Patents by Inventor Guohong Mao

Guohong Mao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOSYNTHETIC PRODUCTION OF VARIANT STEVIOL GLYCOSIDES
    Publication number: 20210381019
    Abstract: The present invention relates to novel steviol glycosides R6-1, R6-2A, R6-2B, R6-4A, R6-4B and R7-2 and the production of these novel steviol glycosides, such as through enzymatic bioconversion. The use of these novel steviol glycosides as sweeteners and in orally consumable products are also provided.
    Type: Application
    Filed: June 11, 2021
    Publication date: December 9, 2021
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Michael Batten, Yang Luo, Oliver Yu
  • Non-caloric sweeteners and methods for synthesizing
    Patent number: 11186604
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: November 30, 2021
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • Biosynthetic production of steviol glycosides and processes therefore
    Patent number: 11098315
    Abstract: The present invention relates to the production of steviol glycoside rebaudiosides D4, WB1 and WB2 and the production of rebaudioside M from Reb D4.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: August 24, 2021
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, Yang Luo, Yilin Wu, Beihua Zhang, David Byun, Xiaodan Yu
  • BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDES REBAUDIOSIDE J AND REBAUDIOSIDE N
    Publication number: 20210189448
    Abstract: The present disclosure relates to the production of steviol glycosides rebaudioside J and rebaudioside N through the use of rebaudioside A as a substrate and a biosynthetic pathway involving various 1,2 RhaT-rhamnosyltransferases.
    Type: Application
    Filed: December 2, 2020
    Publication date: June 24, 2021
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Michael Batten, Phillip Hunt, Oliver (Xiaodan) Yu
  • Non-caloric sweetener
    Patent number: 10941174
    Abstract: Disclosed is a steviol glycoside referred to as rebaudioside D3. Rebaudioside D3 has five ?-D-glucosyl units connected to the aglycone steviol. Also disclosed are methods for producing rebaudioside D3, a UDP-glycosyltransferase fusion enzyme, and methods for producing rebaudioside D and rebaudioside E.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: March 9, 2021
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Venkata Sai Prakash Chaturvedula, Xiaodan Yu
  • BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDES AND PROCESSES THEREFORE
    Publication number: 20210002685
    Abstract: The present invention relates to the production of steviol glycoside rebaudiosides D4, WB1 and WB2 and the production of rebaudioside M from Reb D4.
    Type: Application
    Filed: June 18, 2020
    Publication date: January 7, 2021
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, David Byun, Yang Luo, Yilin Wu, Beihua Zhang, Xiaodan Yu
  • Biosynthetic production of steviol glycosides rebaudioside J and rebaudioside N
    Patent number: 10883130
    Abstract: The present disclosure relates to the production of steviol glycosides rebaudioside J and rebaudioside N through the use of rebaudioside A as a substrate and a biosynthetic pathway involving various 1,2 RhaT-rhamnosyltransferases.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: January 5, 2021
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Michael Batten, Phillip Hunt, Oliver (Xiaodan) Yu
  • NON-CALORIC SWEETENER
    Publication number: 20200361978
    Abstract: Disclosed is a steviol glycoside referred to as rebaudioside D3. Rebaudioside D3 has five ?-D-glucosyl units connected to the aglycone steviol. Also disclosed are methods for producing rebaudioside D3, a UDP-glycosyltransferase fusion enzyme, and methods for producing rebaudioside D and rebaudioside E.
    Type: Application
    Filed: April 10, 2020
    Publication date: November 19, 2020
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Venkata Sai Prakash Chaturvedula, Xiaodan Yu
  • NON-CALORIC SWEETENERS AND METHODS FOR SYNTHESIZING
    Publication number: 20200339621
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Application
    Filed: January 28, 2020
    Publication date: October 29, 2020
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • NON-CALORIC SWEETENERS AND METHODS FOR SYNTHESIZING
    Publication number: 20200331952
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Application
    Filed: February 24, 2020
    Publication date: October 22, 2020
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • Non-caloric sweeteners and methods for synthesizing
    Patent number: 10800803
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: October 13, 2020
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • HYDROLYSIS OF STEVIOL GLYCOSIDES BY BETA-GLUCOSIDASE
    Publication number: 20200291441
    Abstract: The present disclosure relates to the use of beta-glucosidase to enhance the production efficiency of desired steviol glycosides, such as rebaudioside M (reb M).
    Type: Application
    Filed: December 23, 2019
    Publication date: September 17, 2020
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, Oliver Yu
  • Non-caloric sweeteners and methods for synthesizing
    Patent number: 10774103
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: September 15, 2020
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • Production of non-caloric sweeteners using engineered whole-cell catalysts
    Patent number: 10752928
    Abstract: Disclosed are whole-cell catalysts, methods of making the whole-cell catalysts, and methods of using the whole-cell catalysts to produce steviol glycosides.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: August 25, 2020
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Shi-Yan Li, Xiaodan Yu
  • Biosynthetic production of steviol glycosides and processes therefore
    Patent number: 10724062
    Abstract: The present invention relates to the production of steviol glycoside rebaudiosides D4, WB1 and WB2 and the production of rebaudioside M from Reb D4.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: July 28, 2020
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, David Byun, Yang Luo, Yilin Wu, Beihua Zhang, Xiaodan Yu
  • Non-caloric sweetener
    Patent number: 10654881
    Abstract: Disclosed is a steviol glycoside referred to as rebaudioside D2. Rebaudioside D2 has five ?-D-glucosyl units connected to the aglycone steviol. Also disclosed are methods for producing rebaudioside D2, a UDP-glycosyltransferase fusion enzyme, and methods for producing rebaudioside D and rebaudioside E.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: May 19, 2020
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Venkata Sai Prakash Chaturvedula, Xiaodan Yu
  • BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDE REBAUDIOSIDE D4 FROM REBAUDIOSIDE E
    Publication number: 20200102588
    Abstract: The present invention relates, in some aspects, to the production of steviol glycoside rebaudioside D4 through the use of rebaudioside E. In some aspects, the invention relates to mutant CP1 enzymes, mutant HV1 enzymes as well as host cells and methods utilizing such enzymes, such as to produce rebaudioside D4.
    Type: Application
    Filed: September 6, 2019
    Publication date: April 2, 2020
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, Yang Luo, Yilin Wu, Xiaodan Yu
  • Non-caloric sweeteners and methods for synthesizing
    Patent number: 10597419
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Grant
    Filed: May 21, 2018
    Date of Patent: March 24, 2020
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • Non-caloric sweetener
    Patent number: 10597418
    Abstract: Disclosed is a steviol glycoside referred to as rebaudioside D2. Rebaudioside D2 has five ?-D-glucosyl units connected to the aglycone steviol. Also disclosed are methods for producing rebaudioside D2, a UDP-glycosyltransferase fusion enzyme, and methods for producing rebaudioside D and rebaudioside E.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: March 24, 2020
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Venkata Sai Prakash Chaturvedula, Xiaodan Yu
  • BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDES REBAUDIOSIDE J AND REBAUDIOSIDE N
    Publication number: 20200087695
    Abstract: The present disclosure relates to the production of steviol glycosides rebaudioside J and rebaudioside N through the use of rebaudioside A as a substrate and a biosynthetic pathway involving various 1,2 RhaT-rhamnosyltransferases.
    Type: Application
    Filed: November 8, 2019
    Publication date: March 19, 2020
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Michael Batten, Phillip Hunt, Oliver (Xiaodan) Yu