Abstract: A stator of an electromechanical transducer includes a winding system and a cooling system designed for through-flow of a cooling medium and including a nozzle through which the cooling medium flows during operation, such that the cooling medium flows out as an accelerated jet downstream of the nozzle. The nozzle is oriented such that part of the winding system is struck by the accelerated jet from the nozzle. A core includes cutouts for at least partial arrangement of winding sections of the winding system. The core includes a magnetically permeable body designed to include at least a first body and a second body which are arranged axially next to one another, with the first body being arranged in spaced-apart relationship from the second body to define an axial gap there between, with the cooling medium being combined in the axial gap from various flow paths guided in a parallel fashion.

Abstract: An electric machine includes a housing, a stator, a rotor which is rotatably mounted in a receiving area of the stator, a cooling device for discharging heat out of the housing, a heat exchanger which can be supplied with cooling air and which is arranged on the housing and is coupled to the cooling device, a cooling air channel, and a fan for introducing cooling air into the cooling air channel. The fan has a fan wheel rotatably mounted in a fan housing between two opposing air inlet openings of the fan housing. At least some regions of one of the two air inlet openings have a nozzle-type configuration. An air outlet opening is arranged in a radial direction of the fan wheel.

Abstract: An electrical machine includes housing surrounding a stator laminated core and a stator winding. Stator core support rings are arranged between the housing and the stator laminated core and radially surround the stator laminated core, with a cavity being formed between the housing, the stator laminated core and the stator core support rings. The stator laminated core has a cooling channel which is fluidically coupled with the cavity via a channel entry arranged centrally in the middle of the stator laminated core, thereby creating in conjunction with the channel entry a T-shaped form of the cooling channel so that a stream of coolant is not heated over an entire length of the stator laminated core, but only over a shorter stretch as a result of the T-shaped form.

Abstract: An electrical machine includes housing surrounding a stator laminated core and a stator winding. Stator core support rings are arranged between the housing and the stator laminated core and radially surround the stator laminated core, with a cavity being formed between the housing, the stator laminated core and the stator core support rings. The stator laminated core has a cooling channel which is fluidically coupled with the cavity via a channel entry arranged centrally in the middle of the stator laminated core, thereby creating in conjunction with the channel entry a T-shaped form of the cooling channel so that a stream of coolant is not heated over an entire length of the stator laminated core, but only over a shorter stretch as a result of the T-shaped form.

Abstract: A stator arrangement for an electrical machine includes a casing element as one component and at least two stator segments, which are arranged in the casing element as further components. One of the components has a feather key groove and another one of the components has a feather key, which corresponds with the feather key groove, for bracing the one component against the other component.

Abstract: A stator arrangement for an electrical machine includes a casing element as one component and at least two stator segments, which are arranged in the casing element as further components. One of the components has a feather key groove and another one of the components has a feather key, which corresponds with the feather key groove, for bracing the one component against the other component.

Abstract: The present invention is directed to methods and assays for identifying subjects participating in clinical trials that may exhibit a placebo response and identifying treatments for subjects with varying degrees of placebo responses. In one aspect, a method of selecting subjects to participate in a clinical trial is disclosed. In another aspect, methods for treating a subject and determining a treatment dosage are disclosed. In an exemplary embodiment, a method for determining a response to a treatment of a subject having, suspected of having, or at risk for developing a disorder, such as cardiovascular disorder, irritable bowel syndrome, diabetes, autoimmune disorders, inflammation, neurological disorders, chronic pain, cancer, cancer treatments, allergies, depression, migraines, addiction, obesity, and other disorders, syndromes, or diseases, is disclosed.

Abstract: The present invention is directed to methods and assays for identifying subjects participating in clinical trials that may exhibit a placebo response and identifying treatments for subjects with varying degrees of placebo responses. In one aspect, a method of selecting subjects to participate in a clinical trial is disclosed. In another aspect, methods for treating a subject and determining a treatment dosage are disclosed. In an exemplary embodiment, a method for determining a response to a treatment of a subject having, suspected of having, or at risk for developing a disorder, such as cardiovascular disorder, irritable bowel syndrome, diabetes, autoimmune disorders, inflammation, neurological disorders, chronic pain, cancer, cancer treatments, allergies, depression, migraines, addiction, obesity, and other disorders, syndromes, or diseases, is disclosed.

Abstract: A dynamo-electric machine, in particular a multi-pole dynamo-electric machine includes a shaft and an integrated fan which is connected to the shaft by a friction-wheel planetary gear. The friction-wheel planetary gear has first and second rolling bearings, with the first rolling bearing having an outer ring mounted in the hub of the fan, and the second rolling bearing having an outer ring which is press-fitted in the hub of the fan. Arranged between the first and second rolling bearings is a driving bush for transmitting a rotational speed of the shaft onto balls of the second bearing to thereby increase a rotational speed of the fan by a predefined factor compared to the rotational speed of the shaft.

Abstract: The present invention provides methods of treating inflammatory diseases/disorders in a subject by inhibiting/antagonizing TREM-1 expression/activity/signal transduction and/or DAP12/TyroBP expression and/or activity. Methods of detecting the presence of inflammatory disease in a subject by detecting TREM-1 and/or DAP12/TyroBP expression and/or activity in the subject or a sample obtained therefrom, wherein increased expression or activity is indicative of the inflammatory disease are also included. The present invention further provides methods for assessing the efficacy of a TREM-1-modulating agent administered to a patient by detecting levels of secreted phosphoprotein 1 (SPP1) and/or one or more other biomarkers in the patient or in a sample from the patient.