Patents by Inventor Guo Q. Shi

Guo Q. Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fused-aromatic compounds having anti-diabetic activity
    Patent number: 7834036
    Abstract: Fused aromatic compounds of Formula (I) are PPAR gamma agonists or partial agonists and are useful in the treatment or control of type II diabetes, including hyperglycemia, dyslipidermia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: November 16, 2010
    Assignee: Merck Sharp & Dohme Corp
    Inventors: Harold B. Wood, Peter T. Meinke, Guo Q. Shi, Yong Zhang
  • Antidiabetic oxazolidinediones and thiazolidinediones
    Patent number: 7807692
    Abstract: Phenoxyphenyl and phenoxybenzyl oxazolidine-2,4-diones and thiazolidine-2,4-diones are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: October 5, 2010
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: James F. Dropinski, Peter T. Meinke, Guo Q. Shi, Yong Zhang
  • Antidiabetic Oxazolidinediones and Thiazolidinediones
    Publication number: 20100168164
    Abstract: Phenoxyphenyl and phenoxybenzyl oxazolidine-2,4-diones and thiazolidine-2,4-diones are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.
    Type: Application
    Filed: June 30, 2006
    Publication date: July 1, 2010
    Inventors: James F. Dropinski, Peter T. Meinke, Guo Q. Shi, Yong Zhang
  • Compounds for the treatment of dyslipidemia and other lipid disorders
    Patent number: 7629372
    Abstract: A class of compounds having Formula I and pharmaceutically acceptable salts thereof are useful as therapeutic compounds, particularly in the treatment of hyperlipidemia, hypercholesterolemia, dyslipidemia, and other lipid disorders, and in delaying the onset of or reducing the risk of developing conditions and sequelae that are associated with these diseases, such as atherosclerosis.
    Type: Grant
    Filed: September 12, 2005
    Date of Patent: December 8, 2009
    Assignee: Merck & Co., Inc.
    Inventors: James F. Dropinski, Guo Q. Shi, Yong Zhang
  • PPAR alpha selective compounds for the treatment of dyslipidemia and other lipid disorders
    Patent number: 7524882
    Abstract: A class of benzodihydrofuran compounds having the structure of formula (I) below and pharmaceutically acceptable salts thereof are useful as therapeutic compounds, particularly in the treatment of hyperlipidemia, hypercholesterolemia, dyslipidemia, and other lipid disorders, and in delaying the onset of or reducing the risk of conditions and sequelae that are associated with these diseases, such as atherosclerosis.
    Type: Grant
    Filed: July 25, 2003
    Date of Patent: April 28, 2009
    Assignee: Merck & Co., Inc.
    Inventors: Guo Q. Shi, Yong Zhang
  • Antidiabetic Oxazolidinediones and Thiazolidinediones
    Publication number: 20090069385
    Abstract: Pyridinyloxyphenyl and pyridinyloxybenzyl oxazolidine-2,4-diones and thiazolidine-2,4-diones are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.
    Type: Application
    Filed: July 14, 2006
    Publication date: March 12, 2009
    Inventors: Peter T. Meinke, Guo Q. Shi, Harold B. Wood
  • Fused-Aromatic Compounds Having Anti-Diabetic Activity
    Publication number: 20080194586
    Abstract: Fused aromatic compounds of Formula (I) are PPAR gamma agonists or partial agonists and are useful in the treatment or control of type II diabetes, including hyperglycemia, dylipidermia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.
    Type: Application
    Filed: March 3, 2006
    Publication date: August 14, 2008
    Inventors: Harold B. Wood, Peter T. Meinke, Guo Q. Shi, Yong Zhang