Patents by Inventor Guoqing Zhou

Guoqing Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250240909
    Abstract: A double-air-duct laser radar heat dissipation structure includes a radar box body, a first and a second heat dissipation portion. The first heat dissipation portion for heat dissipation of a high-speed acquisition module comprises two air duct structures and an air duct switching mechanism. When an unmanned aerial vehicle works, a first air duct improves heat dissipation of a radar system through an air flow generated by the unmanned aerial vehicle; after landing, the air duct switching mechanism disconnects the first air duct and connects a second air duct to a heat dissipation system to meet heat dissipation of a laser radar in a data processing stage. The second heat dissipation portion completes heat dissipation of a laser device through TEC refrigeration and a heat sink. The present disclosure reduces energy consumption and makes the radar adapt to various working conditions while improving the heat dissipation.
    Type: Application
    Filed: December 27, 2024
    Publication date: July 24, 2025
    Applicant: GUILIN UNIVERSITY OF TECHNOLOGY
    Inventors: Guoqing ZHOU, Angte CAI
  • Publication number: 20250237751
    Abstract: The present disclosure discloses a self-adaptive trigger acquisition method of an airborne bathymetric survey laser radar, including calculating a distance between laser light and a water surface and a height between the laser radar and the water surface, and obtaining delay time before sampling; converting water surface and water bottom echo numerical values into corresponding voltage amplitude values, then calculating corresponding electric signals, and calculating light energy by a photoelectric conversion relation; determining a water body attenuation coefficient by water surface and water bottom light energy losses; and determining a maximum water depth by the solved water body attenuation coefficient, then solving sampling time, and finally realizing self-adaptive trigger acquisition.
    Type: Application
    Filed: December 19, 2024
    Publication date: July 24, 2025
    Applicant: GUILIN UNIVERSITY OF TECHNOLOGY
    Inventors: Guoqing ZHOU, Kaiyun BAO, Xiang ZHOU
  • Publication number: 20250152644
    Abstract: Provided are a recombinant oncolytic virus and a use thereof. The recombinant oncolytic virus includes an M protein and an antigen encoded by an exogenous gene, wherein the M protein includes the following site mutations compared to an amino acid sequence as shown in SEQ ID NO 1: mutating of methionine at position 51 into arginine (M51R); mutating of valine at position 221 into phenylalanine (V221F); and mutating of serine at position 226 into arginine (S226R). The recombinant oncolytic viruses provided have better infective ability and killing ability in vitro to abnormally proliferative (tumor) LLC cell and are all not easy to eliminate in the LLC cell, greatly reducing the infective ability of the recombinant oncolytic viruses to normal cells.
    Type: Application
    Filed: January 14, 2025
    Publication date: May 15, 2025
    Inventors: Guoqing ZHOU, Fan ZHANG, Liang MA, Ting TIAN
  • Patent number: 12196885
    Abstract: The present disclosure relates to a stray light suppression device for bathymetric LiDAR onboard unmanned shipborne, belonging to the technical field of LiDAR water depth detection, particularly to a stray light suppression device for bathymetric LiDAR onboard unmanned shipborne. The device comprises an optical system component, a first objective lens barrel, a second objective lens barrel, a spectroscope barrel, a first eyepiece barrel a, a first eyepiece barrel b, a second eyepiece barrel a, a second eyepiece barrel b, a PMT detector a, a PMT detector b and a spectroscope supporting structure. Stray light suppression of an optical system with minimal field-of-view is realized, and stray light propagated by first-order, second-order and third-order scattered light paths is suppressed, so that a water depth detection capability of the bathymetric LiDAR onboard unmanned shipborne is improved and a dynamic detection range is expanded.
