Patents by Inventor Guoliang Qing

Guoliang Qing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cold shock inducible expression and production of heterologous polypeptides
    Patent number: 7605000
    Abstract: The present invention relates to a DNA molecule or vector and a host cell containing this DNA molecule or vector which can be used to produce a heterologous polypeptide under conditions that elicit a cold shock response in the host cell. The DNA molecule and vector include a nucleotide sequence encoding a heterologous polypeptide and a promoter and 5?-UTR from a cold shock inducible gene which directs its expression. In addition, an AT-rich sequence that enhances translation under cold shock inducible conditions is either present in the coding sequence of the heterologous polypeptide or in an additional element inserted between the coding sequence and the cold shock inducible promoter and 5?-UTR.
    Type: Grant
    Filed: February 25, 2003
    Date of Patent: October 20, 2009
    Assignee: Takara Bio, Inc.
    Inventors: Masayori Inouye, Sangita Phadtare, Bing Xia, Guoliang Qing, Haiping Ke
  • Cold shock inducible expression and production of heterologous polypeptides
    Publication number: 20050272924
    Abstract: The present invention relates to a DNA molecule or vector and a host cell containing the DNA molecule or vector which can be used to produce a heterologous polypeptide under conditions that elicit a cold shock response in the host cell. The DNA molecule and vector include a nucleotide sequence encoding a heterologous polypeptide and a promoter and 5?-UTR from a cold shock inducible gene which directs its expression. IN addition, an AT-rich sequence that enhances translation under cold shock inducible conditions is either present in the coding sequence of the heterologous polypeptide or in an additional element inserted between the coding sequence and the cold shock inducible promoter and 5?-UTR.
    Type: Application
    Filed: February 25, 2003
    Publication date: December 8, 2005
    Inventors: Masayori Inouye, Sangita Phadtare, Bing Xia, Guoliang Qing, Haiping Ke