Patents by Inventor Gunther Lametschwandtner

Gunther Lametschwandtner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SiRNA against Cbl-b and optionally IL-2 and IL-12 for use in the treatment of cancer
    Patent number: 9186373
    Abstract: The invention relates to a method for the immune activation of NK cells by the reduction or inhibition of the Cbl-b function in said cells. This stimulates the congenital immune system and thus permits the therapy of appropriate diseases.
    Type: Grant
    Filed: December 27, 2011
    Date of Patent: November 17, 2015
    Assignee: Apeiron Biologics AG
    Inventors: Günther Lametschwandtner, Hans Loibner, Manfred Schuster, Isabella Haslinger, Sandra Seidl
  • SIRNA AGAINST CBL-B AND OPTIONALLY IL-2 AND IL-12 FOR USE IN THE TREATMENT OF CANCER
    Publication number: 20150313931
    Abstract: The invention relates to a method for the immune activation of NK cells by the reduction or inhibition of the Cbl-b function in said cells. This stimulates the congenital immune system and thus permits the therapy of appropriate diseases.
    Type: Application
    Filed: July 16, 2015
    Publication date: November 5, 2015
    Applicant: APEIRON BIOLOGICS AG
    Inventors: Gunther Lametschwandtner, Hans Loibner, Manfred Schuster, Isabella Haslinger, Sandra Seidl
  • Method for increasing immunoreactivity
    Patent number: 8809288
    Abstract: The invention relates to an in vitro or ex vivo method for increasing the immunoreactivity of cells of the immune system, which were contacted with an antigen, said method comprising the reduction or inhibition of the Cbl-b function of said cells, thereby increasing the immunoreactivity of the cells towards the antigen.
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: August 19, 2014
    Assignees: Medizinische Universitat Innsbruck, Apeiron Biologics AG
    Inventors: Gottfried Baier, Hans Loibner, Manfred Schuster, Gunther Lametschwandtner, Dominik Wolf
  • SIRNA AGAINST CBL-B AND OPTIONALLY IL-2 AND IL-12 FOR USE IN THE TREATMENT OF CANCER
    Publication number: 20140010781
    Abstract: The invention relates to a method for the immune activation of NK cells by the reduction or inhibition of the Cbl-b function in said cells. This stimulates the congenital immune system and thus permits the therapy of appropriate diseases.
    Type: Application
    Filed: December 27, 2011
    Publication date: January 9, 2014
    Applicant: APEIRON BIOLOGICS AG
    Inventors: Günther Lametschwandtner, Hans Loibner, Manfred Schuster, Isabella Haslinger, Sandra Seidl
  • Method for Determining the Cbl-b Expression
    Publication number: 20120040864
    Abstract: The present invention relates to methods of determining intracellular Cbl-b protein in cells of a sample, comprising introducing an antibody, which binds Cbl-b intracellularly, into a cell, allowing contracting of the antibody and Cbl-b protein potentially present in the cell, detecting binding events between the antibody and Cbl-b, quantifying the detected binding events, whereby the content of Cbl-b protein is determined.
    Type: Application
    Filed: April 14, 2010
    Publication date: February 16, 2012
    Applicants: MEDIZINISCHE UNIVERSITAET INNSBRUCK, APEIRON BIOLOGICS AG
    Inventors: Hans Loibner, Gottfried Baier, Gunther Lametschwandtner, Manfred Schuster, Thomas Gruber, Dominik Wolf
  • Method for Increasing Immunoreactivity
    Publication number: 20100260808
    Abstract: The invention relates to an in vitro or ex vivo method for increasing the immunoreactivity of cells of the immune system, which were contacted with an antigen, said method comprising the reduction or inhibition of the Cbl-b function of said cells, thereby increasing the immunoreactivity of the cells towards the antigen.
    Type: Application
    Filed: December 10, 2008
    Publication date: October 14, 2010
    Applicants: MEDIZINISCHE UNIVERSITAT INNSBRUCK, APEIRON BIOLOGICS AG
    Inventors: Gottfried Baier, Hans Loibner, Manfred Schuster, Gunther Lametschwandtner, Dominik Wolf
  • Receptor In Dendritic Cells
    Publication number: 20090317827
    Abstract: The present invention provides the use of GPR91 as a target in dendritic cells.
    Type: Application
    Filed: May 2, 2006
    Publication date: December 24, 2009
    Applicant: NOVARTIS AG
    Inventors: José M. Carballido Herrera, Günther Lametschwandtner, Gudrun Werner, Antal Rot
  • GPR18 as a Biomaker for TH1 Mediated Immune Response
    Publication number: 20090208997
    Abstract: The present invention provides the use of GPR18 in diseases or disorders mediated by Th1 cell activation.
    Type: Application
    Filed: May 2, 2006
    Publication date: August 20, 2009
    Inventors: José M. Carballido Herrera, Claudia Guenther, Günther Lametschwandtner, Gudrun Werner