Abstract: A method of improving a field operation that comprises a gas injection may include assessing a plurality of potential injection gases against a plurality of values of a plurality of parameters associated with a plurality of samples, where each of the plurality of potential injection gases comprises an acidic component, and where the plurality of parameters comprises fluid chemistry parameters and rock properties. The method may also include determining a proposed injection gas from among the plurality of potential injection gases for the field operation that comprises the gas injection to be performed using a first wellbore in fluidic communication with a first subterranean formation, a second wellbore in fluidic communication with the first subterranean formation, a third wellbore in fluidic communication with a second subterranean formation, or any combination thereof.

Abstract: A voltage regulator system of an information handling system includes a Smart Power Stage (SPS) and a voltage regulator controller. The SPS includes a high-side transistor and a low-side transistor. The voltage regulator controller detects a normal power down of the information handling system and sets bleed state for the SPS to a first state. Based on the bleed state being set to the first state, the voltage regulator controller provides a first control voltage to the low-side transistor and a second control voltage to the high-side transistor. The first control voltage causes the low-side transistor to be fully turned on, and the second control voltage causes the high-side transistor to be in a linear region. In response to a predetermined amount of time expiring, the voltage regulator controller enters the SPS in an idle mode.

Abstract: A semiconductor structure includes a first transistor, a second transistor, a first dummy source/drain, a third transistor, a fourth transistor, and a second dummy source/drain. The first transistor and a second transistor adjacent to the first transistor are at a first elevation. The first dummy source/drain is disposed at the first elevation. The third transistor and a fourth transistor adjacent to the third transistor, are at a second elevation different from the first elevation. The second dummy source/drain is disposed at the second elevation. The second transistor is vertically aligned with the third transistor. The first dummy source/drain is vertically aligned with a source/drain of the fourth transistor. The second dummy source/drain is vertically aligned with a source/drain of the first transistor. The gate structure between the second dummy source/drain and a source/drain of the third transistor is absent. A method for manufacturing a semiconductor structure is also provided.

Abstract: A method and system for providing access to a resource. A request for an individual within an organization to access the resource is received. In response to the request having been received, at least one constraint for accessing the resource by the individual is ascertained, based on respective constraints for accessing the resource by one or more other individuals in the organization. The one or more other individuals have a same role in the organization as the individual or have a respective relationship with the individual. The at least one constraint is provided to the individual.

Abstract: The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: A light-emitting element includes a pair of electrodes, a first light-emitting unit, a second light-emitting unit, and a charge generation layer. The first light-emitting unit, between the pair of electrodes, and the first light-emitting unit, includes a first light-emitting layer. The second light-emitting unit, between the pair of electrodes, includes a second light-emitting layer. A first luminescent layer includes a first main body material, a second main body material, a first guest material, and a first auxiliary material, and the first main body material forms a first excimer complex with the second main body material. A first excited triplet state energy level of the first auxiliary material is lower than a first excited triplet state energy level of the first excimer complex, and the first excited triplet state energy level of the first auxiliary material is higher than that of the first guest material.

Abstract: A gas extraction device for metal mineral inclusions and a gas extraction method therefor are provided, the device includes a base plate, an annular carrier, sealing covers, a grinding assembly, a vacuum assembly, a gas-gathering assembly and a mass spectrometer. The annular carrier is disposed on the base plate, multiple grinding chambers are defined and evenly distributed in a circular shape on the annular carrier, the sealing covers are disposed at openings of the grinding chambers, the grinding assembly includes grinding hammers, and the grinding hammers penetrate through the sealing covers and extend into the grinding chambers. Side walls of each grinding chamber defines a first through hole and a second through hole. The vacuum assembly is communicated with the grinding chambers through the first through holes. The gas-gathering assembly is communicated with the grinding chambers through the second through holes. The mass spectrometer is communicated with the gas-gathering assembly.

Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Abstract: A laser brazing and welding system is disclosed and includes: a laser; a first cutting tool including a first cutting tip; and a control module. The control module is configured to control the laser to laser braze or laser weld two parts; and control ultrasonic vibration of the first cutting tip to remove one or more layers from at least one of the two parts prior to or subsequent to the laser brazing or laser welding of the two parts.

Abstract: A wheel mechanism includes a fixing base, a wheel base, a wheel, a fixing tube and a gasket. The gasket is disposed around the fixing tube to prevent the wheel with the wheel base from moving up and down. The upper gasket may be disposed between the fixing base and the wheel base to prevent the fixing base and the wheel base from colliding with each other to generate noise. The lower gasket may be disposed between the wheel base and the fixing tube to prevent the wheel base and the fixing tube from colliding with each other to generate noise. Further, when the wheel base is pivotally connected to the fixing base by the rotating shaft, the invention may selectively dispose at least one resilient member between at least two of the fixing base, the wheel base and the rotating shaft to prevent the wheel from shimmying.

Abstract: Disclosed are a method for the synthesis of roxadustat and an intermediate thereof, and an intermediate thereof. In particular, disclosed is a method for the synthesis of compound M1, the method comprising the following steps: carrying out a reaction as shown below between compound SM and compound SM-A under the action of an oxidizing agent. The method of the present invention uses cheap and easily available raw materials, has short reaction steps, produces a high yield, has simple and convenient post-treatment procedures, and is suitable for industrial production.

