Patents by Inventor Guokai Chen

Guokai Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230287049
    Abstract: A venom-based peptide and an application thereof, which relate to the technical field of biomolecules. The amino acid sequence of the peptide is represented by formula 1: X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-X12-X13-X14-X15-X16-X17-X18; X1, X5, X6, X9 and X11 are each selected from any one among A, V, L, I, M, F, W and P; X2, X3, X10, X15, X17 and X18 are each selected from any one among G, C, S, T, Y, N and Q; X7 is selected from D or E; X4, X8 and X16 are each selected from any one among K, R and H; and X12, X13 and X14 are each selected from any one among K, R, H, D and E. The peptide has the function of promoting self-renewal of human embryonic stem cells.
    Type: Application
    Filed: July 21, 2020
    Publication date: September 14, 2023
    Inventors: Hang Fai KWOK, Rui MA, Guokai CHEN
  • Patent number: 11579446
    Abstract: Provided are an augmented reality optical module, including a first lens, a second lens, a third lens group, a first polarization modulation unit provided on a side of the third lens group and configured to modulate the light emitted by the image source into first circularly polarized light, an angle selection film provided on a first surface of one side of the first lens and configured to reflect light having an incidence angle greater than or equal to a first angle and transmit light having an incidence angle smaller than or equal to a second angle, and a second polarization modulation unit provided on the other side of the first lens and configured to modulate incident circularly polarized light into linearly polarized light.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: February 14, 2023
    Assignee: SeeYA Optronics Co., Ltd.
    Inventors: Guokai Chen, Liu Lu, Qiu Sunjie, Niu Lei, Liu Bo
  • Patent number: 11543660
    Abstract: An augmented reality optical module includes a relay lens group and a reflection lens group. The relay lens group receives and converges the light emitted by the image source. The reflection lens group comprises a first lens and a second lens. The light emitted by the image source is incident to the relay lens group and converged to form the relay image at least once, the light of the last relay image is incident to a first surface of the first lens and reflected, the reflected light is incident to a first surface of the second lens and reflected, and then incident to the first lens and transmitted through the first lens to form imaging light. The ambient light is transmitted in such a manner that the ambient light is transmitted through the second lens and the first lens, sequentially, and then emitted to be superimposed on the imaging light.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: January 3, 2023
    Assignee: SeeYA Optronics Co., Ltd.
    Inventors: Guokai Chen, Lu Liu, Sunjie Qiu, Lei Niu, Bo Liu
  • Publication number: 20210199969
    Abstract: An augmented reality optical module includes a relay lens group and a reflection lens group. The relay lens group receives and converges the light emitted by the image source. The reflection lens group comprises a first lens and a second lens. The light emitted by the image source is incident to the relay lens group and converged to form the relay image at least once, the light of the last relay image is incident to a first surface of the first lens and reflected, the reflected light is incident to a first surface of the second lens and reflected, and then incident to the first lens and transmitted through the first lens to form imaging light. The ambient light is transmitted in such a manner that the ambient light is transmitted through the second lens and the first lens, sequentially, and then emitted to be superimposed on the imaging light.
    Type: Application
    Filed: August 27, 2020
    Publication date: July 1, 2021
    Inventors: Guokai Chen, Lu Liu, Sunjie Qiu, Lei Niu, Bo Liu
  • Publication number: 20210199962
    Abstract: Provided are an augmented reality optical module, including a first lens, a second lens, a third lens group, a first polarization modulation unit provided on a side of the third lens group and configured to modulate the light emitted by the image source into first circularly polarized light, an angle selection film provided on a first surface of one side of the first lens and configured to reflect light having an incidence angle greater than or equal to a first angle and transmit light having an incidence angle smaller than or equal to a second angle, and a second polarization modulation unit provided on the other side of the first lens and configured to modulate incident circularly polarized light into linearly polarized light.
    Type: Application
    Filed: August 27, 2020
    Publication date: July 1, 2021
    Inventors: GUOKAI CHEN, LIU LU, QIU SUNJIE, NIU LEI, LIU BO
  • Patent number: 9771556
    Abstract: Vitronectin-derived cell culture substrates and methods of using the same for culturing pluripotent stem cells are presented. Also provided herein are defined culture systems for maintaining human pluripotent stem cells in a substantially undifferentiated state, where the defined culture system comprises human pluripotent stem cells, a defined culture medium, and at least one polypeptide selected from the group consisting of residues 43 to 378 of SEQ ID NO:1 and residues 45 to 378 of SEQ ID NO:1, and where the defined culture medium comprises insulin, selenium, transferrin, L-ascorbic acid, FGF2, DMEM/F12, NaHCO3, and one of TGF? and NODAL.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: September 26, 2017
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James A. Thomson, Zhonggang Hou, Guokai Chen
  • Patent number: 9644186
    Abstract: Fully defined media that support pluripotent cell viability, proliferation, cloning, and derivation, as well as methods and compositions including these media are described. Methods for deriving iPS cells from adult individuals under defined, xeno-free conditions are also described.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: May 9, 2017
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Guokai Chen, James A. Thomson
  • Publication number: 20160340652
    Abstract: Media for the culture of pluripotent stem cells and differentiation of cardiomyocytes, and methods of using this media to produce cardiomyocytes. These media and methods can support cloning, differentiation and induced pluripotent stem (iPS) cell derivation.