    Type: Grant
    Filed: June 21, 2023
    Date of Patent: January 14, 2025
    Assignee: GUILIN UNIVERSITY OF TECHNOLOGY
    Inventors: Guoqing Zhou, Zhexian Liu
  • Publication number: 20240424040
    Abstract: The present application discloses an oncolytic virus and a use thereof. The oncolytic virus comprises an M protein, in which the M protein includes amino acid substitution(s) at one or more of the following positions compared to an amino acid sequence set forth in SEQ ID NO 1: position 32, position 33, position 49, position 54, position 133, and position 225. Further disclosed are an expression vector for the oncolytic virus, a virus production cell capable of producing the oncolytic virus, and a pharmaceutical composition including the oncolytic virus, as well as a method for preparing the oncolytic virus, the expression vector for the oncolytic virus, the virus production cell, and/or the pharmaceutical composition, and a use of the oncolytic virus, the expression vector for the oncolytic virus, the virus production cell, and/or the pharmaceutical composition.
    Type: Application
    Filed: July 26, 2024
    Publication date: December 26, 2024
    Inventors: Guoqing ZHOU, Fan ZHANG, Liang MA, Ting TIAN
  • Publication number: 20240418832
    Abstract: The present disclosure relates to a stray light suppression device for bathymetric LiDAR onboard unmanned shipborne, belonging to the technical field of LiDAR water depth detection, particularly to a stray light suppression device for bathymetric LiDAR onboard unmanned shipborne. The device comprises an optical system component, a first objective lens barrel, a second objective lens barrel, a spectroscope barrel, a first eyepiece barrel a, a first eyepiece barrel b, a second eyepiece barrel a, a second eyepiece barrel b, a PMT detector a, a PMT detector b and a spectroscope supporting structure. Stray light suppression of an optical system with minimal field-of-view is realized, and stray light propagated by first-order, second-order and third-order scattered light paths is suppressed, so that a water depth detection capability of the bathymetric LiDAR onboard unmanned shipborne is improved and a dynamic detection range is expanded.
    Type: Application
    Filed: June 21, 2023
    Publication date: December 19, 2024
    Applicant: GUILIN UNIVERSITY OF TECHNOLOGY
    Inventors: Guoqing ZHOU, Zhexian LIU
  • Patent number: 12146987
    Abstract: An airborne super-continuum 50-band hyperspectral light detection and ranging system comprises an integrated control system, a storage unit, a super-continuum laser system, an optical transmitting system, a reflecting mirror, a scanning system, an optical receiving system, a super-continuum hyperspectral laser detection system, a plane array CCD camera. The operation process includes super-continuum laser system emitting continuous hyperspectral pulsed lasers, performing lasers beam expansion and collimation, emitting it to ground objects, reflecting it, receiving it by the scanning system, transmitting to the optical receiving system, and focusing it into hyperspectral laser detection system for outputting laser hyperspectrum and 3D spatial data, storing laser data in the storage unit with high-resolution multi-spectral data.
    Type: Grant
    Filed: June 11, 2021
    Date of Patent: November 19, 2024
    Assignee: Guilin University of Technology
    Inventors: Guoqing Zhou, Xiang Zhou, Jiasheng Xu
  • Publication number: 20240350318
    Abstract: The present invention falls within the field of articles for daily use, and particularly relates to a sleep noise-proof structure provided on an eye-shrouding member being an eye patch or a sleeping cap and having an eye shield for shrouding the eyes, wherein the sleep noise-proof structure comprises two wires and two earplugs, the wires have a first end and a second end, and the first end is fixedly connected to the front side of the eye shield, and the second end is connected to an earplug. Since the earplug is connected to the front side of the eye shield with a wire, not only the problem of loss of the earplug can be prevented, but also the ear cannot be tightened and the overall comfort can be increased for a better experience.
    Type: Application
    Filed: March 30, 2024
    Publication date: October 24, 2024
    Applicant: Dongguan Pengteng Hardware and Electronics Co. Ltd
    Inventor: Guoqing Zhou
  • Patent number: 12118780
    Abstract: The present disclosure relates to a PointEFF method for urban object classification with LiDAR point cloud data, and belongs to the field of LiDAR point cloud classification. The method comprises: point cloud data segmentation; End-to-end feature extraction layer construction; External feature fusion layer construction; and precision evaluation.
