Patents by Inventor Guofeng Wu
Guofeng Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11955663Abstract: This application provides a battery module and an assembling method thereof. The battery module includes batteries and busbar components. The batteries are arranged consecutively along a longitudinal direction of the battery module. Each battery includes a first electrode terminal and a second electrode terminal. The busbar components are connected to the batteries. The batteries include a first battery and a second battery. The first electrode terminal of the first battery and the first electrode terminal of the second battery are arranged along the longitudinal direction. The busbar components include a first busbar component, and the first busbar component includes a first part, a second part, and a third part.Type: GrantFiled: December 18, 2020Date of Patent: April 9, 2024Assignee: CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITEDInventors: Changjin Wen, Ye Xu, Anwei Wu, Guofeng Liu, Xiaorong Liu, Bin Zhao
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Publication number: 20240092726Abstract: The present disclosure discloses a method for synthesizing quinolones intermediates by a continuous flow reaction. Specifically, according to the method, a microchannel reactor is used, which improves the selectivity and conversion rate of the reaction, and the conversion rate of compound ii is increased to more than 95% and the yield is increased to more than 85%; avoids the use of a solvent such as methanol, and methyl tert-butyl ether, etc., in the intermittent reaction process, which simplifies the post-processing method, shortens the overall operation time from about 24 hours to a few minutes, greatly improving the production efficiency, and realizing the continuity and automation of the whole process; and thus makes the product have high purity and high yield, which is suitable for industrial production.Type: ApplicationFiled: March 20, 2023Publication date: March 21, 2024Inventors: Li SHENG, Yuquan LUO, Gang FAN, Long CHEN, Junwei CHEN, Chunlei LV, Guofeng WU, Dadong SHEN, Lin ZHAO, Yunxia GONG
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Publication number: 20230233577Abstract: A 17?-estradiol/vitamin C molecular complex is obtained by compounding of 17?-estradiol and vitamin C in a molar ratio of 0.25:1, 0.5:1, 0.75:1, 1:1, 1:0.25, 1:0.5, or 1:0.75. A preparation method and use of the 17?-estradiol/vitamin C molecular complex are further provided. The 17?-estradiol/vitamin C molecular complex can be distributed to a bone tissue in a bone-targeted manner, which not only significantly improves the anti-osteoporosis activity of 17?-estradiol but also effectively prevents the side effects of endometrial hyperplasia and thrombosis caused by treatment with 17?-estradiol and conjugated estrogens.Type: ApplicationFiled: September 10, 2020Publication date: July 27, 2023Applicant: ZHEJIANG MEDICINE CO., LTD.XINCHANG PHARMACEUTICAL FACTORYInventors: Shiqi PENG, Guofeng WU, Ming ZHAO
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Publication number: 20230201189Abstract: Provided in the present disclosure are a nemonoxacin malate active pharmaceutical ingredient with low combination impurities, and a preparation method thereof, specifically, provided in the present disclosure is a method for preparing the nemonoxacin malate active pharmaceutical ingredient, the method includes the following steps: 1) providing a C1-C3 alcohol/water mixed solvent in which nemonoxacin free base (Formula II) and D,L-malic acid are dissolved; and 2) performing cooling crystallization on a mixed solution obtained in the step 1), and then performing solid-liquid separation, washing and drying on a precipitated solid, so as to obtain the nemonoxacin malate active pharmaceutical ingredient.Type: ApplicationFiled: December 12, 2022Publication date: June 29, 2023Inventors: Li SHENG, Gang FAN, Dadong SHEN, Guofeng WU, Xufeng WU, Haoling GAO, Lanfang ZHU
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Publication number: 20230183259Abstract: The present invention provides a crystal form of a thiofuran pyridazine compound, a preparation method therefor and an application thereof. The crystal form of the thiofuran pyridazine compound is (S)-2-(4-fluorophenyl)-4-(piperidine-3-aminomethyl)thieno[2,3-d] pyridazine-7-carboxamide hydrochloride of formula (I). The crystal form of the thiofuran pyridazine compound in the present invention has higher stability and is stored especially in high humidity conditions, and thus is suitable for preparing various forms of drugs.Type: ApplicationFiled: April 17, 2020Publication date: June 15, 2023Inventors: Dadong SHEN, Yonghui LV, Guofeng WU, Dingfeng ZHANG, Ruiwei CAO
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Patent number: 11633714Abstract: A preparation method for a combined modified straw active particulate carbon adsorption material and use of same. The preparation method for the combined modified straw active particulate carbon adsorption material comprises the following steps: 1) mixing straw powders, distilled water, a binder and a composite mineral, then pelletizing same, and then placing same in a tube furnace for pyrolysis to prepare straw particulate carbon; 2) introducing an inert gas into a modification reagent, adjusting the pH value combined and 3) soaking the straw particulate carbon into the combined modification solution for 30 min, and performing cleaning and drying, so as to obtain a combined modified straw active particulate carbon adsorption material. The combined modified straw active particulate carbon has a good adsorption effect on phosphate group in low-pollution water.Type: GrantFiled: November 26, 2018Date of Patent: April 25, 2023Assignee: JIANGSU ACADEMY OF AGRICULTURAL SCIENCESInventors: Enhui Sun, Hongying Huang, Hongmei Jin, Guofeng Wu, Zhizhou Chang, Xiaomei Ye, Yueding Xu, Cheng Yong
