Patents by Inventor Guowei SHU

Guowei SHU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12564618
    Abstract: An antihypertensive peptide probiotic goat milk powder and a preparation method thereof are provided. Goat milk is used as a raw material, the goat milk is sterilized and then cooled, and the screened probiotic bacteria for fermenting goat milk to produce antihypertensive peptides, namely Lacticaseibacillus rhamnosus KD5 (which is preserved in CCTCC on Sep. 7, 2023, with a preservation number of CCTCC NO: M20231641), is added and stirred evenly, and then fermented at a constant temperature. After the fermentation is completed, probiotic fermented goat milk containing antihypertensive peptides is obtained. After mixing the probiotic fermented goat milk evenly with or without nutritional fortifiers for middle-aged and elderly people, it is subjected to vacuum low-temperature spray-drying to obtain antihypertensive peptide probiotic goat milk powder, which has a high ACE inhibition rate and can be used to assist consumers in lowering blood pressure.
    Type: Grant
    Filed: May 15, 2025
    Date of Patent: March 3, 2026
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Guowei Shu, Ran Liang, Zongcai Zhang, Jianhao Nan, Huan Lei, Zhenquan Huo, Qiannan Kong, Chunji Dai, Zipei Xie
  • Patent number: 12539315
    Abstract: A sleep-aiding probiotic goat milk powder and a preparation method thereof are provided. Goat milk is used as the raw material, and the goat milk is sterilized and cooled, then inoculated with Limosilactobacillus fermentum KD6, which produces the sleep-aiding functional factor ?-aminobutyric acid. The strain was deposited in the China Center for Type Culture Collection (CCTCC) on Sep. 7, 2023, with the deposit number CCTCC NO: M20231642. After being stirred evenly, the mixture is fermented at a constant temperature without the need to add precursors of ?-aminobutyric acid such as glutamic acid or sodium glutamate. Upon completion of fermentation, probiotic fermented goat milk containing ?-aminobutyric acid is obtained, and is then subjected to vacuum low-temperature spray drying to obtain the functional sleep-aiding probiotic goat milk powder.
    Type: Grant
    Filed: May 30, 2025
    Date of Patent: February 3, 2026
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Guowei Shu, Anxin Mao, Guoliang Li, Qiqi Zheng, Qisheng Hu, Xinru Yu, Xu Zhang, Shiru Deng, Qian Wang, Qinfeng Xu
  • Publication number: 20250375500
    Abstract: An antihypertensive peptide probiotic goat milk powder and a preparation method thereof are provided. Goat milk is used as a raw material, the goat milk is sterilized and then cooled, and the screened probiotic bacteria for fermenting goat milk to produce antihypertensive peptides, namely Lacticaseibacillus rhamnosus KD5 (which is preserved in CCTCC on Sep. 7, 2023, with a preservation number of CCTCC NO: M20231641), is added and stirred evenly, and then fermented at a constant temperature. After the fermentation is completed, probiotic fermented goat milk containing antihypertensive peptides is obtained. After mixing the probiotic fermented goat milk evenly with or without nutritional fortifiers for middle-aged and elderly people, it is subjected to vacuum low-temperature spray-drying to obtain antihypertensive peptide probiotic goat milk powder, which has a high ACE inhibition rate and can be used to assist consumers in lowering blood pressure.
    Type: Application
    Filed: May 15, 2025
    Publication date: December 11, 2025
    Inventors: Guowei Shu, Ran Liang, Zongcai Zhang, Jianhao Nan, Huan Lei, Zhenquan Huo, Qiannan Kong, Chunji Dai, Zipei Xie
  • Publication number: 20250375482
    Abstract: A sleep-aiding probiotic goat milk powder and a preparation method thereof are provided. Goat milk is used as the raw material, and the goat milk is sterilized and cooled, then inoculated with Limosilactobacillus fermentum KD6, which produces the sleep-aiding functional factor ?-aminobutyric acid. The strain was deposited in the China Center for Type Culture Collection (CCTCC) on Sep. 7, 2023, with the deposit number CCTCC NO: M20231642. After being stirred evenly, the mixture is fermented at a constant temperature without the need to add precursors of ?-aminobutyric acid such as glutamic acid or sodium glutamate. Upon completion of fermentation, probiotic fermented goat milk containing ?-aminobutyric acid is obtained, and is then subjected to vacuum low-temperature spray drying to obtain the functional sleep-aiding probiotic goat milk powder.