    Type: Grant
    Filed: July 14, 2023
    Date of Patent: October 15, 2024
    Assignee: GUILIN UNIVERSITY OF TECHNOLOGY
    Inventors: Guoqing Zhou, Yue Jiang, Haoyu Wang
  • Publication number: 20240280707
    Abstract: The present invention discloses a POS high-accuracy positioning method under occlusion, comprising: integrating single-point positioning data and differential correction data for solution to acquire high-accuracy position information; implementing a buffer through an RAM of an FPGA to cache the collected position information and a sampling time; when a satellite signal loss is detected by a system, fetching five pieces of position information from the RAM at a time before the signal is lost and five pieces of position information at a time after the signal is reappeared, and filtering the information to obtain filtered data; constructing an equation by using the filtered data, and estimating a signal lost position. By triggering an occlusion algorithm through the FPGA, the present invention improves an ability of a POS system to work in areas with weak satellite signals and meanwhile reduces an operation time, thereby meeting practical needs.
    Type: Application
    Filed: February 6, 2024
    Publication date: August 22, 2024
    Applicant: GUILIN UNIVERSITY OF TECHNOLOGY
    Inventors: Guoqing ZHOU, Jianwu LIU, Jiasheng XU, Ertao GAO, Xinkun YUAN
  • Publication number: 20240226209
    Abstract: Provided is an oncolytic virus, including an M protein and a G protein. The M protein includes amino acid substitutions at positions 51, 221, and 226 compared with an amino acid sequence as shown in SEQ ID NO: 1. The G protein includes at least one amino acid substitution compared with an amino acid sequence as shown in SEQ ID NO: 2. Further provided are an expression vector of the oncolytic virus, a virus production cell for producing the oncolytic virus, and a pharmaceutical composition comprising the oncolytic virus, and a method for preparing the oncolytic virus, the expression vector of the oncolytic virus, the virus production cell, and/or the pharmaceutical composition, and an use thereof.
    Type: Application
    Filed: January 15, 2024
    Publication date: July 11, 2024
    Inventors: Guoqing Zhou, Fan Zhang
  • Publication number: 20240183952
    Abstract: The present disclosure relates to a lightweight and small bathymetry LiDAR multi-channel high sampling rate high-precision real-time synchronous acquisition and storage system, which adopts an ADC+FPGA+ZYNQ architecture to implement four-channel high-rate real-time synchronous parallel sampling, has synchronization error less than 300 ps, sampling rate s as high as 2 GSPS, and sampling precision as high as 14 bits, and comprises an FPGA system acquisition carrier board unit for implementing laser radar echo data acquisition and storage, PMT controlling, data maximum value feedback, peripheral interface design and storage control; a storage daughter board unit for implementing storage of echo data and export of 100 Mbps Ethernet, and an upper computer data conversion software for implementing conversion of original echo data files into decimal or hexadecimal csv files.
    Type: Application
    Filed: December 4, 2023
    Publication date: June 6, 2024
    Applicant: GUILIN UNIVERSITY OF TECHNOLOGY
    Inventors: Guoqing ZHOU, Haotian ZHANG
  • Publication number: 20240020970
    Abstract: The present disclosure relates to a PointEFF method for urban object classification with LiDAR point cloud data, and belongs to the field of LiDAR point cloud classification. The method comprises: point cloud data segmentation; End-to-end feature extraction layer construction; External feature fusion layer construction; and precision evaluation.
    Type: Application
    Filed: July 14, 2023
    Publication date: January 18, 2024
    Applicant: GUILIN UNIVERSITY OF TECHNOLOGY
    Inventors: Guoqing ZHOU, Yue JIANG, Haoyu WANG
  • Publication number: 20230256079
    Abstract: The present application relates to an attenuated oncolytic virus strain, an oncolytic virus vaccine and a drug for treating tumors by combining the oncolytic virus vaccine with immune cells. The present application provides a new attenuated oncolytic virus strain by a site-directed mutation of a matrix protein M of a VSV wild-type virus. On the basis of the attenuated oncolytic virus strain, the present application further provides a vaccine that can be used in tumor treatment. On the basis of the vaccine, the present application further provide a drug that can effectively treat multiple kinds of tumors by combining the vaccine with immune cells.
