Patents by Inventor Guoqiang Wang

Guoqiang Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF
    Publication number: 20180099957
    Abstract: The present invention provides compounds of Formula I, pharmaceutical compositions comprising these compounds and methods of using these compounds to prevent or treat FXR-mediated or TGR5-mediated diseases or conditions.
    Type: Application
    Filed: October 4, 2017
    Publication date: April 12, 2018
    Inventors: Jun Ma, Guoqiang Wang, Bin Wang, Xuechao Xing, Ruichao Shen, Jing He, Yat Sun Or
  • Method and system for reconstructing unmanned aerial vehicle formation communication topology based on minimum cost arborescence
    Patent number: 9929914
    Abstract: The present disclosure provides a method and system for reconstructing UAV formation communication topology based on minimum cost arborescence, the method comprising: monitoring broadcast communication channel, and judging whether communication failure occurs in UAV in formation; modifying formation communication diagram according to the type of communication failure when communication failure occurs in the UAV; calculating minimum cost arborescence of modified formation communication diagram, and reconstructing UAV formation communication topology according to calculation results.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: March 27, 2018
    Inventors: He Luo, Guoqiang Wang, Xiaoxuan Hu, Huawei Ma, Peng Jin, Wei Xia
  • HYBRID APPROACH WITH CLASSIFICATION FOR NAME RESOLUTION AND PRODUCER SELECTION IN ICN
    Publication number: 20180062935
    Abstract: The disclosure relates to technology for classifying a node in a network. Content published from one or more content producers in the network is received by the node comprising sufficient storage and processing capability to store and process the content received. It is then determined whether the node can receive additional content that is published for one or more other nodes in the network. A metric is calculated for paths from the node to each of the one or more content producers in the network in response to determining that additional content can be received by the node. The node is classified as a home node in the network in response to determining that the metric for paths of the node is shorter than a metric for paths of each of the one or more other nodes in the network.
    Type: Application
    Filed: August 23, 2017
    Publication date: March 1, 2018
    Applicant: Futurewei Technologies, Inc.
    Inventors: Lijun Dong, Guoqiang Wang
  • NUCLEAR FUEL ROD
    Publication number: 20170372802
    Abstract: A Gland Seal End Plug closure for a nuclear fuel rod cladding composed of silicon carbide or other materials that cannot be welded. The sealant is, preferably, made from one or more forms of pure graphite and the ram, seat and other components of the Gland Seal End Plug are formed from high temperature metallic or ceramic materials.
    Type: Application
    Filed: June 21, 2017
    Publication date: December 28, 2017
    Applicant: Westinghouse Electric Company LLC
    Inventors: WILLIAM A. BYERS, Guoqiang Wang, Kevin A. Harding
  • METHOD AND SYSTEM FOR REOPTIMIZING UNMANNED AERIAL VEHICLE FORMATION COMMUNICATION TOPOLOGY BASED ON MINIMUM COST ARBORESCENCE
    Publication number: 20170347285
    Abstract: A method and a system for reoptimizing unmanned aerial vehicle formation communication topology based on minimum cost arborescence are used for optimizing reconstructed UAV formation communication topology after a communication failure occurs on the UAVs in the formation. The method includes calculating a first communication cost of the reconstructed UAV formation communication topology; comparing the first communication cost with a target communication cost for the minimum cost arborescence of the formation communication diagram under a predetermined state; when the first communication cost is greater than the target communication cost for the minimum cost arborescence of the formation communication diagram under the predetermined state, optimizing the reconstructed UAV formation communication topology through a predetermined strategy.
