Patents by Inventor Guokai ZHANG

Guokai ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240034755
    Abstract: Disclosed are a self-assembled nanoparticle containing a gB protein of an EB virus and a preparation method and use thereof The self-assembled nanoparticle comprises a first polypeptide and a second polypeptide; the first polypeptide comprises the gB protein and a first vector subunit, the second polypeptide comprises a second vector subunit; the first vector subunit is I53-50A1, and the second vector subunit is I53-50B.4PT1. In the self-assembled nanoparticle provided herein, the gB protein of the EB virus is displayed on the surface of the nanoparticle for the first time. The particle size of the self-assembled nanoparticle is larger than that of the antigen gB, and the chemical stability of the self-assembled nanoparticle is higher than that of the antigen gB, and the binding capacity with the neutralizing antibody of the self-assembled nanoparticle are higher than that of the antigen gB.
    Type: Application
    Filed: December 16, 2020
    Publication date: February 1, 2024
    Inventors: Musheng ZENG, Cong SUN, Yixin ZENG, Guokai FENG, Yinfeng KANG, Xinchun CHEN, Xiao ZHANG, Qianying ZHU, Jiangping LI, Xiangwei KONG
  • Publication number: 20240037378
    Abstract: Systems, apparatuses and methods may provide for technology that identifies an embedding table associated with a neural network. The neural network is associated with a plurality of compute nodes. The technology further identifies a number of entries of the embedding table, and determines whether to process gradients associated with the embedding table as dense gradients or sparse gradients based on the number of entries.
    Type: Application
    Filed: December 24, 2020
    Publication date: February 1, 2024
    Applicant: Intel Corporation
    Inventors: Guokai Ma, Jiong Gong, Dhiraj Kalamkar, Rachitha Prem Seelin, Hongzhen Liu, Akshay Jain, Liangang Zhang
  • Publication number: 20230286049
    Abstract: A device and a method for controlling a size of a molten pool in a wire and arc additive manufacturing process are provided. The device includes additive manufacturing equipment, a connecting device, bilateral gas flow devices and a CCD camera. By adjusting the connecting device, the bilateral gas flow devices and a welding gun have proper relative positions. The CCD camera is clamped on a rear side of the welding gun and matched with a proper optical filter to detect size information of the molten pool. In the additive manufacturing process, the bilateral gas flow devices and the welding gun keep moving synchronously, welding wires are conveyed to a designed position of a deposited layer by a wire feeding device, and bilateral gas flows can directly and synchronously act on a melting region. A flow controller is adjusted in real time according to the size of the molten pool.
    Type: Application
    Filed: March 10, 2023
    Publication date: September 14, 2023
    Applicant: Beijing University of Technology
    Inventors: Fan JIANG, Guokai ZHANG, Bin XU, Debao LI, Shujun CHEN
  • Publication number: 20210251708
    Abstract: A surgical robot mechanism with single-port and multi-port minimally invasive surgery functions includes: a bracket; and a manipulator connected to the bracket, and supported by the bracket, the manipulator includes: a support arm movable along the bracket; a function conversion frame fixed on the support arm and configured for the surgical robot mechanism to switch between a single-port minimally invasive surgery mode and a multi-port minimally invasive surgery mode; a plurality of posture adjustment arm assemblies connected to the function conversion frame, each posture adjustment arm assembly configured to adjust a position and posture of a surgical tool connected thereto for performing a surgical operation.
    Type: Application
    Filed: October 25, 2018
    Publication date: August 19, 2021
    Applicant: TIANJIN UNIVERSITY
    Inventors: Shuxin WANG, Zhenxuan HU, Guokai ZHANG, Dezhong GAO, Jianmin LI, Jinhua LI
  • Publication number: 20210000460
    Abstract: A sponge-based variable-stiffness support structure for natural orifice surgical instrument is to support the surgical instrument and includes: a variable-stiffness sponge pipeline connected with the natural orifice surgical instrument and configured to support the natural orifice surgical instrument in a natural orifice; a hydrophobic breathable film attached to an outer wall of the variable-stiffness sponge pipeline, and configured to isolate the variable-stiffness sponge pipeline from body fluid in the natural orifice; and a gas delivery assembly connected with the variable-stiffness sponge pipeline, and configured to inject high-pressure air or water vapor into a variable-stiffness sponge pipe of the variable-stiffness sponge pipeline; wherein the variable-stiffness sponge pipeline has a stiffness inversely proportional to content of the water vapor.
    Type: Application
    Filed: June 29, 2018
    Publication date: January 7, 2021
    Inventors: Shuxin Wang, Xuyang Ren, Guokai Zhang, Zufeng Shang, Jinhua Li
  • Patent number: 10702253
    Abstract: Disclosed is a natural orifice translumenal minimally invasive surgical apparatus comprising a control box assembly sequentially connected with a hose assembly, a serpentine structure and a tip assembly at a middle position at a distal end of the control box assembly. Axes of the hose assembly and the serpentine structure are coincident with an axis of the tip assembly. The control box assembly is configured to position and replace a minimally invasive surgical instrument, support the surgical tool when being operated, and perform a minimally invasive surgery. The hose assembly is configured to provide passageways for the minimally invasive surgical instrument and a transmission wire and to output motions and loads. The tip assembly is configured to support the minimally invasive surgical instrument when being operated and enable the surgical instrument to have an enlarged motion space range.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: July 7, 2020
    Assignee: TIANJIN UNIVERSITY
    Inventors: Shuxin Wang, Guokai Zhang, Junbo Wei
  • Publication number: 20180280010
    Abstract: Disclosed is a natural orifice translumenal minimally invasive surgical apparatus comprising a control box assembly sequentially connected with a hose assembly, a serpentine structure and a tip assembly at a middle position at a distal end of the control box assembly. Axes of the hose assembly and the serpentine structure are coincident with an axis of the tip assembly. The control box assembly is configured to position and replace a minimally invasive surgical instrument, support the surgical tool when being operated, and perform a minimally invasive surgery. The hose assembly is configured to provide passageways for the minimally invasive surgical instrument and a transmission wire and to output motions and loads. The tip assembly is configured to support the minimally invasive surgical instrument when being operated and enable the surgical instrument to have an enlarged motion space range.
    Type: Application
    Filed: June 9, 2017
    Publication date: October 4, 2018
    Inventors: Shuxin WANG, Guokai ZHANG, Junbo WEI