Patents by Inventor Guodong Shen

Guodong Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11919962
    Abstract: Provided herein are antibodies that bind to the alpha subunit of an IL-7 receptor (IL-7R?). Also provided are uses of these antibodies in therapeutic applications, such as treatment of inflammatory diseases. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain regions of the antibodies, and vectors comprising the polynucleotides.
    Type: Grant
    Filed: April 16, 2021
    Date of Patent: March 5, 2024
    Assignee: Bristol Myers-Squibb Company
    Inventors: Aaron Paul Yamniuk, Scott Ronald Brodeur, Ekaterina Deyanova, Richard Yu-Cheng Huang, Yun Wang, Alfred Robert Langish, Guodong Chen, Stephen Michael Carl, Hong Shen, Achal Mukundrao Pashine, Lin Hui Su
  • Publication number: 20240002604
    Abstract: A silicone resin is suitable as an intermediate for producing a solid silicone-modified polyester, a process for preparing the solid silicone-modified polyester using the silicone resin has no gelation issue, and the solid silicone-modified polyester made from the process is suitable for coating compositions with desired properties including good adhesion, impact resistance and heat resistance.
    Type: Application
    Filed: December 8, 2020
    Publication date: January 4, 2024
    Inventors: Wenjie CHEN, Guodong SHEN, Zhihua LIU, Jiayin ZHU
  • Patent number: 11472983
    Abstract: A composition which provides a coating film having excellent foul releasing property is disclosed. The composition comprises, based on the solid contents of the composition: (A) 20 to 80 weight % of a resin which has a polydialkylsiloxane unit and an epoxy resin unit within its structure; (B) 0.1 to 5 weight % of an amino silane; (C) 0.5 to 5 weight % of a hydrophilic additive; and (D) 0.1 to 5 weight % of a catalyst. A coating, e.g. a coating film, formed from the composition generally has an amphiphilic surface. Thus, the composition is suitable for coatings which prevent both hydrophobic and hydrophilic fouling.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: October 18, 2022
    Assignees: DOW GLOBAL TECHNOLOGIES LLC, DOW SILICONES CORPORATION
    Inventors: Linfei Wang, Xiaomei Song, Hongyu Chen, Guodong Shen, Yunlong Guo
  • Patent number: 11326059
    Abstract: A coating composition is disclosed. The coating composition is useful for providing a coating, e.g. on a surface of an article. The coating provides very low adhesion to ice, faster ice removal by heating power, etc. The coating composition comprises a silicone rubber, a thermal conductive filler, a reactive polysiloxane, an unsaturated group containing alkoxysilane, a catalyst, and a solvent.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: May 10, 2022
    Assignees: DOW GLOBAL TECHNOLOGIES LLC, DOW SILICONES CORPORATION
    Inventors: Xiaomei Song, Yu Chen, Hongyu Chen, Guodong Shen, Wenjie Chen, Jo Gunn, Chungmien Kuo
  • Patent number: 11299594
    Abstract: Provided herein is a carbinol-functional silicone resin. The carbinol-functional silicone resin is prepared by reacting a raw silicone resin having at least 1 mass % of silicon atom-bonded hydroxyl groups, silicon atom-bonded alkoxy groups, or a combination thereof, and a dihydroxy-functional compound, in the presence of a condensation catalyst and a solvent. The carbinol-functional silicone resin can produce a solid silicone-modified polyester without gelation of the silicone resin.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: April 12, 2022
    Assignee: DOW SILICONES CORPORATION
    Inventors: Guodong Shen, Wenjie Chen, Zhihua Liu
  • Publication number: 20210155759
    Abstract: Provided herein is a carbinol-functional silicone resin. The carbinol-functional silicone resin is prepared by reacting a raw silicone resin having at least 1 mass% of silicon atom-bonded hydroxyl groups, silicon atom-bonded alkoxy groups, or a combination thereof, and a dihydroxy-functional compound, in the presence of a condensation catalyst and a solvent. The carbinol-functional silicone resin can produce a solid silicone-modified polyester without gelation of the silicone resin.
    Type: Application
    Filed: April 18, 2018
    Publication date: May 27, 2021
    Inventors: Guodong SHEN, Wenjie CHEN, Zhihua LIU
  • Publication number: 20210115295
    Abstract: A coating composition is disclosed. The coating composition generally provides a coating which is easy to clean, e.g. from an oil stain. The coating composition contains, based on the solid contents of the coating composition; (A) 72 to 90 weight % of a methylpolysiloxane resin; (B) 3 to 8 weight % of a polydimethylsiloxane; (C) 7 to 18 weight % of a silane adhesion promoter with a specific chemical structure; and (D) 0.1 to 0.3 weight % of a catalyst. The coating composition optionally contains (E) a reaction product of a composition containing diisocyanate and polydimethylsiloxane. The coating composition optionally contains (F) a fluorinated silane, in addition or alternate to component (E).
