Patents by Inventor Guoqiang SONG

Guoqiang SONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11091510
    Abstract: The present invention provides the preparation processes for several crystal forms of the compound 17beta-Neriifolin (17bNF) and use thereof in anti-tumor applications. The present invention provides preparation processes for four kinds of non-solvated crystal forms, amorphous powders and eleven kinds of solvated crystalline solids, including ethanol-solvated ones, of 17bNF that are not present in nature, and the identification and characterization of these crystal forms by crystallographic research methods such as X-ray powder diffraction. In addition, through vivo anti-tumor experiments with five of the crystal forms in nude mice, we provide anti-tumor and anti-cancer applications of the crystal forms of 17bNF.
    Type: Grant
    Filed: November 19, 2019
    Date of Patent: August 17, 2021
    Assignees: ENKANG PHARMACEUTICALS (GUANGZHOU), LTD., ENZHI (GUANGZHOU) PHARMACEUTICALS LIMITED, ENZYNOMICS (H.K.) LIMITED, FOSHAN INTELGEN PHARMACEUTICAL CO. LTD.
    Inventors: Chun Liang, Haibin Liu, Zeming Zhang, Guoqiang Song, Yushan Li, Weiqiang Zhang
  • Publication number: 20200157139
    Abstract: The present invention provides the preparation processes for several crystal forms of the compound 17beta-Neriifolin (17bNF) and use thereof in anti-tumor applications. The present invention provides preparation processes for four kinds of non-solvated crystal forms, amorphous powders and eleven kinds of solvated crystalline solids, including ethanol-solvated ones, of 17bNF that are not present in nature, and the identification and characterization of these crystal forms by crystallographic research methods such as X-ray powder diffraction. In addition, through vivo anti-tumor experiments with five of the crystal forms in nude mice, we provide anti-tumor and anti-cancer applications of the crystal forms of 17bNF.
    Type: Application
    Filed: November 19, 2019
    Publication date: May 21, 2020
    Applicants: ENZHI (GUANGZHOU) PHARMACEUTICALS LIMITED, ENZYNOMICS (H.K.) LIMITED, FOSHAN INTELGEN PHARMACEUTICAL CO. LTD.
    Inventors: Chun LIANG, Haibin LIU, Zeming ZHANG, Guoqiang SONG, Yushan LI, Weiqiang ZHANG