Abstract: Provided are a pavement coating material and a preparation method thereof. The method for preparing a pavement coating material, includes: S1, adding a film-forming aid to a pure acrylic emulsion and mixing, to obtain an organic material; S2, adding a silane coupling agent to a silica sol and mixing, to obtain an inorganic material; S3, adding a part of a dispersant and a nano-catalyst to deionized water and mixing, to obtain a catalyst aqueous solution; and S4, mixing the organic material and the inorganic material by stirring to obtain a mixed base material, adding the catalyst aqueous solution, a hollow microbead, titanium dioxide, and carbon black sequentially to the mixed base material and mixing, to obtain a mixture, and adding a remaining part of the dispersant and a defoamer to the mixture and mixing, to obtain the pavement coating material.

Abstract: Disclosed are a [1,2,4]triazolo[1,5-a]pyridine compound as JAK inhibitor and an application thereof in preparing a drug for treating a disease related to JAK1 or/and TYK2. Specifically, the present invention relates to a compound represented by formula (I), or an isomer or pharmaceutically acceptable salt thereof.

Abstract: The present disclosure provides immunogenic compositions, such as vaccines, including DNA vaccines, and uses thereof, e.g., to suppress or prevent an immune response and/or to treat or prevent an autoimmune disease.

Abstract: Methods for treating or preventing renal disease or inducing passive immunity against renal disease by administering polynucleotides encoding MCP-1 or both MCP-1 and RANTES are provided. Compositions containing polynucleotides encoding MCP-1 or both MCP-1 and RANTES are also provided.