Patents by Inventor Guorui MI

Guorui MI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,7-naphthyridine derivative and preparation method and use therefor
    Patent number: 11981669
    Abstract: A compound represented by formula (I) or a tautomer, an optical isomer, a nitrogen oxide, a solvate, a pharmaceutically acceptable salt or prodrug thereof are useful for treating or relieving an HIF-related and/or EPO-related disease or condition in patient. The preparation method for the compound, and use of a drug composition containing the compound and the compound or the drug composition in preparation of a drug are also provided.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: May 14, 2024
    Assignee: CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD
    Inventors: Yan Zhang, Miaomiao Wei, Xuejiao Zhang, Guorui Mi, Hui An, Bing Wei, Qian Guo
  • FUSED AZA-HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF
    Publication number: 20230227460
    Abstract: A compound of formula (I) or a tautomer, a stereoisomer, a solvate, a nitrogen oxide, a prodrug, an isotope derivative or a pharmaceutically acceptable salt thereof exhibit kinase inhibitory activity against a variety of kinases (such as TRK, ALK and ROS1) and mutants thereof, in particular TRK and a mutant form thereof. An in vitro cell inhibitory activity test and an in vivo anti-tumor model test show that the compounds have a strong inhibitory effect on a variety of cells containing TRK mutations and tumors, have a good safety, and have a good clinical value as drugs.
    Type: Application
    Filed: May 14, 2021
    Publication date: July 20, 2023
    Inventors: Guorui MI, Yan ZHANG, Chunhua JIANG, Yanxia XU, Lixue FAN, Xuejiao ZHANG, Yanan QIN
  • 1,7-NAPHTHYRIDINE DERIVATIVE AND PREPARATION METHOD AND USE THEREFOR
    Publication number: 20210332043
    Abstract: A compound represented by formula (I) or a tautomer, an optical isomer, a nitrogen oxide, a solvate, a pharmaceutically acceptable salt or prodrug thereof are useful for treating or relieving an HIF-related and/or EPO-related disease or condition in patient. The preparation method for the compound, and use of a drug composition containing the compound and the compound or the drug composition in preparation of a drug are also provided.
    Type: Application
    Filed: August 29, 2019
    Publication date: October 28, 2021
    Inventors: Yan ZHANG, Miaomiao WEI, Xuejiao ZHANG, Guorui MI, Hui AN, Bing WEI, Qian GUO
  • Quinazoline derivative
    Patent number: 10774079
    Abstract: Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: September 15, 2020
    Assignee: CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.
    Inventors: Ying Shi, Qingzhi Gao, Xiaozhuo Chen, Yi Mi, Yaran Zhang, Hanyu Yang, Yujie Chen, Chunlei Liu, Guorui Mi, Yuxiu Ma, Dongmin Shen, Yang Guo, Linjing Fan
  • QUINAZOLINE DERIVATIVE
    Publication number: 20190367500
    Abstract: Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug.
    Type: Application
    Filed: August 8, 2019
    Publication date: December 5, 2019
    Inventors: Ying SHI, Qingzhi GAO, Xiaozhuo CHEN, Yi MI, Yaran ZHANG, Hanyu YANG, Yujie CHEN, Chunlei LIU, Guorui MI, Yuxiu MA, Dongmin SHEN, Yang GUO, Linjing FAN
  • Quinazoline derivative
    Patent number: 10421754
    Abstract: Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: September 24, 2019
    Assignee: CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.
    Inventors: Ying Shi, Qingzhi Gao, Xiaozhuo Chen, Yi Mi, Yaran Zhang, Hanyu Yang, Yujie Chen, Chunlei Liu, Guorui Mi, Yuxiu Ma, Dongmin Shen, Yang Guo, Linjing Fan
  • QUINAZOLINE DERIVATIVE
    Publication number: 20170226099
    Abstract: Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug.
    Type: Application
    Filed: August 11, 2015
    Publication date: August 10, 2017
    Inventors: Ying SHI, Qingzhi GAO, Xiaozhuo CHEN, Yi MI, Yaran ZHANG, Hanyu YANG, Yujie CHEN, Chunlei LIU, Guorui MI, Yuxiu MA, Dongmin SHEN, Yang GUO, Linjing FAN