Patents by Inventor Guoquan Wang

Guoquan Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 8-heteroaryl xanthines
    Patent number: 7732455
    Abstract: Selective antagonists of A2B adenosine receptors like those of formula I are provided. These compounds and compositions are useful as pharmaceutical agents.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: June 8, 2010
    Assignee: PGx Health, LLC
    Inventors: Guoquan Wang, Jayson M. Rieger, Robert D. Thompson
  • PYRAZOLYL SUBSTITUTED XANTHINES
    Publication number: 20100120765
    Abstract: The present invention provides compounds and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Application
    Filed: July 22, 2009
    Publication date: May 13, 2010
    Applicant: PGXHEALTH, LLC
    Inventors: Guoquan Wang, Jayson M. Rieger, Robert D. Thompson
  • METHODS FOR THE SYNTHESIS OF UNSYMMETRICAL CYCLOALKYL SUBSTITUTED XANTHINES
    Publication number: 20100004445
    Abstract: The present invention provides compounds and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents. Also provided are processes for the preparation of the compounds and their intermediates.
    Type: Application
    Filed: July 15, 2009
    Publication date: January 7, 2010
    Applicant: PGxHealth, LLC
    Inventors: Guoquan Wang, Jayson M. Rieger, Robert Thompson
  • Pyrazolyl substituted xanthines
    Patent number: 7618962
    Abstract: The present invention provides compounds and pharmaceutical compositions that are substituted pyridyl-linked-xanthines of formula I which are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Grant
    Filed: February 27, 2006
    Date of Patent: November 17, 2009
    Assignee: PGX Health, LLC
    Inventors: Guoquan Wang, Jayson M. Rieger, Robert D. Thompson
  • Pyridyl substituted xanthines
    Patent number: 7601723
    Abstract: The present invention provides compounds and pharmaceutical compositions that are substituted pyridyl-linked-xanthines of formula I which are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Grant
    Filed: February 27, 2006
    Date of Patent: October 13, 2009
    Assignee: PGx Health, LLC
    Inventors: Guoquan Wang, Jayson M. Rieger, Robert D. Thompson
  • Methods for the synthesis of unsymmetrical cycloalkyl substituted xanthines
    Patent number: 7598379
    Abstract: The present invention provides processes for making pyridyl-linked-xanthines of formula VII, from 5,6-diamino-1H-pyrimidine-2,4-diones of formula II and acylating agents of formula VI. The xanthines are expected to be are selective antagonists of A2B adenosine receptors (ARs).
    Type: Grant
    Filed: February 27, 2006
    Date of Patent: October 6, 2009
    Assignee: PGx Health, LLC
    Inventors: Guoquan Wang, Jayson M. Rieger, Robert D. Thompson
  • Derivatives of 8-substituted xanthines
    Patent number: 7579348
    Abstract: The present invention provides compounds and pharmaceutical compositions that are substituted pyridyl-linked-xantbines of formula I which are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Grant
    Filed: February 27, 2006
    Date of Patent: August 25, 2009
    Assignee: PGxHealth, LLC
    Inventors: Guoquan Wang, Jayson M. Rieger, Robert D. Thompson
  • SUBSTITUTED 8-[6-AMINO-3PYRIDYL]XANTHINES
    Publication number: 20090163491
    Abstract: The present invention provides substituted 8-[6-amino-3-pyridyl]xanthines and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Application
    Filed: December 17, 2008
    Publication date: June 25, 2009
    Inventors: Robert D. Thompson, Guoquan Wang, Anthony Beauglehole, Frank Schmidtmann
  • PYRROLO[3,2-D]PYRIMIDINES THAT ARE SELECTIVE ANTAGONISTS OF A2B ADENOSINE RECEPTORS
    Publication number: 20090082347
    Abstract: The present invention provides compounds of the following formula and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Application
    Filed: November 6, 2008
    Publication date: March 26, 2009
    Inventors: Guoquan Wang, Robert D. Thompson
  • Pyrrolo[3,2-D] pyrimidines that are selective antagonists of Aadenosine receptors
    Patent number: 7470697
    Abstract: The present invention provides compounds of the following formula and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: December 30, 2008
    Assignee: Adenosine Therapeutics, LLC
    Inventors: Guoquan Wang, Robert D. Thompson
  • Substituted 8-Heteroaryl Xanthines
    Publication number: 20080200456
    Abstract: The present invention provides compounds and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Application
    Filed: December 14, 2007
    Publication date: August 21, 2008
    Inventors: Guoquan Wang, Jayson M. Rieger, Robert D. Thompson
  • Antagonists of A2B adenosine receptors for treatment of inflammatory bowel disease
    Publication number: 20080176845
    Abstract: The present invention relates to method for treating inflammatory bowel disease that includes administration of an effective amount of an antagonist of A2B adenosine receptors (ARs).