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Publication number: 20230002604Abstract: The present invention discloses a polypropylene composition. A resin matrix is composed of copolymerized polypropylene and branched polyethylene with special parameters, such that the resin matrix has a low crystallization tendency, thereby improving spraying adhesion of a surface of the resin matrix. A polyolefin elastomer (POE) in bimodal distribution is further used to improve the appearance after molding.Type: ApplicationFiled: August 23, 2022Publication date: January 5, 2023Inventors: Jiajie CHEN, Xianbo HUANG, Nanbiao YE, Guofeng WU, Zhongfu LUO, Bo YANG, Zhengya DING
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Publication number: 20220335868Abstract: A display position adjustment method and device, a terminal device, and a non-transitory computer-readable storage medium are disclosed. The method may include: obtaining a current display position of a target component (S101); determining an adjustment scheme for the target component according to a preset display position, where the preset display position includes a position of the display position of the target component relative to a horizontal plane (S102); and adjusting the display position of the target component according to the adjustment scheme (S103).Type: ApplicationFiled: June 28, 2020Publication date: October 20, 2022Inventor: Guofeng WU
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Publication number: 20220101977Abstract: Disclosed is an intelligent intracranial hematoma removal and drainage system, including: an information input module, an information detection module, an intelligent module and a hematoma removal and drainage module, wherein the information input module is used for collecting preoperative data and transmitting the collected preoperative data to the intelligent module; the information detection module is used for acquiring intracranial data monitored in real time and transmitting the monitored intracranial data to the intelligent module; the intelligent module is used for receiving the data from the information input module and the information detection module, analyzing the received data to make a determination, and converting the determination into an instruction signal and transmitting the same to the hematoma removal and drainage module; and the hematoma removal and drainage module is used for receiving an instruction from the intelligent module to remove and drain intracranial hematomas, and feeding dataType: ApplicationFiled: October 11, 2019Publication date: March 31, 2022Inventors: Wenjie Liu, Shaofei Cui, Zhouping Tang, Shirun Yang, Yuanwei Li, Guofeng Wu, Qingwu Yang, Zhizeng Zhao, Yu Li
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Publication number: 20210163709Abstract: Disclosed is a low-odor combustion-delaying polyolefin composition, which includes the following components by weight percentage: 56% to 99.7% of polyolefin; 0.3% to 2% of an ethoxyamide polymer; 0% to 2% of a delay combustion synergist; and 0% to 40% of a filler. Disclosed is also a use of the ethoxyamide polymer as a delay combustion agent in the polyolefin composition.Type: ApplicationFiled: August 6, 2019Publication date: June 3, 2021Applicant: KINGFA SCI. & TECH. CO., LTD.Inventors: Fei YU, Xianbo HUANG, Zhongfu LUO, Nanbiao Ye, Zhengya DING, Bo YANG, Guofeng WU, Jiajie CHEN
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Publication number: 20200298202Abstract: A preparation method for a combined modified straw active particulate carbon adsorption material and use of same. The preparation method for the combined modified straw active particulate carbon adsorption material comprises the following steps: 1) mixing straw powders, distilled water, a binder and a composite mineral, then pelletizing same, and then placing same in a tube furnace for pyrolysis to prepare straw particulate carbon; 2) introducing an inert gas into a modification reagent, adjusting the pH value combined and 3) soaking the straw particulate carbon into the combined modification solution for 30 min, and performing cleaning and drying, so as to obtain a combined modified straw active particulate carbon adsorption material. The combined modified straw active particulate carbon has a good adsorption effect on phosphate group in low-pollution water.Type: ApplicationFiled: November 26, 2018Publication date: September 24, 2020Inventors: Enhui SUN, Hongying HUANG, Hongmei JIN, Guofeng WU, Zhizhou CHANG, Xiaomei YE, Yueding XU, Cheng YONG
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Patent number: 9745309Abstract: The present invention provides a method for preparing an intermediate compound of sitagliptin represented by formula I. The preparation method comprises: dissolving a compound represented by formula II into an organic solvent; and under the catalysis of fatty acid and effect of chlorosilane, performing a reduction reaction of carbon-carbon double bonds, so as to obtain the intermediate compound of sitagliptin represented by formula I, R being methyl or formoxyl. The preparation method of the present invention avoids precious metal as a catalyst, and accordingly, the cost is low, the post-treatment is simple, the product has a high yield, chemical purity and optical purity, and de % is greater than 99.6%, and the preparation method can be used in synthesis of sitagliptin and is suitable for industrial production.Type: GrantFiled: September 9, 2014Date of Patent: August 29, 2017Assignees: Shanghai Institute of Pharmaceutical Industry, Zhejiang Medicine Co., Ltd.Inventors: Kuaile Lin, Zhengyan Cai, Jing Pan, Weicheng Zhou, Guofeng Wu, Lirong Yue, Dadong Shen
