Patents by Inventor Guoshi LIU

Guoshi LIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11931337
    Abstract: Provided are an antioxidant complex for reducing the number of somatic cells in a livestock animal and a preparation method and application thereof. Active components of the preparation are melatonin (MT) having a centration of 2-30 g/L and vitamin C having a concentration of 1-14.3 g/L. The antioxidant complex provided in the present invention can effectively reduce the number of somatic cells in a diary cow and improve milk quality.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: March 19, 2024
    Assignee: CHINA AGRICULTURAL UNIVERSITY
    Inventor: Guoshi Liu
  • Patent number: 11896580
    Abstract: The disclosure discloses a composition containing melatonin as an effective ingredient, and its application in improving DHI production performance and improving milk quality. The composition containing melatonin as an effective ingredient according to the present disclosure can significantly reduce the somatic cell count in milk and improve milk quality. Under the conditions of different seasons, ages, and lactation periods, the administration of the composition containing melatonin as an active ingredient according to the present disclosure can significantly reduce the somatic cell score of cow milk (p<0.01), increase the protein content and lactose content in milk, and meanwhile reduce the fat content and urea nitrogen content in milk. In summary, the composition containing melatonin as an effective ingredient according to the present disclosure can improve the quality of milk and increase the efficiency of dairy cow breeding.
    Type: Grant
    Filed: October 15, 2021
    Date of Patent: February 13, 2024
    Assignee: CHINA AGRICULTURAL UNIVERSITY
    Inventors: Guoshi Liu, Hao Wu, Yongqiang Lu, Lu Zhang, Hui Ma, Yi Chang, Qiaoxiang Liu, Songyang Yao, Pengyun Ji
  • Publication number: 20230255936
    Abstract: Provided is a method for reducing methane production in animal stomachs by adding melatonin to gastric juice of the animal or feeding the animal with melatonin. In the method of the present disclosure, 10?7 mol/L to 10?3 mol/L of melatonin can reduce the methane production from the in vitro gastric fermentation fluid, feeding melatonin of 8.0 to 35.0 mg/kg/day can reduce the methane production from the animal respiration from day 7 of feeding melatonin. The method of the present disclosure can reduce greenhouse gas emissions of animals, control environmental pollution and realize low-carbon farming.
    Type: Application
    Filed: February 1, 2023
    Publication date: August 17, 2023
    Inventors: Guoshi LIU, Yao FU, Songyang YAO, Xiao MA, Haiying YU, Yujun YAO, Dongying LV, Shengyu GUAN
  • Publication number: 20220117940
    Abstract: Disclosed is a composition for increasing pregnancy rate in ruminants exposed to ovsynch and timed artificial insemination, and a preparation method and application thereof. The effective component of the composition is melatonin with a concentration of 10-20 mg/mL. The present disclosure proves through animal experiments that the use of the composition of the present disclosure in combination with the last injection of GnRH in an ovsynch and timed artificial insemination protocol for a ruminant can regulate the secretion of reproductive hormones in an animal body, increase the levels of luteinizing hormone (LH) and progesterone in pregnant females, and improve ovum quality and facilitate ovulation, thus increasing the pregnancy rate in ruminants exposed to ovsynch and timed artificial insemination.
    Type: Application
    Filed: October 15, 2021
    Publication date: April 21, 2022
    Inventors: Guoshi LIU, Hao WU, Lu ZHANG, Yongqiang LU, Tiankun WANG, Jiangpeng GUO, Songyang YAO, Shengyu GUAN, Pengyun JI
  • Publication number: 20220117939
    Abstract: The disclosure discloses a composition containing melatonin as an effective ingredient, and its application in improving DHI production performance and improving milk quality. The composition containing melatonin as an effective ingredient according to the present disclosure can significantly reduce the somatic cell count in milk and improve milk quality. Under the conditions of different seasons, ages, and lactation periods, the administration of the composition containing melatonin as an active ingredient according to the present disclosure can significantly reduce the somatic cell score of cow milk (p<0.01), increase the protein content and lactose content in milk, and meanwhile reduce the fat content and urea nitrogen content in milk. In summary, the composition containing melatonin as an effective ingredient according to the present disclosure can improve the quality of milk and increase the efficiency of dairy cow breeding.
    Type: Application
    Filed: October 15, 2021
    Publication date: April 21, 2022
    Inventors: Guoshi LIU, Hao WU, Yongqiang LU, Lu ZHANG, Hui MA, Yi CHANG, Qiaoxiang LIIU, Songyang YAO, Pengyun JI
  • Publication number: 20210106559
    Abstract: Provided are an antioxidant complex for reducing the number of somatic cells in a livestock animal and a preparation method and application thereof. Active components of the preparation are melatonin (MT) having a centration of 2-30 g/L and vitamin C having a concentration of 1-14.3 g/L. The antioxidant complex provided in the present invention can effectively reduce the number of somatic cells in a diary cow and improve milk quality.
    Type: Application
    Filed: October 23, 2020
    Publication date: April 15, 2021
    Inventor: Guoshi LIU
  • Patent number: 10828277
    Abstract: Provided are an antioxidant complex for reducing the number of somatic cells in a livestock animal and a preparation method and application thereof. Active components of the preparation are melatonin (MT) having a centration of 2-30 g/L and vitamin C having a concentration of 1-14.3 g/L. The antioxidant complex provided in the present invention can effectively reduce the number of somatic cells in a diary cow and improve milk quality.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: November 10, 2020
    Assignee: China Agricultural University
    Inventor: Guoshi Liu
  • Publication number: 20170348281
    Abstract: Provided are an antioxidant complex for reducing the number of somatic cells in a livestock animal and a preparation method and application thereof. Active components of the preparation are melatonin (MT) having a centration of 2-30 g/L and vitamin C having a concentration of 1-14.3 g/L. The antioxidant complex provided in the present invention can effectively reduce the number of somatic cells in a diary cow and improve milk quality.
    Type: Application
    Filed: December 18, 2015
    Publication date: December 7, 2017
    Inventor: Guoshi LIU