Abstract: A method for end-to-end speech enhancement based on a neural network, including: obtaining a time-domain smoothing feature of an original speech signal by performing feature extraction on the original speech signal using a time-domain convolution kernel; and, obtaining an enhanced speech signal by performing combined feature extraction on the original speech signal and the time-domain smoothing feature of the original speech signal.

Abstract: A rigid demolding forming device, comprising a forming cylinder (11), a dispersing box (12), a suction box (13) and a forming fabric (14), wherein the forming cylinder (11) has a rigid structure; the dispersing box (12) is arranged in the forming cylinder (11); the forming fabric (14) is externally arranged; and an absorbent material moves from inside to outside. The forming fabric (14) and the forming cylinder (11) are arranged separately, such that the forming fabric (14) can be cleaned conveniently, thereby preventing fabric holes from being blocked. In addition, the forming fabric (14) and other devices are no longer arranged in a forming hole (114), such that when a core body (15) needs to be removed from the forming hole (114) after same is formed in the forming hole (114), product defects or the waste of absorbent materials, which are caused by an electrostatic effect or a viscous force effect of devices such as the forming fabric (14), can be avoided.

Abstract: An isolated bispecific antibody or antigen-binding portion thereof includes a first chain which specifically binds to human PD-1(hPD-1) and blocks the interaction between hPD-1 and PD-L1, and a second chain which specifically binds to human CD47 and inhibits its interaction with SIRP-alpha, where the first chain and the second chain are coupled in a knob-in-hole format through their respective CH3 domain.

Abstract: An indirect selective breeding method of high-collagen meat geese includes : (1) obtaining a curve equation y=0.017x+0.026; (2) rearing goslings to young geese; (3) measuring the length, width, and height values of the knobs of the geese, and calculating to give the collagen content according to the curve equation obtained in step (1); (4) sorting the geese in descending order according to the collagen content and keeping the geese with collagen content ranked top 50% as breeding geese; (5) after the geese lay eggs, hatching the goose eggs into goslings; and (6) repeating steps (2)-(5) for selective breeding over generations. The indirect selective breeding method is simple and easy to implement. A new strain of meat geese with high collagen content can be obtained from selective breeding simply by measuring the length, width, and height of the knobs of geese of each generation.

Abstract: The present invention discloses an injection molding device for wrapping wires with three-color spiral insulation layers and three-color wires. The injection molding device comprises: a spinning block, a fixed mould, and a handpiece that are coaxially mounted. Each of the axes of these three components is provided with a center bore. The third plastic feeding pipe is arranged between the side wall of the handpiece and the center bore; a first plastic feeding pipe and a second plastic feeding pipe are arranged between the side wall of the fixed mould and the front end face thereof. This injection molding device is used to wrap wires up with three-color insulation layers. Three-color spiral wires are easy to identify and operate.