Patents by Inventor Gunther Thomas

Gunther Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8826903
    Abstract: In the heat utilization installation (1) according to the invention several heat sources (2) are included which are provided each with a jet pump (16), (17), (18), (19). The heat sources (2) are connected to a heat carrier circuit system (7) which includes a single, central circulating pump or circulating pump unit (20). The individual jet pumps (16) to (19) are so controlled for the respective heat sources (2), the required operating temperatures with respect to temperature difference between the outlet and inlet and the flow volume are maintained or achieved. With the possibility of independent control of the flow volumes at the various heat sources (2), uniform fluid temperatures as required for a buffer store (22) or heat consumers can be maintained.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: September 9, 2014
    Assignee: Helmut Bälz GmbH
    Inventor: Hans Günther Thoma
  • Publication number: 20110203576
    Abstract: In the heat utilization installation (1) according to the invention several heat sources (2) are included which are provided each with a jet pump (16), (17), (18), (19). The heat sources (2) are connected to a heat carrier circuit system (7) which includes a single, central circulating pump or circulating pump unit (20). The individual jet pumps (16) to (19) are so controlled for the respective heat sources (2), the required operating temperatures with respect to temperature difference between the outlet and inlet and the flow volume are maintained or achieved. With the possibility of independent control of the flow volumes at the various heat sources (2), uniform fluid temperatures as required for a buffer store (22) or heat consumers can be maintained.
    Type: Application
    Filed: February 16, 2011
    Publication date: August 25, 2011
    Inventor: Hans Günther Thoma
  • Patent number: 5344944
    Abstract: Circulation-active dihydropyridines of the formula ##STR1## in which R.sup.1 is H, CN, NO.sub.2 or --COOR.sup.7,R.sup.7 is H, alkyl or various other radicals,R.sup.2 and R.sup.4 each independently is alkyl or other radicals,R.sup.3 is H or optionally substituted alkyl, andR.sup.5 completes a keto or ester group,and physiologically acceptable salts thereof.
    Type: Grant
    Filed: September 3, 1993
    Date of Patent: September 6, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerhard Franckowiak, Albrecht Marhold, Martin Bechem, Rainer Gross, Michael Kayser, Matthias Schramm, Gunther Thomas
  • Patent number: 5162338
    Abstract: 4 Aminoaryldihydropyridines of the formula ##STR1## in which R.sup.1 is hydrogen or an organic radical, preferably methyl or ethyl,R.sup.2 is hydrogen, C.sub.1 -C.sub.5 - alkyl, --CN, --NH.sub.2, --CH.sub.2 or --CH.sub.2 OH, preferably methyl,R.sup.3 is hydrogen or alkyl, preferably hydrogen,Y is --CO-- or --SO.sub.2 --, andR.sup.4 is an organic radical, orY-R.sup.4 is hydrogen,and physiologically acceptable salts thereof, are circulation-active and effective for improving myocardial contractility, for raising blood pressure, for lowering blood sugar, for reducing mucosal swelling and for controlling the salt and fluid balance.
    Type: Grant
    Filed: October 18, 1991
    Date of Patent: November 10, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Siegfried Goldmann, Matthias Schramm, Rainer Gross, Gunther Thomas, Martin Bechem, Michael Kayser
  • Patent number: 4898865
    Abstract: Circulation active nitrodihydropyridines of the formula ##STR1## in which R represents aryl which has 6 to 12 carbon atoms and can be substituted up to 4 times, identically or differently, by halogen, nitro, cyano, alkyl, alkoxy, alkylthio, in each case having up to 6 carbon atoms, trifluoromethyl, trifluoromethoxy, difluoromethoxy, trifluoromethylthio, difluoromethylenedioxy, trifluoroethylenedioxy or tetrafluoroethylenedioxy or by benzyl, benzyloxy or benzylthio, each of which is optionally substituted by halogen, nitro, cyano, trifuoromethyl, alkyl having up to 4 carbon atoms or alkoxy having up to 4 carbon atoms, or represents a heterocycle which is optionally substituted by halogen, phenyl or alkyl having up to 4 carbon atoms and is from the group consisting of pyrryl, thienyl, furyl, pyrazolyl, imidazolyl, oxazolyl, thiazolyl, pyridyl, pyrimidyl, pyridazinyl, quinolyl, benzoxadiazolyl, chromenyl or thiochromenyl, andn represents a number from 1 to 12,and physiologically acceptable salts thereof.
    Type: Grant
    Filed: July 13, 1988
    Date of Patent: February 6, 1990
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerhard Franckowiak, Martin Bechem, Michael Kayser, Rainer Gross, Matthias Schramm, Friedel Seuter, Elisabeth Perzborn, Gunther Thomas
  • Patent number: 4886816
    Abstract: Circulation-active dihydropyridines of the formula ##STR1## in which R.sup.1 is H, CN, NO.sub.2 or --COOR.sup.7,R.sup.7 is H, alkyl or various other radicals,R.sup.2 and R.sup.4 each independently is alkyl or other radicals,R.sup.3 is H or optionally substituted alkyl,R.sup.5 completes a keto or ester group, andR.sup.6 is a direct bond or --CF.sub.2 -- or --CHF--,and physiologically acceptable salts thereof.