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Patent number: 9718823Abstract: The present invention provides a 2, 6-di-nitrogen-containing substituted purine derivative having a formula (I) structure, or pharmaceutical salt or hydrate thereof, and preparation method and use thereof. The compound is broad spectrum anticancer, low toxicity, high anticancer activity and good stability.Type: GrantFiled: August 27, 2014Date of Patent: August 1, 2017Assignee: ZHEJIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORYInventors: Guofeng Wu, Yongmei Xu, Wei Mao, Chunlin Chen, Zhanggui Wu, Xiaoqin Lin, Jun Wang, Jinna Cai, Sen Xiao, Lili Lv
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Publication number: 20160229859Abstract: The present invention provides a method for preparing an intermediate compound of sitagliptin represented by formula I. The preparation method comprises: dissolving a compound represented by formula II into an organic solvent; and under the catalysis of fatty acid and effect of chlorosilane, performing a reduction reaction of carbon-carbon double bonds, so as to obtain the intermediate compound of sitagliptin represented by formula I, R being methyl or formoxyl. The preparation method of the present invention avoids precious metal as a catalyst, and accordingly, the cost is low, the post-treatment is simple, the product has a high yield, chemical purity and optical purity, and de % is greater than 99.6%, and the preparation method can be used in synthesis of sitagliptin and is suitable for industrial production.Type: ApplicationFiled: September 9, 2014Publication date: August 11, 2016Inventors: Kuaile Lin, Zhengyan Cai, Jing Pan, Weicheng Zhou, Guofeng Wu, Lirong Yue, Dadong Shen
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Publication number: 20160207924Abstract: The present invention provides a 2, 6-di-nitrogen-containing substituted purine derivative having a formula (I) structure, or pharmaceutical salt or hydrate thereof, and preparation method and use thereof. The compound is broad spectrum anticancer, low toxicity, high anticancer activity and good stability.Type: ApplicationFiled: August 27, 2014Publication date: July 21, 2016Applicant: Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical FactoryInventors: Guofeng Wu, Yongmei Xu, Wei Mao, Chunlin Chen, Zhanggui Wu, Xiaoqin Lin, Jun Wang, Jinna Cai, Sen Xiao, Lili Lv
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Publication number: 20150143272Abstract: A method for performing batch management on desktop icons and a digital mobile device are provided. The method is applied to the digital mobile device, including: when confirming that a user selects a desktop edition function, setting each icon on a current display interface to be in a check state; after confirming that the user selects at least one of icons, performing batch management on the selected icons according to user instructions. The device includes: an icon information unit configured to set each icon on a current display interface to be in a check state when confirming that the user selects the desktop edition function; and notify an icon operation unit after confirming that the user selects at least one of icons; the icon operation unit is configured to perform batch management on the selected icons according to user instructions after receiving the notification sent by the icon information unit.Type: ApplicationFiled: June 25, 2012Publication date: May 21, 2015Applicant: ZTE CorporationInventor: Guofeng Wu
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Patent number: 8962827Abstract: Provided are a linezolid intermediate and the preparation method thereof and a method for synthesizing linezolid. The structure of the intermediate is shown as formula F2, wherein the compound is prepared by a condensation reaction of (S)āN-(3-chloro-2-hydroxy-1-propyl) acetamide and the compound shown in formula F4. In the preparation methods of the compound shown in formula F2 and linezolid, the reaction system is mild, side reactions are few and the product yield is high.Type: GrantFiled: April 12, 2012Date of Patent: February 24, 2015Assignee: Zhejiang Medicine Co. Ltd. Xinchang Pharmaceutical FactoryInventors: Xiaoyue Jiang, Guofeng Wu, Weidong Ye, Runpu Shen, Xiaohua Song
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Publication number: 20140024827Abstract: Provided are a linezolid intermediate and the preparation method thereof and a method for synthesizing linezolid. The structure of the intermediate is shown as formula F2, wherein the compound is prepared by a condensation reaction of (S)āNā(3-chloro-2-hydroxy-1-propyl) acetamide and the compound shown in formula F4. In the preparation methods of the compound shown in formula F2 and linezolid, the reaction system is mild, side reactions are few and the product yield is high.Type: ApplicationFiled: April 12, 2012Publication date: January 23, 2014Applicant: ZHEJIANG MEDICINE CO., LTD XINCHANG PHARMACEUTICAL FACTORYInventors: Xiaoyue Jiang, Guofeng Wu, Weidong Ye, Runpu Shen, Xiaohua Song