    Type: Application
    Filed: May 20, 2016
    Publication date: November 24, 2016
    Inventors: Guokai Chen, Yongshun Lin
  • Publication number: 20160230143
    Abstract: The present invention is directed to a low protein medium for the culture of pluripotent stem cells comprising one or more polysaccharides. The medium of the present invention can support cell culture objectives, for example cell survival, maintenance, passaging, proliferation, pluripotency, cloning, differentiation and induced pluripotent stem (iPS) cell derivation.
    Type: Application
    Filed: September 19, 2014
    Publication date: August 11, 2016
    Inventors: Guokai CHEN, Yongshun LIN
  • Publication number: 20160194611
    Abstract: Fully defined media that support pluripotent cell viability, proliferation, cloning, and derivation, as well as methods and compositions including these media are described. Methods for deriving iPS cells from adult individuals under defined, xeno-free conditions are also described.
    Type: Application
    Filed: March 7, 2016
    Publication date: July 7, 2016
    Inventors: Guokai Chen, James A. Thomson
  • Patent number: 9340771
    Abstract: Methods are provided that exploit thermostable FGF-1 proteins for support of human pluripotent stem cell cultures. Also provided are compositions containing thermostable FGF-1 for culturing of human pluripotent stem cells.
    Type: Grant
    Filed: May 4, 2015
    Date of Patent: May 17, 2016
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Guokai Chen, James A. Thomson
  • Patent number: 9279107
    Abstract: Fully defined media that support pluripotent cell viability, proliferation, cloning, and derivation, as well as methods and compositions including these media are described. Methods for deriving iPS cells from adult individuals under defined, xeno-free conditions are also described.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: March 8, 2016
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Guokai Chen, James A. Thomson
  • Patent number: 9279103
    Abstract: Fully defined media that support pluripotent cell viability, proliferation, cloning, and derivation, as well as methods and compositions including these media are described. Methods for deriving iPS cells from adult individuals under defined, xeno-free conditions are also described.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: March 8, 2016
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Guokai Chen, James A. Thomson
  • Publication number: 20150368610
    Abstract: Vitronectin-derived cell culture substrates and methods of using the same for culturing pluripotent stem cells are presented.
    Type: Application
    Filed: August 5, 2015
    Publication date: December 24, 2015
    Inventors: James A. Thomson, Zhonggang Hou, Guokai Chen
  • Publication number: 20150267166
    Abstract: Methods are provided that exploit thermostable FGF-1 proteins for support of human pluripotent stem cell cultures. Also provided are compositions containing thermostable FGF-1 for culturing of human pluripotent stem cells.
    Type: Application
    Filed: May 4, 2015
    Publication date: September 24, 2015
    Inventors: Guokai Chen, James A. Thomson
  • Patent number: 9133266
    Abstract: Vitronectin-derived cell culture substrates and methods of using the same for culturing pluripotent stem cells are presented.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: September 15, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James A. Thomson, Zhonggang Hou, Guokai Chen
  • Patent number: 9023644
    Abstract: Methods are provided that exploit thermostable FGF-1 proteins for support of human pluripotent stem cell cultures. Also provided are compositions containing thermostable FGF-1 for culturing of human pluripotent stem cells.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: May 5, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Guokai Chen, James A. Thomson
  • Patent number: 8772460
    Abstract: Thermostable FGF-2 proteins having enhanced ability to support human pluripotent stem cell cultures are provided. Also provided are methods and compositions utilizing thermostable FGF-2 proteins.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: July 8, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Guokai Chen, James A. Thomson, Zhonggang Hou
  • Publication number: 20130236959
    Abstract: Thermostable FGF-2 proteins having enhanced ability to support human pluripotent stem cell cultures are provided. Also provided are methods and compositions utilizing thermostable FGF-2 proteins.
    Type: Application
    Filed: December 17, 2012
    Publication date: September 12, 2013
    Inventors: Guokai Chen, James A. Thomson, Zhonggang Hou
  • Publication number: 20130157359
    Abstract: Methods are provided that exploit thermostable FGF-1 proteins for support of human pluripotent stem cell cultures. Also provided are compositions containing thermostable FGF-1 for culturing of human pluripotent stem cells.
    Type: Application
    Filed: December 17, 2012
    Publication date: June 20, 2013
    Inventors: Guokai Chen, James A. Thomson