    Type: Application
    Filed: May 30, 2017
    Publication date: November 30, 2017
    Inventors: He LUO, Guoqiang WANG, Xiaoxuan HU, Huawei MA, Peng JIN, Wei XIA
  • Method and System for Reconstructing Unmanned Aerial Vehicle Formation Communication Topology Based on Minimum Cost Arborescence
    Publication number: 20170346679
    Abstract: The present disclosure provides a method and system for reconstructing UAV formation communication topology based on minimum cost arborescence, the method comprising: monitoring broadcast communication channel, and judging whether communication failure occurs in UAV in formation; modifying formation communication diagram according to the type of communication failure when communication failure occurs in the UAV; calculating minimum cost arborescence of modified formation communication diagram, and reconstructing UAV formation communication topology according to calculation results.
    Type: Application
    Filed: March 16, 2017
    Publication date: November 30, 2017
    Applicant: Hefei University of Technology
    Inventors: He Luo, Guoqiang Wang, Xiaoxuan Hu, Huawei MA, Peng Jin, Wei Xia
  • Isoxazole Derivatives as FXR Agonists and Methods of Use Thereof
    Publication number: 20170334894
    Abstract: The present invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.
    Type: Application
    Filed: May 17, 2017
    Publication date: November 23, 2017
    Inventors: Yat Sun Or, Yong He, Ruichao Shen, Xuechao Xing, Brett Granger, Bin Wang, Jun Ma, Jing He, Jiang Long, Guoqiang Wang
  • DECENTRALIZED, HIERARCHICAL, AND OVERLAY-DRIVEN MOBILITY SUPPORT ARCHITECTURE FOR INFORMATION-CENTRIC NETWORKS
    Publication number: 20170339228
    Abstract: An anchor server in an information-centric network (ICN) receives registration and deregistration requests from one or more producers in the ICN. In response to a producer initially registering, the anchor server stores records associating the producer with content available from the producer via a first point of attachment. In response to the producer deregistering, the records are marked as deactivated. While the records are deactivated, requests for the content from consumers may be queued. In response to the producer reregistering as being connected to the ICN via a second point of attachment, the queued requests are forwarded to the producer via the second point of attachment.
    Type: Application
    Filed: May 19, 2016
    Publication date: November 23, 2017
    Inventors: Aytac Azgin, Ravishankar Ravindran, Guoqiang Wang
  • Isoxazole Analogs as FXR Agonists and Methods of Use Thereof
    Publication number: 20170334893
    Abstract: The present invention provides compounds of Formula I: pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.
    Type: Application
    Filed: May 17, 2017
    Publication date: November 23, 2017
    Inventors: Yat Sun Or, Jun Ma, Bin Wang, Yong He, Xuechao Xing, Ruichao Shen, Brett Granger, Jing He, Jiang Long, Guoqiang Wang
  • Isoxazole Derivatives as FXR Agonists and Methods of Use Thereof
    Publication number: 20170333399
    Abstract: The present invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated by FXR. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR and methods for their preparation and use.
    Type: Application
    Filed: May 17, 2017
    Publication date: November 23, 2017
    Inventors: Yat Sun Or, Xuechao Xing, Ruichao Shen, Bin Wang, Brett Granger, Jun Ma, Jing He, Jiang Long, Yong He, Guoqiang Wang
  • ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF
    Publication number: 20170304272
    Abstract: The present invention provides compounds of Formula I, pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.
    Type: Application
    Filed: April 26, 2017
    Publication date: October 26, 2017
    Inventors: Yat Sun Or, Bin Wang, Xuechao Xing, Ruichao Shen, Brett Granger, Jun Ma, Jing He, Yong He, Jiang Long, Guoqiang Wang
  • ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF
    Publication number: 20170304270
    Abstract: The present invention provides compounds of Formula I: pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.
    Type: Application
    Filed: April 26, 2017
    Publication date: October 26, 2017
    Inventors: Yat Sun Or, Brett Granger, Ruichao Shen, Xuechao Xing, Bin Wang, Jun Ma, Jing He, Jiang Long, Yong He, Guoqiang Wang
  • ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF
    Publication number: 20170304271
    Abstract: The present invention provides compounds of Formula I, pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.
