Patents by Inventor Guodong Liu

Guodong Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090074718
    Abstract: Erythropoietin obtained from eggs laid by transgenic avians having avian N-linked and O-linked glycosylation patterns.
    Type: Application
    Filed: October 10, 2007
    Publication date: March 19, 2009
    Inventors: Robert D. Ivarie, Alex J. Harvey, Julie A. Morris, Guodong Liu, Jeffrey C. Rapp
  • Publication number: 20080292545
    Abstract: Apoferritin nanoparticles with functionalized surfaces have been prepared that include preselected agents within the cavity of the apoferritin molecule and preselected functionalized surface characteristics on the outer surface of the nanoparticle. Such materials provide for utilization and selective modification in a variety of applications including therapeutic and diagnostic uses. Examples of several of these applications are described herein. In addition a method for the creation of these materials by alternatively assembling, functionalizing, or functionalizing, disassembling and reassemblying the materials provides for creative customization of various types of materials applicable for varying types of applications which are also described herein.
    Type: Application
    Filed: April 4, 2008
    Publication date: November 27, 2008
    Inventors: Yuehe Lin, Guodong Liu, Hong Wu, Jun Wang, Darrell R. Fisher
  • Patent number: 7452452
    Abstract: The present invention relates to microelectode arrays (MEAs), and more particularly to carbon nanotube nanoelectrode arrays (CNT-NEAs) for chemical and biological sensing, and methods of use.
    Type: Grant
    Filed: December 20, 2004
    Date of Patent: November 18, 2008
    Assignee: The Trustees of Boston College
    Inventors: Zhifeng Ren, Yuehe Lin, Wassana Yantasee, Guodong Liu, Fang Lu, Yi Tu
  • Patent number: 7445774
    Abstract: This invention provides for human interferon-? which includes novel glycosylation structures.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: November 4, 2008
    Assignees: AviGenics, Inc., University of Georgia Research Foundation, Inc.
    Inventors: Robert D. Ivarie, Alex J. Harvey, Julie A. Morris, Guodong Liu, Jeffrey C. Rapp
  • Publication number: 20080156654
    Abstract: Designs, fabrication and applications of nanostructures made of an alloy of two or more different metal elements to provide a unique identification code based on the composition of the alloy. Such compositionally encoded nanostructures can be in various geometries including but not limited to nanoparticles, nanowires and nanotubes. In one example, a single-step electroplating process may be used to form alloy nanowires without separate electroplating steps.
    Type: Application
    Filed: August 8, 2007
    Publication date: July 3, 2008
    Inventors: Joseph Wang, Guodong Liu
  • Patent number: 7338654
    Abstract: This invention includes compositions comprising glycosylated human interferon-? derived from a chicken.
    Type: Grant
    Filed: March 8, 2006
    Date of Patent: March 4, 2008
    Assignees: AviGenics, Inc., University of Georgia Research Foundation, Inc.
    Inventors: Robert D. Ivarie, Alex J. Harvey, Julie A. Morris, Guodong Liu, Jeffrey C. Rapp
  • Publication number: 20070243165
    Abstract: Granulocyte colony stimulating factor obtained from eggs laid by transgenic avians having newly described G-CSF glycosylation patterns.
    Type: Application
    Filed: February 20, 2007
    Publication date: October 18, 2007
    Inventors: Robert Ivarie, Alex Harvey, Julie Morris, Guodong Liu, Jeffrey Rapp
  • Patent number: 7129390
    Abstract: This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of avians in order to express the exogenous sequences to alter the phenotype of the avians or to produce desired proteins. In particular, transgenic avians are produced which express exogenous sequences in their oviducts and which deposit exogenous proteins into their eggs. Avian eggs that contain exogenous proteins are encompassed by this invention. The instant invention further provides novel forms of interferon and erythropoietin which are efficiently expressed in the oviduct of transgenic avians and deposited into avian eggs.
    Type: Grant
    Filed: January 24, 2003
    Date of Patent: October 31, 2006
    Assignees: AviGenics, Inc, University of Georgia Research Foundation, Inc.
    Inventors: Robert D. Ivarie, Alex J. Harvey, Julie A. Morris, Guodong Liu, Jeffrey C. Rapp
  • Publication number: 20060188478
    Abstract: This invention provides for human interferon-? which includes novel glycosylation structures.
    Type: Application
    Filed: February 28, 2006
    Publication date: August 24, 2006
    Inventors: Robert Ivarie, Alex Harvey, Julie Morris, Guodong Liu, Jeffrey Rapp
  • Publication number: 20060185024
    Abstract: This invention provides for proteins which are expressed in the avian oviduct, packaged into eggs laid by the avian, then isolated.
    Type: Application
    Filed: March 15, 2006
    Publication date: August 17, 2006
    Inventors: Robert Ivarie, Alex Harvey, Julie Morris, Guodong Liu, Jeffrey Rapp
  • Publication number: 20060185029
    Abstract: This invention provides for proteins which are expressed in the avian oviduct, packaged into eggs laid by the avian.