    Type: Application
    Filed: November 11, 2022
    Publication date: August 17, 2023
    Inventors: Guoqing ZHOU, He YANG, Fan ZHANG, Suhong ZHANG
  • Publication number: 20230190838
    Abstract: The present application relates to a medicine for treating tumors. A novel attenuated oncolytic virus strain is provided by means of a site-directed mutation of a wild-type virus matrix protein M of a vesicular stomatitis virus. On the basis of the attenuated oncolytic virus strain, an oncolytic virus vaccine is provided by inserting an exogenous gene into the attenuated strain. A medicine capable of treating multiple types of tumors is provided by the use of the oncolytic virus vaccine in combination with the immune checkpoint inhibitor.
    Type: Application
    Filed: November 11, 2022
    Publication date: June 22, 2023
    Inventors: Guoqing Zhou, He Yang, Fan Zhang, Suhong Zhang
  • Patent number: 11569275
    Abstract: The present disclosure provides an array substrate, a method for preparing the same, and a display device. The method includes: forming a metal layer on a base substrate; coating a photoresist on the metal layer; exposing the photoresist by a mask plate in such a manner that an amount of light acting on a first photoresist portion is less than that of light acting on a second photoresist portion to form a first photoresist reserved portion located and a second photoresist reserved portion located; after etching off the metal portion, stripping the first photoresist reserved portion and the second photoresist reserved portion, to obtain the first metal pattern located in the fan-out area and the second metal pattern located in the display area, in which a period size of the first metal pattern being smaller than a period size of the second metal pattern.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: January 31, 2023
    Assignees: ORDOS YUANSHENG OPTOELECTRONICS CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Guoqing Zhou, Chao Wang, Shengwei Zhao, Jingping Lv, Lin Xie, Zhiqiang Chang
  • Patent number: 11411072
    Abstract: Disclosed are a display substrate, a display device, a manufacturing method and a repairing method. A capacitor structure in the display substrate includes a first electrode and a second electrode. The first electrode includes a first main body portion extending in a first direction, first branch portions extending in a second direction, and a first connection portion connecting the first branch portions to the first main body portion. The second electrode includes a second main body portion extending in the first direction, second branch portions extending in the second direction, and a second connection portion connecting the second branch portions to the second main body portion. One side of the first electrode having the first branch portions faces one side of the second electrode having the second branch portions, and each first branch portion and a corresponding second branch portion form a capacitor.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: August 9, 2022
    Assignees: ORDOS YUANSHENG OPTOELECTRONICS CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Huafeng Liu, Shengwei Zhao, Chaochao Sun, Chao Wang, Jingping Lv, Lin Xie, Guoqing Zhou, Panpan Zhang, Tengfei Wang, Hsinghua Pan, Lele Li, Zhiqiang Chang, Shaocong Dang, Shijie Mu, Zhen Wang
  • Publication number: 20210396853
    Abstract: An airborne super-continuum 50-band hyperspectral light detection and ranging system comprises an integrated control system, a storage unit, a super-continuum laser system, an optical transmitting system, a reflecting mirror, a scanning system, an optical receiving system, a super-continuum hyperspectral laser detection system, a plane array CCD camera. The operation process includes super-continuum laser system emitting continuous hyperspectral pulsed lasers, performing lasers beam expansion and collimation, emitting it to ground objects, reflecting it, receiving it by the scanning system, transmitting to the optical receiving system, and focusing it into hyperspectral laser detection system for outputting laser hyperspectrum and 3D spatial data, storing laser data in the storage unit with high-resolution multi-spectral data.
    Type: Application
    Filed: June 11, 2021
    Publication date: December 23, 2021
    Inventors: Guoqing ZHOU, Xiang ZHOU, Jiasheng XU
  • Patent number: D1052534
    Type: Grant
    Filed: November 17, 2023
    Date of Patent: November 26, 2024
    Assignee: Dongguan Pengteng Hardware Electronic Co., Ltd.
    Inventor: Guoqing Zhou
  • Patent number: D1074610
    Type: Grant
    Filed: May 17, 2024
    Date of Patent: May 13, 2025
    Assignee: Dongguan Pengteng Hardware Electronic Co., Ltd.
    Inventor: Guoqing Zhou