    Type: Application
    Filed: May 30, 2025
    Publication date: December 11, 2025
    Inventors: Guowei SHU, Anxin MAO, Guoliang LI, Qiqi ZHENG, Qisheng HU, Xinru YU, Xu ZHANG, Shiru DENG, Qian WANG, Qinfeng XU
  • Patent number: 12312580
    Abstract: A strain of selenium-enriched Lactiplantibacillus plantarum KD-2 and applications in fermented goat milk and goat milk powder are provided in the present disclosure. The strain is preserved in China Center for Type Culture Collection on Apr. 13, 2023, with a deposit number of CCTCC NO: M2023478. The Lactiplantibacillus plantarum KD-2 is capable of reducing sodium selenite under a condition of buffer solution to prepare nano-selenium, which does not need to be carried out in a culture medium. The Lactiplantibacillus plantarum KD-2 is used to prepare selenium-enriched probiotic fermented goat milk, selenium-enriched probiotics and nano-selenium, and the selenium-enriched probiotics and nano-selenium are applied to goat milk powder.
    Type: Grant
    Filed: June 10, 2024
    Date of Patent: May 27, 2025
    Assignee: Shaanxi Yatai Dairy Co., Ltd.
    Inventors: Guowei Shu, Guoliang Li, Hongchang Wan, Xi'e Cheng, Meng Zhang, Jiaxin Li
  • Patent number: 12290541
    Abstract: Disclosed are a strain of Lactobacillus helveticus capable of removing multiple heavy metals and an application thereof in milk powder, where the strain is Lactobacillus helveticus KD-3, which is deposited in the China Center for Type Culture Collection on Apr. 6, 2023, with a deposit number of CCTCC NO: M2023479. The Lactobacillus helveticus KD-3 has a cadmium resistant gene czcD, a chromium resistant gene chrA and a lead resistant gene pbrT, and is capable of tolerating single and compound heavy metals (cadmium, chromium and lead). The Lactobacillus helveticus KD-3 of the present disclosure is used to prepare lyophilized bacterial powder.
    Type: Grant
    Filed: August 20, 2024
    Date of Patent: May 6, 2025
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Guowei Shu, Ke Zhang, Huan Lei, Qisheng Hu, Guanli Du, Qiqi Zheng, Guoliang Li, Qinfeng Xu, Chunji Dai, Ting Li, Wenjing Hu, Lihao Xu, Chaowei Yang, Jie Qiao
  • Publication number: 20250064872
    Abstract: Disclosed are a strain of Lactobacillus helveticus capable of removing multiple heavy metals and an application thereof in milk powder, where the strain is Lactobacillus helveticus KD-3, which is deposited in the China Center for Type Culture Collection on Apr. 6, 2023, with a deposit number of CCTCC NO: M2023479. The Lactobacillus helveticus KD-3 has a cadmium resistant gene czcD, a chromium resistant gene chrA and a lead resistant gene pbrT, and is capable of tolerating single and compound heavy metals (cadmium, chromium and lead). The Lactobacillus helveticus KD-3 of the present disclosure is used to prepare lyophilized bacterial powder.
    Type: Application
    Filed: August 20, 2024
    Publication date: February 27, 2025
    Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Guowei SHU, Ke ZHANG, Huan LEI, Qisheng Hu, Guanli DU, Qiqi ZHENG, Guoliang LI, Qinfeng XU, Chunji DAI, Ting LI, Wenjing HU, Lihao XU, Chaowei YANG, Jie QIAO
  • Publication number: 20240417676
    Abstract: A strain of selenium-enriched Lactiplantibacillus plantarum KD-2 and applications in fermented goat milk and goat milk powder are provided in the present disclosure. The strain is preserved in China Center for Type Culture Collection on Apr. 13, 2023, with a deposit number of CCTCC NO: M2023478. The Lactiplantibacillus plantarum KD-2 is capable of reducing sodium selenite under a condition of buffer solution to prepare nano-selenium, which does not need to be carried out in a culture medium. The Lactiplantibacillus plantarum KD-2 is used to prepare selenium-enriched probiotic fermented goat milk, selenium-enriched probiotics and nano-selenium, and the selenium-enriched probiotics and nano-selenium are applied to goat milk powder.
    Type: Application
    Filed: June 10, 2024
    Publication date: December 19, 2024
    Inventors: Guowei SHU, Guoliang LI, Hongchang WAN, Xi'e CHENG, Meng ZHANG, Jiaxin LI