Abstract: An isolated bispecific antibody or antigen-binding portion thereof includes a first chain which specifically binds to human PD-1(hPD-1) and blocks the interaction between hPD-1 and PD-L1, and a second chain which specifically binds to human CD47 and inhibits its interaction with SIRP-alpha, where the first chain and the second chain are coupled in a knob-in-hole format through their respective CH3 domain.

Abstract: An improved methods and systems for detecting defect(s) on a mask are disclosed. An improved method comprises inspecting an exposed wafer after the wafer was exposed, by a lithography system using a mask, with a selected process condition that is determined based on a mask defect printability under the selected process condition; and identifying, based on the inspection, a wafer defect that is caused by a defect on the mask to enable identification of the defect on the mask.

Abstract: A method and system for configuring regenerative braking energy recovery devices in urban rail transit provided by the present application, successively including the following steps: calculating a preliminarily configured capacity Pn of a regenerative braking energy recovery device predetermined for the traction substation n, then obtaining an optimally configured capacity Qn of the regenerative braking energy recovery devices; further, configuring the total number of the regenerative braking energy recovery devices; finally, configuring the type of the regenerative braking energy recovery devices. By reasonably configure the capacity and number of regenerative braking energy recovery devices in traction substations, the configuring method of the present application allows the regenerative braking energy generated by a train during braking to be completely absorbed, thus reduce the energy consumption of braking resistors.

Abstract: The invention relates to composite floorings, more particularly to a soundproof composite flooring of magnesium sulfate and solid wood. The soundproof composite flooring includes a paint layer, a solid wood layer, a magnesium sulfate substrate layer, and a soundproof layer which are sequentially arranged from top to bottom; the solid wood layer and the magnesium sulfate substrate layer are bonded via AB glue by cold pressing or via a hot-melt adhesive; a plurality of cylindrical holes are arranged along edges of an upper surface of the magnesium sulfate substrate layer, and a buffer structure is arranged in each of the cylindrical holes; the buffer structure includes a rubber base which fits a bottom of the cylindrical holes, and a support disk which is opposite to the solid wood layer. The rubber base and the support disk are connected by a rubber column.

Abstract: A method and system for configuring regenerative braking energy recovery devices in urban rail transit provided by the present application, successively including the following steps: calculating a preliminarily configured capacity Pn of a regenerative braking energy recovery device predetermined for the traction substation n, then obtaining an optimally configured capacity Qn of the regenerative braking energy recovery devices; further, configuring the total number of the regenerative braking energy recovery devices; finally, configuring the type of the regenerative braking energy recovery devices. By reasonably configure the capacity and number of regenerative braking energy recovery devices in traction substations, the configuring method of the present application allows the regenerative braking energy generated by a train during braking to be completely absorbed, thus reduce the energy consumption of braking resistors.

Abstract: The invention relates to composite floorings, more particularly to a soundproof composite flooring of magnesium sulfate and solid wood. The soundproof composite flooring includes a paint layer, a solid wood layer, a magnesium sulfate substrate layer, and a soundproof layer which are sequentially arranged from top to bottom; the solid wood layer and the magnesium sulfate substrate layer are bonded via AB glue by cold pressing or via a hot-melt adhesive; a plurality of cylindrical holes are arranged along edges of an upper surface of the magnesium sulfate substrate layer, and a buffer structure is arranged in each of the cylindrical holes; the buffer structure includes a rubber base which fits a bottom of the cylindrical holes, and a support disk which is opposite to the solid wood layer. The rubber base and the support disk are connected by a rubber column.

Abstract: A method for fast detecting pavement asphalt and early warning based on infrared spectrum data. Infrared spectrum data of standard sample asphalt is collected by adopting an infrared spectrometer, to establish an infrared spectrum database of standard sample asphalt. The infrared spectrum database of the standard sample asphalt and basic asphalt information is introduced into a cloud server through a spectrum input module. A database-matching calculation method and a threshold value is set through a spectrum-matching analysis module. The infrared spectrum data and engineering information of the tested asphalt is collected and uploaded to a cloud platform for storage. A matching calculation between the uploaded data and the spectrograms in the infrared spectrum database of the standard sample asphalt through the cloud server is conducted. An asphalt matching result is outputted to a display terminal. An early-warning message is pushed by the cloud server if a test result is not-match.

Abstract: A text mining-based attribute analysis method for Internet media users comprises a first steps of establishing a label main corpus and a feature corpus sequentially, and updating and maintaining the label main corpus and the feature corpus respectively, and a second step of extracting all history article samples of Internet users, and cleaning out videos, audios and pictures in the samples. The text mining-based attribute analysis method can form attributes of browsed sample articles for each Internet media user, and analyze accurately weights of interesting categories, to identify deeply, analyze, and mine the user attributes, and the basic attributes of the Internet users can also be analyzed.