    Type: Application
    Filed: January 31, 2018
    Publication date: April 22, 2021
    Applicants: DOW GLOBAL TECHNOLOGIES LLC, DOW SILICONES CORPORATION
    Inventors: Xiaomei SONG, Guodong SHEN, Hongyu CHEN, Linfei WANG, Yunlong GUO
  • Publication number: 20210054204
    Abstract: A composition which provides a coating film having excellent foul releasing property is disclosed. The composition comprises, based on the solid contents of the composition: (A) 20 to 80 weight % of a resin which has a polydialkylsiloxane unit and an epoxy resin unit within its structure; (B) 0.1 to 5 weight % of an amino silane; (C) 0.5 to 5 weight % of a hydrophilic additive; and (D) 0.1 to 5 weight % of a catalyst. A coating, e.g. a coating film, formed from the composition generally has an amphiphilic surface. Thus, the composition is suitable for coatings which prevent both hydrophobic and hydrophilic fouling.
    Type: Application
    Filed: April 27, 2018
    Publication date: February 25, 2021
    Inventors: Linfei WANG, Xiaomei SONG, Hongyu CHEN, Guodong SHEN, Yunlong GUO
  • Publication number: 20210010893
    Abstract: The disclosure provides a pipeline leak detection device and a leak detection method based on the variational mode decomposition optimized by the particle swarm (PSO-VMD). The acoustic emission signals with leakage and without leakage are collected by the acoustic emission system. Since the decomposition result of the traditional VMD depends on the selection of the parameter preset scale K and the penalty coefficient ?, the PSO is employed to obtain the optimal parameters of the VMD. The optimized parameters are input into VMD to decompose the original signals, and then K intrinsic mode functions (IMFs) can be obtained. After the signal reconstruction for de-noising, based on the energy ratio, the time-domain features are extracted and the support vector machine (SVM) is used to detect the leak.
    Type: Application
    Filed: September 29, 2020
    Publication date: January 14, 2021
    Inventors: Juncheng JIANG, Xu DIAO, Lei NI, Haitao BIAN, Zhaozhao CHI, Chengwei CHU, Zhirong WANG, Guodong SHEN
  • Publication number: 20200385609
    Abstract: A coating composition which provides a coating with a very low adhesion to ice is disclosed. The coating composition contains a cross-linked silicone binder resin and an elastomeric silicone powder.
    Type: Application
    Filed: July 31, 2017
    Publication date: December 10, 2020
    Inventors: Yu CHEN, Xiaomei SONG, Guodong SHEN, Wenjie CHEN, Hongyu CHEN
  • Publication number: 20200231821
    Abstract: A coating composition is disclosed. The coating composition is useful for providing a coating, e.g. on a surface of an article. The coating provides very low adhesion to ice, faster ice removal by heating power, etc. The coating composition comprises a silicone rubber, a thermal conductive filler, a reactive polysiloxane, an unsaturated group containing alkoxysilane, a catalyst, and a solvent.
    Type: Application
    Filed: September 7, 2017
    Publication date: July 23, 2020
    Inventors: Xiaomei SONG, Yu CHEN, Hongyu CHEN, Guodong SHEN, Wenjie CHEN, Jo GUNN, Chungmien KUO
  • Publication number: 20200157380
    Abstract: A coating composition which provides a coating with a very low adhesion to ice is disclosed. The coating composition contains methylpolysiloxane resin and a lubricant package comprising two kinds of different siloxane fluids.
    Type: Application
    Filed: July 31, 2017
    Publication date: May 21, 2020
    Inventors: Yu CHEN, Xiaomei SONG, Guodong SHEN, Hongyu CHEN
  • Patent number: 9398441
    Abstract: Embodiments of the present invention provide a method for identifying a re-subscribed user and a corresponding apparatus. Based on call records of a user, communication numbers of the user which meet a preset condition are identified. Then a re-subscribed user is identified by calculating a communication number coincidence rate between users within different charging periods. In accordance with the present invention, call records of users are used as a basis of comparative analysis, thereby improving an accuracy rate of identifying a re-subscribed user; a new method is practiced to sequenced communication numbers of a user and group communication records, thereby effectively reducing the number of calculations and improving calculation efficiency.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: July 19, 2016
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Shikai Liu, Guodong Shen
  • Publication number: 20150264556
    Abstract: Embodiments of the present invention provide a method for identifying a re-subscribed user and a corresponding apparatus. Based on call records of a user, communication numbers of the user which meet a preset condition are identified. Then a re-subscribed user is identified by calculating a communication number coincidence rate between users within different charging periods. In accordance with the present invention, call records of users are used as a basis of comparative analysis, thereby improving an accuracy rate of identifying a re-subscribed user; a new method is practiced to sequenced communication numbers of a user and group communication records, thereby effectively reducing the number of calculations and improving calculation efficiency.
    Type: Application
    Filed: June 2, 2015
    Publication date: September 17, 2015
    Inventors: Shikai Liu, Guodong Shen