Abstract: The present invention provides a method for testing and fitting the dihedral angle parameters in force field. The method first generates some representative conformations, and then compares the results of force field and quantum mechanics methods using these structures. If the results meet the predefined standards, the process ends; otherwise the molecule will be cut into small-size molecular fragments with only one flexible dihedral angle in each fragment. The dihedral angles will be scanned. And results of force field and quantum mechanics will be compared for each scanned flexible dihedral angle to find out those that do not meet the standards, and their parameters will be selected for further fitting. After new dihedral angle parameters are obtained, apply them to the original series of conformers of the whole molecule for validation. If results meet the standards, complete the whole process of testing and fitting poorly performing dihedral angle parameters.

Abstract: The present invention is applicable to the fields of panoramic images and videos, and provides a panoramic image and video splicing method, and a panoramic camera. In the present invention, fisheye photos captured by two adjacent cameras are mapped to corresponding seam areas of a sphere model, so as to form two strip graphs having overlapping areas; performing block template matching on the two strip graphs to obtain an initial template matching result; performing matching filtering on the initial template matching result by using an area expansion-based matching filtering algorithm, so as to obtain a final matching result; and updating a mapping relationship between the fisheye photos and the corresponding seam areas of the sphere model, and performing panoramic splicing according to the updated mapping relationship to obtain a seamless panoramic image.

Abstract: Described herein are methods and compositions related to the treatment or prevention of an inflammatory disease via administration of an agent that inhibits a long noncoding RNA (Inc-RNA) expressed in a macrophage to a subject in need thereof. In one embodiment, the Inc-RNA is lnc-FAM164A1. Another aspect herein provides a method of treating or preventing an inflammatory disease via administration of an agent that inhibits a protein bound to a Inc-RNA, e.g., ACLY, to a subject in need thereof.

Abstract: A method for web application layer attack detection and defense based on behavior characteristic matching and analysis includes presetting a defense rule base, the defense rule base including a plurality of defense rules; acquiring a record that access request data matches the defense rule base in a web application protection system and taking the record as sample data; learning the sample data to establish an analysis model; establishing a user reputation database and setting a blacklist module in the user reputation database; learning the user's access behavior through the analysis model and updating and correcting the defense rules in the defense rule base; establishing an exception defense rule base; and setting a defense method and intercepting the user's access behavior according to the defense method. By intelligently learning the user's behavior, threat behavior can be identified and intercepted quickly to ensure the security of the web server.

Abstract: A diagnostic assistance method is provided in the invention. The diagnostic assistance method includes the steps of generating audio data with a stethoscope; generating image data via an ultrasonic device; processing the audio data through a first processing module to generate a first result; processing the image data through a second processing module to generate a second result; and generating a diagnostic assistance result according to the first result and the second result.

Abstract: An ultrasonic-based pulse-taking device and a pulse-taking method thereof which are adapted to detect a pulse condition of a person are provided. The pulse-taking method includes: sensing a blood vessel of the person to generate a color Doppler image and a blood flow waveform image. Determining the pulse condition based on the color Doppler image and the blood flow waveform image.

Abstract: Data input supporting method and apparatus are disclosed. The data input supporting method includes receiving virtual data sent by an intelligent mobile device, analyzing the received virtual data according to a pre-stored key value mapping file, the key value mapping file saving a mapping relationship between the virtual data and a real instruction, encapsulating the real instruction obtained by analyzing the virtual data, and sending the encapsulated real instruction to a pre-established virtual device node, filling the real instruction into a corresponding system function by the virtual device node automatically according to an instruction type; and responding to a kernel space data injection event generated by filling the real instruction into the system function. Embodiments of the invention can support non-contact control of the intelligent mobile device to an electronic product through a wireless connection, thereby providing desirable user experience.

Abstract: A method for web application layer attack detection and defense based on behavior characteristic matching and analysis includes presetting a defense rule base, the defense rule base including a plurality of defense rules; acquiring a record that access request data matches the defense rule base in a web application protection system and taking the record as sample data; learning the sample data to establish an analysis model; establishing a user reputation database and setting a blacklist module in the user reputation database; learning the user's access behavior through the analysis model and updating and correcting the defense rules in the defense rule base; establishing an exception defense rule base; and setting a defense method and intercepting the user's access behavior according to the defense method. By intelligently learning the user's behavior, threat behavior can be identified and intercepted quickly to ensure the security of the web server.

Abstract: Provided are polyethylene glycol drug conjugates of general formula (I), (II) or (III) and pharmaceutical compositions and a use thereof. The conjugates are formed by combining low molecular weight polyethylene glycol with 2-4 drug molecules. The conjugates can interact with receptor dimers or polymers, thereby improving the in vivo distribution of the drug, changing the oil and water distribution coefficient, enhancing the pharmacological activity, reducing the blood-brain barrier permeability of the drug, and improving the bioavailability of the drug.