Abstract: A communication method comprises that if a policy control device does not support setup of an Internet Protocol (IP) multimedia subsystem (IMS) default bearer during setup of an IMS default bearer for a terminal, the control plane gateway sends second indication information to a user plane gateway, where the second indication information indicates the control plane gateway bypasses the policy control device. When the user plane gateway receives an IMS session request from the terminal and determines that the control plane gateway bypasses the policy control device, the user plane gateway sends first indication information to the control plane gateway, and the first indication information indicates the control plane gateway to send, to the policy control device, a first request to request to establish a mapping relationship between the terminal and the control plane gateway such that an IMS session can be set up between terminals.

Abstract: A high aspect ratio in-plane metal microneedle array, a manufacturing method and a clamping and inserting auxiliary device thereof is disclosed. A large-size metal sheet is cut into small metal sheets. A clamping tooling composed of two upper and lower metal cover plates is processed. Inner sides of the upper and the lower cover plates of the tooling are provided with grooves in which the metal sheets are placed and fastened by bolts. Wire cutting is conducted on the tooling and the metal sheets as a whole to obtain a plane metal microneedle array with a plurality of microneedle bodies. In addition, an assembling and clamping device and an inserting auxiliary device of the high aspect ratio in-plane metal microneedle array is provided. The assembled inserting auxiliary device is placed on skin, and the microneedle array is inserted into the skin through the auxiliary device.

Abstract: An automatic righting system includes a discrimination calibration module, a righting module, and a controller. The discrimination calibration module includes a distance sensing unit. The distance sensing unit is located at the front end of the glasses and configured to acquire the distance between the distance sensing unit and a first feature position. The righting module includes a push-up air cushion. The push-up air cushion is mounted at the front end of the glasses. The push-up air cushion is configured to be inflated to push the glasses to move upward. The controller is electrically connected to the distance sensing unit and the push-up air cushion. The controller is configured to control the push-up air cushion to start or stop to right the glasses according to a distance signal of the distance sensing unit.

Abstract: This application relates to a hard-shell inclusion strain gauge for 3D stress in surrounding rockmass of underground engineering. The hard-shell inclusion strain gauge comprises an elastic cylinder and at least three sets of strain rosettes, wherein the elastic cylinder is installed in a borehole of underground engineering, and at least three sets of strain rosettes are equidistant along the circumference on the inner wall of the elastic cylinder. It can accurately measure strain values and variables of each strain rosette through data collection and transmission module, and calculate 3D stress in surrounding rock of underground engineering. It can obtain dynamic long-term monitoring of 3D stress evolution in complex environments of underground engineering, truly reflecting the real-time state, the spatial distribution, and the evolution of 3D stress in rockmass, and provide in-situ basic data for engineering disaster warning and control.

Abstract: The present disclosure relates to a fiber mix formulation comprising a mixture of bran, inulin, and digestion resistant maltodextrin useful to restore a healthier gut microbiota and alleviate symptoms in subjects with imbalance of gut microbiota. The mixture of soluble dietary fiber (SDF) and insoluble dietary fiber (ISDF) with a ratio of ISDF:SDF (0.5:1 to 1:0.5), has synergistic effect on gut microbiota composition, promoting the growth of the acetate- and butyrate-producing bacteria and inhibiting the growth of pathogens and detrimental bacteria.

Abstract: This invention relates to novel probiotic Bifidobacteria strains, particularly, B. pseudocatenulatum strains, and their use as probiotic, and food products, feed products, dietary supplements and pharmaceutical formulations containing them. The bacteria are suitable for the treatment of obesity, diabetes, and related conditions.

