Abstract: The present invention provides a compound or a pharmaceutically acceptable salt, isomer, prodrug, polymorph or solvate thereof, and a preparation method therefor and use thereof. The compound provided in the present invention has comparable or superior activity to Elagolix as a GnRHR antagonist in calcium flux assays and have better pharmacokinetic properties.

Abstract: An illumination device, an LED driver circuit, a bleeder control circuit and a control method are provided. An AC input voltage is transmitted to a bus line after phase-cut processing. The bleeder control circuit includes a timing module configured to receive a bus voltage and at least one threshold voltage and generate a first time signal; a time processing module configured to receive the first time signal and generate a second time signal based on the first time signal in a previous power frequency half-wave cycle; and a control signal generation module configured to receive the second time signal and generate a first control signal for controlling a bleeder circuit. The beneficial effects of the present disclosure include the bleeder circuit being accurately controlled through the detection of the bus voltage and the implementation of the adaptive control method, thereby improving the operational efficiency and stability of the system.

Abstract: A flyback converter, a constant-current control method, and a lighting system are provided. The constant-current control method includes: sampling a loop current in a resonant loop to obtain a first sampling signal; obtaining zero crossing time of an excitation current in the resonant loop; and turning off a first switch tube when the first sampling signal reaches a reference value, and turning off a second switch tube after the zero crossing time of the excitation current in the resonant loop to control an average value of the excitation current to keep constant. The present disclosure can achieve a constant average value of an excitation current in each switching cycle based on a loop current in a resonant loop on the primary side of the converter, thereby realizing constant-current control of an output current of the converter.

Abstract: A buffer circuit for an LED driver circuit, a LED driver circuit, and a control method, the buffer circuit includes a first control switch connected in series in a rectified input loop and a feedback control module connected to the rectified input loop to obtain a loop current in the rectified input loop for generating a first control signal to the first control switch according to the loop current and a reference signal. The first control switch switches between a fully conducting state and a non-fully-conducting state based on the first control signal and restrains the loop current when the first control switch is in the non-fully-conducting state. The buffer circuit enhances the effect of restraining the current change rate and can effectively restrain current spikes in a circuit, resulting in higher safety and reliability.

Abstract: A leakage protection circuit and a dimming drive circuit are provided. A leakage detection circuit is configured to detect whether leakage occurs between two input terminals that receive an external signal. When leakage occurs, leakage protection measures are taken. A pulse generation circuit receives the sampling signal characterizing the voltage between the two input terminals to compare the sampling signal with two thresholds to control a detection path of the leakage detection circuit to be turned on or off according to a comparison result. The leakage detection path is enabled to be turned on twice by setting two pulse signals in a power frequency period, which can consider the leakage detection of the front-edge phase-cutting dimming and rear-edge phase-cutting dimming of the dimming drive circuit and has a wide range of applications.

Abstract: A content transmission method is provided. The method may include: A first device determines that a distance between the first device and a second device is less than a distance threshold. The first device provides a user with a prompt that content transmission can be performed between the first device and the second device. The first device recognizes a gesture operation performed by the user on the first device, and determines transmission content and a transmission direction of the transmission content between the first device and the second device based on the recognized gesture operation. The first device receives the transmission content from the second device or sends the transmission content to the second device based on the determined transmission direction.

Abstract: A control method of a switching circuit, a control circuit of the switching circuit, and the switching circuit are provided. The switching circuit includes an inductor or a transformer. An operational amplification is performed on an output feedback voltage and a first reference voltage of the switching circuit to obtain a compensation voltage. The compensation voltage controls an on-time of a main switch of the switching circuit. When the current of the inductor or the transformer drops to a threshold, after a time, the main switch is switched from off to on, and the output feedback voltage controls the time. When the output feedback voltage is higher than a first threshold voltage, the compensation voltage is pulled down. When the output feedback voltage is lower than a second threshold voltage, the compensation voltage is pulled up.

Abstract: An oral care implement (100) including a head portion (120) that extends from a proximal end (121) to a distal edge (122) along a longitudinal axis (A-A). The head portion (120) may be formed of a cellulosic material such as a wood material or a bamboo material having a longitudinal grain direction. The head portion (120) may include a plurality of tuft holes (130) such that a bristle tuft (151) is anchored to the head portion (120) within each of the tuft holes (130) by an anchor (200). The anchors (200) may extend along an anchor axis that is oblique to the longitudinal axis (A-A). The bristle tufts (151) may include perimeter bristle tufts (153,154) located within perimeter tuft holes (140) that are adjacent to a perimeter (128) or peripheral edge (126,127) of the head portion (120). The perimeter tuft holes (140) may be located at least 1.80 mm from the perimeter (128) of the head portion (120).

Abstract: A content transmission method includes obtaining, by a first terminal device, a first instruction instructing the first terminal device to perform content transmission with a second terminal device sending, by the first terminal device, to the second terminal device, and in response to the first instruction, first information instructing the second terminal device to determine that that the first terminal device transmits content to the second terminal device. Receiving, by the first terminal device, content transmission direction indication information from the second terminal device, determining, by the first terminal device, first content, and sending, by the first terminal device, the first content to the second terminal device to display the first content.

Abstract: A Near-Field Communication (NFC) antenna and an electronic apparatus include a metal structure on a personal computer (PC), an inductor, a capacitor, and an NFC chip. One end of the metal structure on the PC is coupled to one end of the inductor. The other end of the inductor is coupled to one port of the NFC chip and one end of the capacitor. The other end of the metal structure on the PC is coupled to the other port of the NFC chip and the other end of the capacitor.

Abstract: A tundish, wherein a steel passing hole (43) is provided at a lower portion of a gas-curtain weir refractory body (42); an argon duct (46), a gas chamber (45) and a gas-permeable brick (44) are connected to form a gas-curtain generating device, and the gas-curtain generating device is installed at the lower portion of the gas-curtain weir refractory body (42); the gas-permeable brick (44) is provided in association with the position of the steel passing hole (43), and a length of the gas-permeable brick is designed larger than a width of the steel passing hole (43); and a gas-curtain weir plate (4) is provided in a tundish container, the gas-curtain weir refractory body (42) crosses the tundish container horizontally, and divides the tundish container into a first region and a second region.

Abstract: The present invention discloses a respirator for measuring a respiratory rate of a biofilm. The respirator includes a body, a carbon dioxide absorption tube and a perforated partition disposed in an interior of the body. The perforated partition divides the interior of the body into an oxygen mass-transfer stir zone provided with a stirring device and a biofilm reaction zone for placing MBBR fillers. The carbon dioxide absorption tube is provided with an air vent and contains a solution capable of absorbing CO2. The perforated partition has a first hole corresponding to a middle portion and a lower portion of the perforated partition and acting as a liquid-exchange channel, and a second hole corresponding to an upper portion of the perforated partition and acting as a gas-exchange channel, and the oxygen mass-transfer stir zone is communicated with the biofilm reaction zone through the liquid-exchange channel and the gas-exchange channel.

Abstract: A control method of a switching circuit, a control circuit of the switching circuit, and the switching circuit are provided. The switching circuit includes an inductor or a transformer. An operational amplification is performed on an output feedback voltage and a first reference voltage of the switching circuit to obtain a compensation voltage. The compensation voltage controls an on-time of a main switch of the switching circuit. When the current of the inductor or the transformer drops to a threshold, after a time, the main switch is switched from off to on, and the output feedback voltage controls the time. When the output feedback voltage is higher than a first threshold voltage, the compensation voltage is pulled down. When the output feedback voltage is lower than a second threshold voltage, the compensation voltage is pulled up.