Patents by Inventor Guoqi ZHU

Guoqi ZHU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOFORM-SPECIFIC CALPAIN INHIBITORS, METHODS OF IDENTIFICATION, AND USES THEREOF
    Publication number: 20190030114
    Abstract: Molecules that selectively inhibit or stimulate the activity of isoforms of calpains are presented. Methods for screening and characterizing such molecules are also presented. Specific functions of calpain-1 calpain-2 in long term potentiation (LTP), learning and memory, neurodegeneration and diseases of synaptic dysfunction are characterized using novel calpain inhibitors, substrates and related methods. The compounds, compositions, and methods described herein are expected to be useful, for treating neurodegenerative diseases and other diseases of synaptic function, and for modulating cognition in patients in need thereof.
    Type: Application
    Filed: November 11, 2015
    Publication date: January 31, 2019
    Applicant: WESTERN UNIVERSITY OF HEALTH SCIENCES
    Inventors: Michel BAUDRY, Xiaoning BI, Steve STANDLEY, Lyna LUO, Yubin WANG, Guoqi ZHU, Victor BRIZ