs, as well as processes for preparing such compounds. The above compounds are useful as intermediates in the preparation of other steroids, which in turn, may be converted into valuable pharmaceutical agents.
    Type: Grant
    Filed: August 30, 1976
    Date of Patent: June 20, 1978
    Assignee: Steele Chemicals Co. Ltd.
    Inventor: Gunther Kruger
  • 4,6,8(14)-Triene steroids
    Patent number: 4058539
    Abstract: There are provided novel 4,6,8(14)-triene-steroids as well as processes for preparing such compounds. The above compounds are useful as intermediates in the preparation of other steroids, which in turn, may be converted into valuable pharmaceutical agents.
    Type: Grant
    Filed: June 16, 1976
    Date of Patent: November 15, 1977
    Assignee: Steele Chemicals Co. Ltd.
    Inventor: Gunther Kruger