Patents by Inventor Guo-Hua Chu

Guo-Hua Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spirocyclic heterocyclic derivatives and methods of their use
    Patent number: 7563802
    Abstract: Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the ? opioid receptor and may be useful, inter alia, for treating and/or preventing pain, anxiety, gastrointestinal disorders, and other ? opioid receptor-mediated conditions.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: July 21, 2009
    Assignee: Adolor Corporation
    Inventors: Roland E. Dolle, Bertrand Le Bourdonnec, Christopher W. Ajello, Minghua Gu, Guo-Hua Chu, Paul Anson Tuthill, Sr., Lara K. Leister, Q. Jean Zhou
  • Spirocyclic Heterocyclic Derivatives And Methods Of Their Use
    Publication number: 20080102031
    Abstract: Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the ? opioid receptor and may be useful, inter alia, for treating and/or preventing pain, anxiety, gastrointestinal disorders, and other ? opioid receptor-mediated conditions.
    Type: Application
    Filed: December 20, 2007
    Publication date: May 1, 2008
    Applicant: Adolor Corporation
    Inventors: Roland Dolle, Bertrand Le Bourdonnec, Christopher Ajello, Minghua Gu, Guo-Hua Chu, Paul Tuthill, Lara Leister, Q. Zhou
  • SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE
    Publication number: 20070269374
    Abstract: Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the ?-opioid receptor and may be useful, inter alia, for treating and/or preventing pain, anxiety, gastrointestinal disorders, and other ?-opioid receptor-mediated diseases, disorders, and/or conditions.
    Type: Application
    Filed: April 4, 2007
    Publication date: November 22, 2007
    Inventors: Roland Dolle, Bertrand Le Bourdonnec, Guo-Hua Chu
  • Amide derivatives and methods of their use
    Patent number: 7160902
    Abstract: Amide derivatives of the general formulae Ia and Ib: are disclosed. Pharmaceutical compositions containing these compounds, and methods for their use, inter alia, for treating and/or preventing gastrointestinal disorders, pain, and pruritus are also disclosed.
    Type: Grant
    Filed: November 14, 2003
    Date of Patent: January 9, 2007
    Assignee: Adolor Corporation
    Inventors: Roland E. Dolle, Guo-Hua Chu, Minghua Gu
  • Spirocyclic heterocyclic derivatives and methods of their use
    Publication number: 20060270695
    Abstract: Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the ? opioid receptor and may be useful, inter alia, for treating and/or preventing pain, anxiety, gastrointestinal disorders, and other ? opioid receptor-mediated conditions.
    Type: Application
    Filed: March 30, 2006
    Publication date: November 30, 2006
    Inventors: Roland Dolle, Bertrand Le Bourdonnec, Guo-Hua Chu
  • Fused bicyclic carboxamide derivatives and methods of their use
    Patent number: 7034051
    Abstract: Fused bicyclic carboxamide derivatives are disclosed. Pharmaceutical compositions containing the compounds and methods for their use are also disclosed.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: April 25, 2006
    Assignee: Adolor Corporation
    Inventors: Roland E. Dolle, Guo-Hua Chu
  • Spirocyclic heterocyclic derivatives and methods of their use
    Publication number: 20050159438
    Abstract: Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the ? opioid receptor and may be useful, inter alia, for treating and/or preventing pain, anxiety, gastrointestinal disorders, and other ? opioid receptor-mediated conditions.
    Type: Application
    Filed: October 1, 2004
    Publication date: July 21, 2005
    Inventors: Roland Dolle, Bertrand Le Bourdonnec, Christopher Ajello, Minghua Gu, Guo-Hua Chu, Paul Tuthill, Lara Leister, Q. Zhou
  • Amide derivatives and methods of their use
    Publication number: 20050107355
    Abstract: Amide derivatives of the general formulae Ia and Ib: are disclosed. Pharmaceutical compositions containing these compounds, and methods for their use, inter alia, for treating and/or preventing gastrointestinal disorders, pain, and pruritus are also disclosed.
    Type: Application
    Filed: November 14, 2003
    Publication date: May 19, 2005
    Inventors: Roland Dolle, Guo-Hua Chu, Minghua Gu
  • Fused bicyclic carboxamide derivatives and methods of their use
    Publication number: 20050054630
    Abstract: Fused bicyclic carboxamide derivatives are disclosed. Pharmaceutical compositions containing the compounds and methods for their use are also disclosed.
    Type: Application
    Filed: August 28, 2003
    Publication date: March 10, 2005
    Inventors: Roland Dolle, Guo-Hua Chu