    Type: Grant
    Filed: May 5, 1988
    Date of Patent: December 12, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerhard Franckowiak, Albrecht Marhold, Martin Bechem, Rainer Gross, Michael Kayser, Matthias Schramm, Gunther Thomas
  • Patent number: 4876255
    Abstract: For the control of coronary diseases and thromboses there are provided the novel compounds ##STR1## in which R.sup.1 is an optionally substituted phenyl or heterocyclic radical,R.sup.2 is a cyano, keto, carboxy, ester or amide group, andX is from 0 to 6,and physiologically acceptable salts thereof.
    Type: Grant
    Filed: April 7, 1988
    Date of Patent: October 24, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerhard Franckowiak, Ulrich Rosentreter, Elisabeth Perzborn, Friedel Seuter, Michael Kayser, Gunther Thomas
  • Patent number: 4876254
    Abstract: For the treatment of circulation disorders, the novel 5-nitro-1,4-dihydropyridines of the formula ##STR1## in which R represents C.sub.6 -C.sub.14 -aryl which can be mono- to pentasubstituted by identical or different substituents from the series comprising halogen, nitro, cyano, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkoxy, C.sub.1 -C.sub.6 -alkoxy, C.sub.1 -C.sub.6 -alkylthio, trifluoromethyl, trifluoromethoxy, difluoromethoxy, trifluoromethylthio and benzyl, benzyloxy or benzylthio optionally substituted by nitro, cyano, trifluoromethyl, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxy, orrepresents a heterocycle from the series pyrryl, thienyl, furyl, pyrazolyl, imidazolyl, oxazolyl, thiazolyl, pyridyl, pyridazinyl, pyrimidyl, quinolyl, benzoxadiazolyl, chromenyl or thiochromenyl optionally mono- to tetrasubstituted by halogen, phenyl or C.sub.1 -C.sub.4 -alkyl orrepresents straight-chain, branched or cyclic alkyl with up to 14 carbon atoms,and their physiologically acceptable salts.
    Type: Grant
    Filed: April 8, 1988
    Date of Patent: October 24, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerhard Franckowiak, Michael Kayser, Matthias Schramm, Gunther Thomas, Rainer Gross, elisabeth Perzborn, Friedel Seuter
  • Patent number: 4804667
    Abstract: 4 Aminoaryldihydropyridines of the formula ##STR1## in which R.sup.1 is hydrogen or an organic radical, preferably methyl or ethyl,R.sup.2 is hydrogen, C.sub.1 -C.sub.5 -alkyl, --CN, --NH.sub.2, --CH.sub.2 or --CH.sub.2 OH, preferably methyl,R.sup.3 is hydrogen or alkyl, preferably hydrogen,Y is --CO-- or --SO.sub.2 --, andR.sup.4 is an organic radical, orY--R.sup.4 is hydrogen,and physiologically acceptable salts thereof, are circulation-active and effective for improving myocardial contractility, for raising blood pressure, for lowering blood sugar, for reducing mucosal swelling and for controlling the salt and fluid balance.
    Type: Grant
    Filed: December 22, 1986
    Date of Patent: February 14, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Siegfried Goldmann, Matthias Schramm, Rainer Gross, Gunther Thomas, Martin Bechem, Michael Kayser
  • Patent number: 4769375
    Abstract: Circulation-active dihydropyridines of the formula ##STR1## in which R.sup.1 is optionally substituted aryl or heterocyclic,R.sup.2 is H, NO.sub.2, CN, C.sub.1 -C.sub.8 -alkylsulphonyl, aryl or carboalkoxy,R.sup.3 is alkyl or aryl,R.sup.4 is H or alkyl,X is C.dbd.O or a direct bond, andn is a number from 1 to 20,or physiologically acceptable salts thereof. A synthesis using morpholines or thiomorpholines is also disclosed.
    Type: Grant
    Filed: July 25, 1986
    Date of Patent: September 6, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Horst Meyer, Gerhard Franckowiak, Gunther Thomas, Matthias Schramm, Michael Kayser, Martin Bechem, Rainer Gross
  • Patent number: 4753936
    Abstract: 1,4-Dihydropyridine-3-carboxylic acid piperazides of the formula ##STR1## in which R.sup.1 is CN or alkyl, preferably methyl,R.sup.2 is H, CN, NO.sub.2 or preferably carboxyalkyl,R.sup.3 is aryl or heterocyclic, andR.sup.4 is alkyl, cycloalkyl, aryl or an acyl radical,and physiologically acceptable salts thereof, are circulation active. Novel intermediates are also provided.
    Type: Grant
    Filed: January 12, 1987
    Date of Patent: June 28, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerhard Franckowiak, Gunther Thomas, Matthias Schramm, Michael Kayser, Rainer Gross, Martin Bechem