    Type: Application
    Filed: April 26, 2017
    Publication date: October 26, 2017
    Inventors: Yat Sun Or, Ruichao Shen, Xuechao Xing, Brett Granger, Bin Wang, Jun Ma, Jing He, Yong He, Jiang Long, Guoqiang Wang
  • Certificateless data verification with revocable signatures
    Patent number: 9774610
    Abstract: A method comprises accessing, by a processor of a machine, an encrypted data packet from a first source, the encrypted data packet being accompanied by a signature of the first source. The processor further accesses parameters from a second source and verifies, based on the signature of the first source and the parameters, that the encrypted data packet was generated by the first source. The method further comprises decrypting, based on the verification that the encrypted data packet was generated by the first source, by the processor, the encrypted data packet.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: September 26, 2017
    Assignee: Futurewei Technologies, Inc.
    Inventors: Qingji Zheng, Guoqiang Wang
  • Benzoic Acid Derivatives of Bile Acid as FXR/TGR5 Agonists and Methods of Use Thereof
    Publication number: 20170240586
    Abstract: The present invention provides compounds of Formula I: pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated by FXR and/or TGR5.
    Type: Application
    Filed: February 22, 2017
    Publication date: August 24, 2017
    Inventors: Yat Sun Or, Xuechao Xing, Guoqiang Wang, Ruichao Shen, Jing He
  • HETEROARYL CONTAINING BILE ACID ANALOGS AS FXR/TGR5 AGONISTS AND METHODS OF USE THEREOF
    Publication number: 20170240587
    Abstract: The present invention provides compounds of Formula I, pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated by FXR and/or TGR5.
    Type: Application
    Filed: February 22, 2017
    Publication date: August 24, 2017
    Inventors: Yat Sun Or, Jing He, Guoqiang Wang, Xuechao Xing
  • DEUTERATED BILE ACID DERIVATIVES AS FXR/TGR5 AGONISTS AND METHODS OF USE THEREOF
    Publication number: 20170240585
    Abstract: The present invention provides compounds of Formula (I) or Formula (II): pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated by FXR and/or TGR5.
    Type: Application
    Filed: February 22, 2017
    Publication date: August 24, 2017
    Inventors: Guoqiang Wang, Yat Sun Or, Jiang Long, Guoyou Xu, Peng Dai, Ruichao Shen, Xuechao Xing, Jing He
  • Deuterated nucleoside/tide derivatives
    Patent number: 9718851
    Abstract: The present invention provides nucleoside phosphoramidate compounds of Formula I, where R1, R2a, R2b, R4, R5a, R5b, Rb5, Rb6 and D are as defined herein. The invention further includes pharmaceutical compositions comprising a compound of Formula I, methods of use of these compounds for treating a viral infection, and methods of producing these compounds.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: August 1, 2017
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Jay R. Luly, Bin Wang, Guoqiang Wang, Yat Sun Or
  • Cyclosporin analogues for preventing or treating hepatitis C infection
    Patent number: 9669095
    Abstract: The present invention relates to novel cyclosporine analogs having antiviral activity against HCV and useful in the treatment of HCV infections. More particularly, the invention relates to novel cyclosporine analog compounds, compositions containing such compounds and methods for using the same, as well as processes for making such compounds.
    Type: Grant
    Filed: November 3, 2015
    Date of Patent: June 6, 2017
    Assignee: ENANTA PHARMACEUTICALS, INC.
    Inventors: Guoqiang Wang, In Jong Kim, Yat Sun Or
  • Cyclosporin analogues for preventing or treating hepatitis C infection
    Patent number: 9616099
    Abstract: The present invention relates to novel cyclosporine analogs having antiviral activity against HCV and useful in the treatment of HCV infections. More particularly, the invention relates to novel cyclosporine analog compounds, compositions containing such compounds and methods for using the same, as well as processes for making such compounds.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: April 11, 2017
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Yat Sun Or, Guoqiang Wang, Jiang Long, In Jong Kim