Abstract: A method for fast detecting pavement asphalt and early warning based on infrared spectrum data. Infrared spectrum data of standard sample asphalt is collected by adopting an infrared spectrometer, to establish an infrared spectrum database of standard sample asphalt. The infrared spectrum database of the standard sample asphalt and basic asphalt information is introduced into a cloud server through a spectrum input module. A database-matching calculation method and a threshold value is set through a spectrum-matching analysis module. The infrared spectrum data and engineering information of the tested asphalt is collected and uploaded to a cloud platform for storage. A matching calculation between the uploaded data and the spectrograms in the infrared spectrum database of the standard sample asphalt through the cloud server is conducted. An asphalt matching result is outputted to a display terminal. An early-warning message is pushed by the cloud server if a test result is not-match.

Abstract: A text mining-based attribute analysis method for Internet media users comprises a first steps of establishing a label main corpus and a feature corpus sequentially, and updating and maintaining the label main corpus and the feature corpus respectively, and a second step of extracting all history article samples of Internet users, and cleaning out videos, audios and pictures in the samples. The text mining-based attribute analysis method can form attributes of browsed sample articles for each Internet media user, and analyze accurately weights of interesting categories, to identify deeply, analyze, and mine the user attributes, and the basic attributes of the Internet users can also be analyzed.

Abstract: Merging sub-resolution assist features includes receiving a mask pattern that includes the sub-resolution assist features. A first sub-resolution assist feature is selected to merge with a second sub-resolution assist feature. A merge bar width of a merge bar is established. A distance between the first sub-resolution assist feature and the second sub-resolution assist feature is determined. A merging technique is determined in accordance with the distance and the merge bar width. The first sub-resolution assist feature and the second sub-resolution assist feature are merged according to the identified merging technique.

Abstract: Merging sub-resolution assist features includes receiving a mask pattern that includes the sub-resolution assist features. A first sub-resolution assist feature is selected to merge with a second sub-resolution assist feature. A merge bar width of a merge bar is established. A distance between the first sub-resolution assist feature and the second sub-resolution assist feature is determined. A merging technique is determined in accordance with the distance and the merge bar width. The first sub-resolution assist feature and the second sub-resolution assist feature are merged according to the identified merging technique.

Abstract: Merging sub-resolution assist features includes receiving a mask pattern that includes the sub-resolution assist features. A first sub-resolution assist feature is selected to merge with a second sub-resolution assist feature. A merge bar width of a merge bar is established. A distance between the first sub-resolution assist feature and the second sub-resolution assist feature is determined. A merging technique is determined in accordance with the distance and the merge bar width. The first sub-resolution assist feature and the second sub-resolution assist feature are merged according to the identified merging technique.

Abstract: The present application is directed to a method for determining photolithography focus errors during production of a device. The method comprises providing a substrate and forming a photoresist pattern on the substrate. The photoresist pattern comprises a device pattern and one or more blocking scheme patterns. The process further comprises performing a device manufacturing process using the photoresist pattern as a mask to form sensor windows on the substrate. One or more focus error sensors are formed in the sensor windows. Focus errors are determined using the focus error sensors. Other embodiments of the present application are directed to wafers comprising one or more focus error sensors positioned in sensor windows.

Abstract: Merging sub-resolution assist features includes receiving a mask pattern that includes the sub-resolution assist features. A first sub-resolution assist feature is selected to merge with a second sub-resolution assist feature. A merge bar width of a merge bar is established. A distance between the first sub-resolution assist feature and the second sub-resolution assist feature is determined. A merging technique is determined in accordance with the distance and the merge bar width. The first sub-resolution assist feature and the second sub-resolution assist feature are merged according to the identified merging technique.

Abstract: Merging sub-resolution assist features includes receiving a mask pattern that includes the sub-resolution assist features. A first sub-resolution assist feature is selected to merge with a second sub-resolution assist feature. A merge bar width of a merge bar is established. A distance between the first sub-resolution assist feature and the second sub-resolution assist feature is determined. A merging technique is determined in accordance with the distance and the merge bar width. The first sub-resolution assist feature and the second sub-resolution assist feature are merged according to the identified merging technique.

Abstract: The present application is directed to a method for determining photolithography focus errors during production of a device. The method comprises providing a substrate and forming a photoresist pattern on the substrate. The photoresist pattern comprises a device pattern and one or more blocking scheme patterns. The process further comprises performing a device manufacturing process using the photoresist pattern as a mask to form sensor windows on the substrate. One or more focus error sensors are formed in the sensor windows. Focus errors are determined using the focus error sensors. Other embodiments of the present application are directed to wafers comprising one or more focus error sensors positioned in sensor windows.

Abstract: According to one embodiment of the invention, a method for enhancing multiple feature lithography is provided. The method includes generating a plurality of maps each associated with a particular one of a plurality of circuit features. Each map maps an illumination field comprising a plurality of point sources and indicates, in terms of a process metric and for each point source, a level of feature quality that will result from using the each point source to image the each circuit feature. The method also includes identifying, based on the maps, a group of one or more of the point sources that, if used to image the circuit features onto a target surface, will result in an overall feature quality level equal to or greater than a predetermined quality threshold.

Abstract: According to one embodiment, a method for patterning a set of features for a semiconductor device includes providing a mask including a substrate and at least one pair of first and second main features disposed on a substrate. The method also includes positioning the mask over a layer of light-sensitive material, and exposing the mask to a light source. The mask also includes at least one sub-resolution feature connecting the first and second main features.