Abstract: The present disclosure relates to a microchannel-based method for obtaining the mechanical modulus of a cell, a microchannel-based jet stream control method, an apparatus, an electronic device, and a storage medium. The microchannel-based jet stream control method includes: obtaining the mechanical modulus of a cell before the cell enters a jet stream region of a microchannel; and adjusting the intensity of a jet stream originated from a jet stream apparatus and used to perforate the cell based on the mechanical modulus of the cell, so that the cell membrane tension of the cell is between a perforation threshold and a rupture threshold. According to the technical solution of the present disclosure, the cell transduction rate, the cell throughput, and the cell survival rate can be improved.

Abstract: A cleansing bar, comprising: 5 to 50% by weight soap and free fatty acid, based on the total weight of the cleansing bar, comprising 30 to 50% by weight free fatty acid based on the total weight of the cleansing bar and 0 to 16% by weight soap based on the total weight of the cleansing bar; wherein the weight ratio of free fatty acid:soap is greater than 1:1; 10 to 25% by weight non-soap synthetic surfactants, based on the total weight of the cleansing bar; 9 to 50% by weight zeolite, based on the total weight of the cleansing bar; and 10 to 30% by weight water, based on the total weight of the cleansing bar; wherein a pH of the cleansing bar measured from an 8% by weight bar slurry is 4.5 to 10. The bars are produced via a high-speed extrusion process without negatives (e.g., free of grittiness, cracking, etc.) while retaining good user properties (e.g., lather).

Abstract: A smooth cooperative lane change control method for multi-connected and autonomous vehicles (CAVs), including: acquiring vehicle information of a lane-changing vehicle M and four surrounding vehicles A, B, C and D; constructing uncontrolled-vehicle and controlled-vehicle motion state prediction models; according to the motion state prediction models, predicting motion states of the lane-changing vehicle M, and the vehicles A, B, C and D; constructing an upper-layer optimization model to calculate an optimal control value and an optimized motion state of the lane-changing vehicle M and an optimal control value of the vehicle A; constructing a lower-layer optimization model to calculate an optimal control value of the vehicle D; and controlling the lane-changing vehicle M, the vehicle A and the vehicle D to run according to a corresponding optimal control value.

Abstract: The invention relates to bar composition comprising minimum floor levels of C10 soap while minimizing ratio of unsaturated C18 soap to caprate. Such bars provide enhanced rapid, antibacterial activity. Disclosed is a soap bar composition comprising: a) 25 to 85%, preferably 35 to 75% by weight of C8 to C24 fatty acid soap comprising: (i) C10 soap at 8% or 15% or greater, more preferably 16 to 32% by weight of total bar composition; and, (ii) unsaturated C18 soap, wherein weight ratio of said unsaturated C18 soap to C10 (caprate) soap is 1.2 to 0.1. b) 1 to 45% organic and inorganic adjuvant materials by weight of the composition; and, c) 5 to 30%, preferably 13 to 28% water by weight of the composition, wherein excess of C10 soap to unsaturated C18 soap is at least 6%.

Abstract: This invention relates to syndet-based compositions having pH of 4.5 to 5.5 wherein use of caprylic acid has been unexpectedly found to enhance bacterial kill.

Abstract: The present invention discloses an FXR (farnesoid X receptor) small molecule agonist, the structure of which is shown in formula I, and a preparation method thereof. In the formula, the definition of each substituent is as described in the specification and claims. The compound of the present invention has advantages, such as high FXR agonistic activity, convenience in synthesis, easy availability of raw materials, and can be used as a medicine for the treatment of FXR-related diseases.

Abstract: This invention relates to syndet-based compositions having pH of 4.5 to 5.5 wherein use of caprylic acid has been unexpectedly found to enhance bacterial kill.

Abstract: This invention relates to syndet-based compositions having pH of 4.5 to 5.5 wherein use of caprylic acid has been unexpectedly found to enhance bacterial kill.

Abstract: The present invention relates to an extruded bar soap composition. It more particularly relates to a soap bar composition which exhibits better bloom (perfume impact) and better deposition of actives as compared to conventional soap bars. This is obtained by ensuring that the amount of oleate soap is kept low while incorporating some amount of ricinoleate soap.

