Patents by Inventor Guolin Zhou

Guolin Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12365926
    Abstract: The invention provides a Saccharomyces cerevisiae strain for producing a human milk lipid substitute. By integrating a heterologous lysophosphatidic acid acyltransferase into Saccharomyces cerevisiae and knocking out its own natural lysophosphatidic acid acyltransferase, the content of palmitic acid (C16:0) at Sn-2 position of triacylglycerol produced by Saccharomyces cerevisiae is increased, to synthesize a human milk lipid substitute. On this basis, a metabolic pathway related gene is knocked out, to further increase the content of human milk lipid substitute in the product. In the present invention, a human milk lipid substitute is de novo synthesized by Saccharomyces cerevisiae for the first time, in which the total fatty acid is 15% or more, and the relative content of C16:0 at Sn-2 position reaches about 60%.
    Type: Grant
    Filed: November 1, 2023
    Date of Patent: July 22, 2025
    Assignees: JIANGNAN UNIVERSITY, INNER MONGOLIA MENGNIU DAIRY (GROUP) COMPANY LIMITED
    Inventors: Long Liu, Jian Chen, Xueqin Lv, Wenyang Wu, Guocheng Du, Jianghua Li, Guolin Zhou, Yanfeng Liu, Chenyang Zhang
  • Publication number: 20240067996
    Abstract: The invention provides a Saccharomyces cerevisiae strain for producing a human milk lipid substitute. By integrating a heterologous lysophosphatidic acid acyltransferase into Saccharomyces cerevisiae and knocking out its own natural lysophosphatidic acid acyltransferase, the content of palmitic acid (C16:0) at Sn-2 position of triacylglycerol produced by Saccharomyces cerevisiae is increased, to synthesize a human milk lipid substitute. On this basis, a metabolic pathway related gene is knocked out, to further increase the content of human milk lipid substitute in the product. In the present invention, a human milk lipid substitute is de novo synthesized by Saccharomyces cerevisiae for the first time, in which the total fatty acid is 15% or more, and the relative content of C16:0 at Sn-2 position reaches about 60%.
    Type: Application
    Filed: November 1, 2023
    Publication date: February 29, 2024
    Inventors: Long LIU, Jian Chen, Xueqin LV, Wenyang Wu, Guocheng Du, Jianghua Li, Guolin Zhou, Yanfeng Liu, Chenyang Zhang
  • Patent number: 10325574
    Abstract: The present disclosure provides a simultaneous display method, system, and computer numerical control machine tool based on QT embedded. The method includes triggering a target QT paint event which displays a first display content; executing a drawing function corresponding to the QT paint event, and meanwhile, triggering a predefined first triggering event; wherein, the first triggering event is used to trigger a frame buffer operation to display a second display content, and the second display content and the first display content are contents required to be simultaneously displayed; displaying the first display content and the second display content simultaneously by a display device. The present disclosure can guarantee that the frame buffer operation is executed after executing the target QT paint event, to ensure that the frame buffer operation and QT embedded drawing are displayed simultaneously, avoiding displaying errors and improving the user experience.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: June 18, 2019
    Assignee: SHENZHEN A&E INTELLIGENT TECHNOLOGY INSTITUTE CO., LTD.
    Inventor: Guolin Zhou
  • Publication number: 20180040308
    Abstract: The present disclosure provides a simultaneous display method, system, and computer numerical control machine tool based on QT embedded. The method includes triggering a target QT paint event which displays a first display content; executing a drawing function corresponding to the QT paint event, and meanwhile, triggering a predefined first triggering event; wherein, the first triggering event is used to trigger a frame buffer operation to display a second display content, and the second display content and the first display content are contents required to be simultaneously displayed; displaying the first display content and the second display content simultaneously by a display device. The present disclosure can guarantee that the frame buffer operation is executed after executing the target QT paint event, to ensure that the frame buffer operation and QT embedded drawing are displayed simultaneously, avoiding displaying errors and improving the user experience.
    Type: Application
    Filed: September 24, 2015
    Publication date: February 8, 2018
    Inventor: Guolin ZHOU
  • Publication number: 20170356682
    Abstract: An evaporator for environmental test chamber includes a plate-type fin and plurality of pipelines wherein: the pipelines are divided into three types: refrigerating pipelines, dehumidifying pipelines and defrosting pipelines; the refrigerating pipelines are arranged alternately one by one, more by more, and one by more with the dehumidifying pipelines in transverse direction of a plate surface of the plate-type fin; refrigerating pipelines receive a refrigerating refrigerant supplied from a refrigerating-system, the dehumidifying pipelines receive dehumidifying refrigerant supplied from a dehumidifying-system, and defrosting pipelines receive hot air discharged from the dehumidifying-system compressor exhaust hole.
    Type: Application
    Filed: March 23, 2015
    Publication date: December 14, 2017
    Applicant: SUZHOU SUSHI TESTING INSTRUMENT CO., LTD.
    Inventors: Xiaoguang HUANG, Ronghua ZHU, Guolin ZHOU
  • Publication number: 20030165949
    Abstract: The invention provides materials and methods for the analysis of gene expression in hematopoietic cells, such as hematopoietic stem/precursor cells of mammals. Materials of the invention include microarrays of polynucleotides collectively characterizing gene expression in hematopoietic cells, as well as a vector comprising at least one such polynucleotide and a host cell containing such a vector. Methods of the invention include diagnostic methods for identifying or detecting expression products collectively characteristic of normal, or abnormal, hematopoietic cells. Other methods of the invention include therapeutic methods for the treatment or prevention of an abnormality such as a disease or condition of a hematopoietic cell, comprising delivery of an effective amount of a suitable material, such as a pharmaceutical composition of the invention, to a cell or patient in need thereof.
    Type: Application
    Filed: December 23, 2002
    Publication date: September 4, 2003
    Inventors: San Ming Wang, Sanggyu Lee, Jianjun Chen, Guolin Zhou, Janet D. Rowley