    Type: Application
    Filed: November 5, 2007
    Publication date: July 24, 2008
    Inventors: Shanthi V. Sitaraman, Joel M. Linden, Guoquan Wang, Robert Douglas Thompson, Jayson M. Rieger
  • Pyrrolo[3,2-D] pyrimidines that are selective antagonists of A2badenosine receptors
    Publication number: 20080125425
    Abstract: The present invention provides compounds of the following formula and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Application
    Filed: August 31, 2007
    Publication date: May 29, 2008
    Inventors: Guoquan Wang, Robert D. Thompson
  • Substituted 8-heteroaryl xanthines
    Patent number: 7342006
    Abstract: Selective antagonists of A2B adenosine receptors like those of formula I are provide. The compounds and compositions are useful as pharmaceutical agents.
    Type: Grant
    Filed: August 20, 2004
    Date of Patent: March 11, 2008
    Assignee: Adenosine Therapeutics, LLC
    Inventors: Guoquan Wang, Jayson M. Rieger, Robert D. Thompson
  • Substituted 8-[6-amino-3-pyridyl]xanthines
    Publication number: 20080004292
    Abstract: The present invention provides substituted 8-[6-amino-3-pyridyl]xanthines and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Application
    Filed: June 12, 2007
    Publication date: January 3, 2008
    Inventors: Guoquan Wang, Robert Thompson, Jayson Rieger
  • Derivatives of 8-substituted xanthines
    Publication number: 20070249598
    Abstract: The present invention provides compounds and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Application
    Filed: February 27, 2006
    Publication date: October 25, 2007
    Inventors: Guoquan Wang, Jayson Rieger, Robert Thompson
  • Methods for the synthesis of unsymmetrical cycloalkyl substituted xanthines
    Publication number: 20070105821
    Abstract: The present invention provides compounds and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents. Also provided are processes for the preparation of the compounds and their intermediates.
    Type: Application
    Filed: February 27, 2006
    Publication date: May 10, 2007
    Inventors: Guoquan Wang, Jayson Rieger, Robert Thompson
  • Pyridyl substituted xanthines
    Publication number: 20070072843
    Abstract: The present invention provides compounds and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Application
    Filed: February 27, 2006
    Publication date: March 29, 2007
    Inventors: Guoquan Wang, Jayson Rieger, Robert Thompson
  • Pyrazolyl substituted xanthines
    Publication number: 20070066631
    Abstract: The present invention provides compounds and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Application
    Filed: February 27, 2006
    Publication date: March 22, 2007
    Inventors: Guoquan Wang, Jayson Rieger, Robert Thompson
  • Substituted 8-heteroaryl xanthines
    Publication number: 20050065341
    Abstract: The present invention provides compounds and pharmaceutical compositions that are selective antagonists of A2B adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
    Type: Application
    Filed: August 20, 2004
    Publication date: March 24, 2005
    Inventors: Guoquan Wang, Jayson Rieger, Robert Thompson