Abstract: A communication method comprises that if a policy control device does not support setup of an Internet Protocol (IP) multimedia subsystem (IMS) default bearer during setup of an IMS default bearer for a terminal, the control plane gateway sends second indication information to a user plane gateway, where the second indication information indicates the control plane gateway bypasses the policy control device. When the user plane gateway receives an IMS session request from the terminal and determines that the control plane gateway bypasses the policy control device, the user plane gateway sends first indication information to the control plane gateway, and the first indication information indicates the control plane gateway to send, to the policy control device, a first request to request to establish a mapping relationship between the terminal and the control plane gateway such that an IMS session can be set up between terminals.

Abstract: A method comprises: obtaining historical vehicle service data in an area for a time period including historical locations of passenger-seeking vehicles with respect to time, historical locations of passenger orders with respect to time, and historical trip fares with respect to pick-up locations and time; discretizing the area into a plurality of zones and discretizing the time period into a plurality of time segments; aggregating the historical vehicle service data according the zones and time segments; obtaining an expected reward for a passenger-seeking vehicle to move from zone A to each neighboring zone of the zone A based on the aggregated historical vehicle service data; and obtaining a probability of a passenger-seeking vehicle moving from zone A to a neighboring zone B based on the expected reward for the passenger-seeking vehicle to move from zone A to the each neighboring zone of the zone A.

Abstract: The present invention provides a method for assessing the presence or the risk of development of type 2 diabetes mellitus in a subject based on abundance data of several CAGs. Also provided is a method for evaluating efficacy of diet intervention or disease treatment in a subject having type 2 diabetes mellitus based on abundance data of these CAGs.

Abstract: A method comprises: obtaining historical vehicle service data in an area for a time period including historical locations of passenger-seeking vehicles with respect to time, historical locations of passenger orders with respect to time, and historical trip fares with respect to pick-up locations and time; discretizing the area into a plurality of zones and discretizing the time period into a plurality of time segments; aggregating the historical vehicle service data according the zones and time segments; obtaining an expected reward for a passenger-seeking vehicle to move from zone A to each neighboring zone of the zone A based on the aggregated historical vehicle service data; and obtaining a probability of a passenger-seeking vehicle moving from zone A to a neighboring zone B based on the expected reward for the passenger-seeking vehicle to move from zone A to the each neighboring zone of the zone A.

Abstract: This invention relates to novel probiotic Bifidobacteria strains, particularly, B. pseudocatenulatum strains, and their use as probiotic, and food products, feed products, dietary supplements and pharmaceutical formulations containing them. The bacteria are suitable for the treatment of obesity, diabetes, and related conditions.

Abstract: Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject.

Abstract: Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject.

Abstract: Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject.

Abstract: A heartbeat-based data synchronization method is disclosed. The method is applied to a distributed storage system, and at least one data block group is stored in the distributed storage system. The distributed storage system includes multiple storage devices, one device in the multiple storage devices is a primary device for storing the data block group, and other devices are secondary devices for storing the data block group. The primary device performs the method. The primary device obtains access status information of the data block group, determines a heartbeat time of the data block group according to the access status information of the data block group, and sends a data synchronization instruction to the secondary device according to the heartbeat time of the data block group, where the data synchronization instruction is used to instruct the secondary device to synchronize data.

Abstract: This invention relates to novel probiotic Bifidobacteria strains, particularly, a B. pseudocatenulatum strain, and its use as probiotic, and food products, feed products, dietary supplements and pharmaceutical formulations containing them. The bacteria are suitable for the treatment of obesity, diabetes (particularly Type 2 diabetes), and related conditions.

Abstract: A heartbeat-based data synchronization method is disclosed. The method is applied to a distributed storage system, and at least one data block group is stored in the distributed storage system. The distributed storage system includes multiple storage devices, one device in the multiple storage devices is a primary device for storing the data block group, and other devices are secondary devices for storing the data block group. The primary device performs the method. The primary device obtains access status information of the data block group, determines a heartbeat time of the data block group according to the access status information of the data block group, and sends a data synchronization instruction to the secondary device according to the heartbeat time of the data block group, where the data synchronization instruction is used to instruct the secondary device to synchronize data.

Abstract: Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject.