Patents by Inventor Guofu Li

Guofu Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120004114
    Abstract: Isolated polynucleotides and polypeptides and recombinant DNA constructs useful for improving agronomic traits, compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotide encodes a GSH1 polypeptide.
    Type: Application
    Filed: December 21, 2009
    Publication date: January 5, 2012
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY AND PIONEER HI-BRED INTERNATIONAL
    Inventors: Stephen M. Allen, Jeffrey E. Habben, Guofu Li, Emil M. Orozco, JR., Hajime Sakai, Nicholas J. Bate, Carl R. Simmons, Ken'Ichi Ogawa
  • Patent number: 7947873
    Abstract: Disclosed herein are zinc finger proteins that bind to target sites in a plant gamma-tocopherol methyl transferase (GMT) gene; compositions comprising these GMT-targeted zinc finger proteins and methods of making and using such zinc finger proteins. Also disclosed are methods for modulating the alpha-tocopherol content in various plant organs, particularly seeds, in transgenic plants.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: May 24, 2011
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Guofu Li, Qiang Liu, Andrew Jamieson, Edward Rebar, Mylavarapu Venkatramesh
  • Patent number: 7939327
    Abstract: Disclosed herein are compositions and methods that regulate expression of two or more endogenous genes.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: May 10, 2011
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Jeffrey Miller, Guofu Li, Carl Pabo, Trevor Collingwood
  • Publication number: 20110078826
    Abstract: Compositions and methods for modulating plant development and for increasing yield in a plant are provided. The compositions include a Zm-EREF-Ts sequence. Compositions of the invention comprise amino acid sequences and nucleotide sequences selected from SEQ ID NOS: 1 and 2 as well as variants and fragments thereof. Nucleotide sequences encoding the Zm-EREF-Ts molecule are provided in DNA constructs for expression in a plant of interest are provided for modulating the level of a Zm-EREF-Ts sequence in a plant or a plant part are provided. The methods comprise introducing into a plant or plant part a heterologous polynucleotide comprising a Zm-EREF-Ts sequence of the invention. The level of the Zm-EREF-Ts polypeptide can be increased or decreased. Such method can be used to increase the yield in plants; in one embodiment, the method is used to increase grain yield in cereals.
    Type: Application
    Filed: September 28, 2010
    Publication date: March 31, 2011
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Guofu Li, Jijun Zou
  • Publication number: 20110047650
    Abstract: Compositions and methods for modulating plant development and for increasing yield in a plant are provided. The compositions include a ZMPKL1 sequence. Compositions of the invention comprise amino acid sequences and nucleotide sequences selected from SEQ ID NOS: 2 and 43 as well as variants and fragments thereof. Nucleotide sequences encoding the ZMPKL1 molecule are provided in DNA constructs for expression in a plant of interest are provided for modulating the level of a ZMPKL1 sequence in a plant or a plant part are provided. The methods comprise introducing into a plant or plant part a heterologous polynucleotide comprising a ZMPKL1 sequence of the invention. The level of the ZMPKL1 polypeptide can be increased or decreased. Such method can be used to increase the yield in plants; in one embodiment, the method is used to increase grain yield in cereals.
    Type: Application
    Filed: August 19, 2010
    Publication date: February 24, 2011
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventor: Guofu Li
  • Publication number: 20100269228
    Abstract: Compositions and methods for modulating plant development and for increasing yield in a plant are provided. The compositions include a PC4 sequence. Compositions of the invention comprise amino acid sequences and nucleotide sequences selected from SEQ ID NOS: 1 and 2 as well as variants and fragments thereof. Nucleotide sequences encoding the PC4 molecule are provided in DNA constructs for expression in a plant of interest are provided for modulating the level of a PC4 sequence in a plant or a plant part are provided. The methods comprise introducing into a plant or plant part a heterologous polynucleotide comprising a PC4 sequence of the invention. The level of the PC4 polypeptide can be increased or decreased. Such method can be used to increase the yield in plants; in one embodiment, the method is used to increase grain yield in cereals.
    Type: Application
    Filed: April 1, 2010
    Publication date: October 21, 2010
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventor: Guofu Li
  • Publication number: 20100169998
    Abstract: The invention provides a rapid and efficient method and assay for monitoring yield enhancement in a plant using a measure of silk number. The plant is transformed with a prospective gene associated with yield enhancement. The transformed plant is grown along with non-transformed control plants until silk growth is apparent. The change in the number of silks in the transformed plant correlated to the change in yield for the plant. Therefore, changes in yield enhancement can be estimated in the transformed plant prior to harvest of mature plant tissues.
    Type: Application
    Filed: December 28, 2009
    Publication date: July 1, 2010
    Applicant: PIONEER HI-BRED INTERNATIONAL INC.
    Inventors: Guofu Li, Junli Ji
  • Patent number: 7705139
    Abstract: Disclosed herein are modified plant zinc finger proteins; compositions comprising modified plant zinc finger proteins and methods of making and using modified plant zinc finger proteins. The modified plant zinc finger proteins, in contrast to naturally-occurring plant zinc finger proteins, have a binding specificity that is determined by tandem arrays of modular zinc finger binding unit.
    Type: Grant
    Filed: October 19, 2006
    Date of Patent: April 27, 2010
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Andrew Jamieson, Guofu Li
  • Publication number: 20080233641
    Abstract: Disclosed herein are compositions and methods that regulate expression of two or more endogenous genes.
    Type: Application
    Filed: February 28, 2008
    Publication date: September 25, 2008
    Inventors: Jeffrey Miller, Guofu Li, Carl Pabo, Trevor Collingwood
  • Patent number: 7361635
    Abstract: Disclosed herein are compositions and methods that regulate expression of two or more endogenous genes.
    Type: Grant
    Filed: August 29, 2003
    Date of Patent: April 22, 2008
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Jeffrey Miller, Guofu Li, Carl Pabo, Trevor Collingwood
  • Patent number: 7273923
    Abstract: Disclosed herein are modified plant zinc finger proteins; compositions comprising modified plant zinc finger proteins and methods of making and using modified plant zinc finger proteins. The modified plant zinc finger proteins, in contrast to naturally-occurring plant zinc finger proteins, have a binding specificity that is determined by tandem arrays of modular zinc finger binding units.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: September 25, 2007
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Andrew Jamieson, Guofu Li
  • Patent number: 7262054
    Abstract: Disclosed herein are modified plant zinc finger proteins; compositions comprising modified plant zinc finger proteins and methods of making and using modified plant zinc finger proteins. The modified plant zinc finger proteins, in contrast to naturally-occurring plant zinc finger proteins, have a binding specificity that is determined by tandem arrays of modular zinc finger binding units.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: August 28, 2007
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Andrew Jamieson, Guofu Li
  • Publication number: 20070065931
    Abstract: Disclosed herein are modified plant zinc finger proteins; compositions comprising modified plant zinc finger proteins and methods of making and using modified plant zinc finger proteins. The modified plant zinc finger proteins, in contrast to naturally-occurring plant zinc finger proteins, have a binding specificity that is determined by tandem arrays of modular zinc finger binding unit.
    Type: Application
    Filed: October 19, 2006
    Publication date: March 22, 2007
    Inventors: Andrew Jamieson, Guofu Li
  • Publication number: 20060294617
    Abstract: Disclosed herein are modified plant zinc finger proteins; compositions comprising modified plant zinc finger proteins and methods of making and using modified plant zinc finger proteins. The modified plant zinc finger proteins, in contrast to naturally-occurring plant zinc finger proteins, have a binding specificity that is determined by tandem arrays of modular zinc finger binding unit.
    Type: Application
    Filed: August 28, 2006
    Publication date: December 28, 2006
    Inventors: Andrew Jamieson, Guofu Li
  • Publication number: 20040128717
    Abstract: Disclosed herein are modified plant zinc finger proteins; compositions comprising modified plant zinc finger proteins and methods of making and using modified plant zinc finger proteins. The modified plant zinc finger proteins, in contrast to naturally-occurring plant zinc finger proteins, have a binding specificity that is determined by tandem arrays of modular zinc finger binding units.
    Type: Application
    Filed: December 22, 2003
    Publication date: July 1, 2004
    Inventors: Andrew Jamieson, Guofu Li
  • Publication number: 20040091990
    Abstract: Disclosed herein are zinc finger proteins that bind to target sites in a plant gamma-tocopherol methyl transferase (GMT) gene; compositions comprising these GMT-targeted zinc finger proteins and methods of making and using such zinc finger proteins.
    Type: Application
    Filed: August 27, 2003
    Publication date: May 13, 2004
    Inventors: Guofu Li, Qiang Liu, Andrew Jamieson, Edward Rebar
  • Publication number: 20040091991
    Abstract: Disclosed herein are compositions and methods that regulate expression of two or more endogenous genes.
    Type: Application
    Filed: August 29, 2003
    Publication date: May 13, 2004
    Applicant: Sangamo BioSciences, Inc.
    Inventors: Jeffrey Miller, Guofu Li, Carl Pabo, Trevor Collingwood
  • Publication number: 20030233672
    Abstract: Disclosed herein are zinc finger proteins that bind to target sites in a plant gamma-tocopherol methyl transferase (GMT) gene; compositions comprising these GMT-targeted zinc finger proteins and methods of making and using such zinc finger proteins. Also disclosed are methods for modulating the alpha-tocopherol content in various plant organs, particularly seeds, in transgenic plants.
    Type: Application
    Filed: April 17, 2003
    Publication date: December 18, 2003
    Applicant: Sangamo Biosciences, Inc., a corporation
    Inventors: Guofu Li, Qiang Liu, Andrew Jamieson, Edward Rebar, Mylavarapu Venkatramesh
  • Publication number: 20030044957
    Abstract: Disclosed herein are modified plant zinc finger proteins; compositions comprising modified plant zinc finger proteins and methods of making and using modified plant zinc finger proteins. The modified plant zinc finger proteins, in contrast to naturally-occurring plant zinc finger proteins, have a binding specificity that is determined by tandem arrays of modular zinc finger binding units.
    Type: Application
    Filed: January 22, 2002
    Publication date: March 6, 2003
    Inventors: Andrew Jamieson, Guofu Li
  • Patent number: 5677331
    Abstract: The invention relates to a synergistic antimalarial composition which comprises the antimalarial agent benflumetol and also an antimalarial agent from the artemisinine group such as artemether. The composition can be formulated into solid dosage forms such as tablets and is useful for the treatment of drug resistant malaria.
    Type: Grant
    Filed: March 23, 1994
    Date of Patent: October 14, 1997
    Assignees: Ciba-Geigy AG, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences
    Inventors: Yiqing Zhou, Dianxi Ning, Shufen Wang, Deben Ding, Guofu Li, Chengqi Shan, Guangyu Liu