    Type: Application
    Filed: January 23, 2006
    Publication date: August 17, 2006
    Inventors: Robert Ivarie, Alex Harvey, Julie Morris, Guodong Liu, Jeffrey Rapp
  • Publication number: 20060171921
    Abstract: This invention includes compositions comprising glycosylated human interferon-? derived from a chicken.
    Type: Application
    Filed: March 8, 2006
    Publication date: August 3, 2006
    Inventors: Robert Ivarie, Alex Harvey, Julie Morris, Guodong Liu, Jeffrey Rapp
  • Publication number: 20060123488
    Abstract: This invention provides for proteins which are expressed in the avian oviduct, packaged into eggs laid by the avian and removed from the eggs.
    Type: Application
    Filed: January 23, 2006
    Publication date: June 8, 2006
    Inventors: Robert Ivarie, Alex Harvey, Julie Morris, Guodong Liu, Jeffrey Rapp
  • Publication number: 20060075513
    Abstract: This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of a bird and for expressing said exogenous sequences to alter the phenotype of the bird or to produce desired proteins. In particular, transgenic chickens are produced which express exogenous sequences in their oviducts. Eggs which contain exogenous proteins are also produced.
    Type: Application
    Filed: November 15, 2005
    Publication date: April 6, 2006
    Inventors: Robert Ivarie, Alex Harvey, Julie Morris, Guodong Liu, Jeffrey Rapp
  • Publication number: 20060015960
    Abstract: The invention includes avian hard shell eggs containing one or more pharmaceutical proteins wherein the pharmaceutical proteins are exogenous to the egg.
    Type: Application
    Filed: June 24, 2005
    Publication date: January 19, 2006
    Inventors: Robert Ivarie, Alex Harvey, Julie Morris, Guodong Liu, Jeffrey Rapp
  • Publication number: 20050230270
    Abstract: The present invention relates to microelectode arrays (MEAs), and more particularly to carbon nanotube nanoelectrode arrays (CNT-NEAs) for chemical and biological sensing, and methods of use.
    Type: Application
    Filed: December 20, 2004
    Publication date: October 20, 2005
    Inventors: Zhifeng Ren, Yuehe Lin, Wassana Yantasee, Guodong Liu, Fang Lu
  • Publication number: 20050188431
    Abstract: This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of avians in order to express the exogenous sequences to alter the phenotype of the avians or to produce desired proteins. In particular, transgenic avians are produced which express exogenous sequences in their oviducts and which deposit exogenous proteins into their eggs. Avian eggs that contain exogenous proteins are encompassed by this invention. The instant invention further provides novel forms of interferon and erythropoietin which are efficiently expressed in the oviduct of transgenic avians and deposited into avian eggs.
    Type: Application
    Filed: April 6, 2005
    Publication date: August 25, 2005
    Inventors: Robert Ivarie, Alex Harvey, Julie Morris, Guodong Liu, Jeffrey Rapp
  • Publication number: 20050188430
    Abstract: This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of avians in order to express the exogenous sequences to alter the phenotype of the avians or to produce desired proteins. In particular, transgenic avians are produced which express exogenous sequences in their oviducts and which deposit exogenous proteins into their eggs. Avian eggs that contain exogenous proteins are encompassed by this invention. The instant invention further provides novel forms of interferon and erythropoietin which are efficiently expressed in the oviduct of transgenic avians and deposited into avian eggs.
    Type: Application
    Filed: April 6, 2005
    Publication date: August 25, 2005
    Inventors: Robert Ivarie, Alex Harvey, Julie Morris, Guodong Liu, Jeffrey Rapp
  • Publication number: 20040158882
    Abstract: This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of a bird and for expressing said exogenous sequences to alter the phenotype of the bird or to produce desired proteins. In particular, transgenic chickens are produced which express exogenous sequences in their oviducts. Eggs which contain exogenous proteins are also produced.
    Type: Application
    Filed: October 28, 2003
    Publication date: August 12, 2004
    Applicants: AviGenics, Inc., The University of Georgia Research Foundation, Inc
    Inventors: Robert D. Ivarie, Alex J. Harvey, Julie A. Morris, Guodong Liu
  • Patent number: 6730822
    Abstract: This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of a bird and for expressing said exogenous sequences to alter the phenotype of the bird or to produce desired proteins. In particular, transgenic chickens are produced which express exogenous sequences in their oviducts. Eggs which contain exogenous proteins are also produced.
    Type: Grant
    Filed: October 16, 1998
    Date of Patent: May 4, 2004
    Assignee: AviGenics, Inc.
    Inventors: Robert D. Ivarie, Alex J. Harvey, Julie A. Morris, Guodong Liu, Jeffrey C. Rapp