Abstract: A computing device selects a trained spatial regression model. A spatial weights matrix defined for observation vectors is selected, where each element of the spatial weights matrix indicates an amount of influence between respective pairs of observation vectors. Each observation vector is spatially referenced. A spatial regression model is selected from spatial regression models, initialized, and trained using the observation vectors and the spatial weights matrix to fit a response variable using regressor variables. Each observation vector includes a response value for the response variable and a regressor value for each regressor variable of the regressor variables. A fit criterion value is computed for the spatial regression model and the spatial regression model selection, initialization, and training are repeated until each spatial regression model is selected. A best spatial regression model is selected and output as the spatial regression model having an extremum value of the fit criterion value.

Abstract: The invention relates to bar composition comprising minimum floor levels of C10 soap while minimizing ratio of unsaturated C18 soap to caprate. Such bars provide enhanced rapid, antibacterial activity. Disclosed is a soap bar composition comprising: a) 25 to 85%, preferably 35 to 75% by weight of C8 to C24 fatty acid soap comprising: (i) C10 soap at 8% or 15% or greater, more preferably 16 to 32% by weight of total bar composition; and, (ii) unsaturated C18 soap, wherein weight ratio of said unsaturated C18 soap to C10 (caprate) soap is 1.2 to 0.1. b) 1 to 45% organic and inorganic adjuvant materials by weight of the composition; and, c) 5 to 30%, preferably 13 to 28% water by weight of the composition, wherein excess of C10 soap to unsaturated C18 soap is at least 6%.

Abstract: The present invention relates to an extruded bar soap composition. It more particularly relates to a soap bar composition which exhibits better bloom (perfume impact) and better deposition of actives as compared to conventional soap bars. This is obtained by ensuring that the amount of oleate soap is kept low while incorporating some amount of ricinoleate soap.

Abstract: This invention relates to syndet-based compositions having pH of 4.5 to 5.5 wherein use of caprylic acid has been unexpectedly found to enhance bacterial kill.

Abstract: Webpage loading methods and devices include, in addition to sending an address of a first webpage to a server, a client further sends a name of a first-webpage resource stored in the client, such that the server can determine, according to the address of the first webpage and the name of the first-webpage resource stored in the client, a first push resource to be sent to the client, where the first push resource is all the resources required for loading the first webpage apart from the first-webpage resource stored in the client, which avoids pushing, by the server to the client, a resource that has been locally stored in the client, and therefore saves a bandwidth resource of a communications network.

Abstract: The present invention relates to an antimicrobial composition comprising polyvalent metal salt of pyrithione; 0.001% to 3% by weight thymol, and 0.001% to 3% by weight terpineol; wherein, the ratio of % weight of polyvalent metal salt of pyrithione to sum of % weight of thymol and terpineol ranges from 0.005:1 to 200:1.

Abstract: A soap bar comprising: (a) 25 to 85% by weight, based on the total weight of the bar, of fatty acid soap; (b) 0.1 to 100 ppm by weight, based on the total weight of the bar, of at least one silver (I) compound having a selected silver ion solubility, wherein at 25° C., a 1 wt % solution of the bar in water has a pH of from 9 to 11.

Abstract: Webpage loading methods and devices include, in addition to sending an address of a first webpage to a server, a client further sends a name of a first-webpage resource stored in the client, such that the server can determine, according to the address of the first webpage and the name of the first-webpage resource stored in the client, a first push resource to be sent to the client, where the first push resource is all the resources required for loading the first webpage apart from the first-webpage resource stored in the client, which avoids pushing, by the server to the client, a resource that has been locally stored in the client, and therefore saves a bandwidth resource of a communications network.

Abstract: Webpage loading methods and devices include, in addition to sending an address of a first webpage to a server, a client further sends a name of a first-webpage resource stored in the client, such that the server can determine, according to the address of the first webpage and the name of the first-webpage resource stored in the client, a first push resource to be sent to the client, where the first push resource is all the resources required for loading the first webpage apart from the first-webpage resource stored in the client, which avoids pushing, by the server to the client, a resource that has been locally stored in the client, and therefore saves a bandwidth resource of a communications network.

Abstract: Method of cleansing human skin employing an aqueous soap composition comprising of fatty acid soap, at least one silver (I) compound having a silver ion solubility (in water at 25° C.) of at least 1×10?4 mol/L, and water, which composition provides biocidal activity against Gram positive bacteria in particular S. aureus, in relatively short contact periods.

Abstract: The present invention relates to an antimicrobial composition comprising 1% to 90% by weight surfactant; a polyvalent metal salt of pyrithione; 0.001 to 3% by weight thymol, and 0.001 to 3% by weight terpineol.