Patents by Inventor Guoyu Liu

Guoyu Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ONCOLYTIC HERPES SIMPLEX VIRUS VECTORS EXPRESSING IMMUNE SYSTEM-STIMULATORY MOLECULES
    Publication number: 20250243252
    Abstract: An HSV vector comprising an expression cassette for one or more of IL12, IL15, and hIL15Receptor alpha subunit is provided.
    Type: Application
    Filed: December 9, 2024
    Publication date: July 31, 2025
    Inventors: William Jia, Guoyu Liu, Erica Lee, Dmitry Chouljenko, Jun Ding
  • Method for preparing high viscosity index poly-alpha-olefin
    Patent number: 12365848
    Abstract: A method for preparing a high viscosity index poly-?-olefin subjects ?-olefin to a polymerization reaction in the presence of a metallocene catalyst to obtain a poly-?-olefin. The polymerization reaction is carried out in the absence of a solvent, and the metallocene catalyst is formed of, or is formed by interaction between, a metallocene compound and an activator.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: July 22, 2025
    Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD.
    Inventors: Zhaolin Yin, Yucai Cao, Dongwen Zhong, Shengbiao Liang, Yongqing Li, Zhenyu Liu, Lujian Li, Xiaofeng Ye, Weizhe Wang, Chen Ni, Jie Li, Fan Wang, Guoyu Liu, Shibing Chen, Xionghua Chen, Wenjun Jiang, Zhenxu Lu, Si Tan, Ruizhen Lu
  • Oncolytic herpes simplex virus vectors expressing immune system-stimulatory molecules
    Patent number: 12162919
    Abstract: An HSV vector comprising an expression cassette for one or more of IL12, IL15, and hIL15Receptor alpha subunit is provided.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: December 10, 2024
    Assignee: Virogin Biotech Canada Ltd
    Inventors: William Jia, Guoyu Liu, Erica Lee, Dmitry Chouljenko, Jun Ding
  • HSV VECTORS WITH ENHANCED REPLICATION IN CANCER CELLS
    Publication number: 20230365994
    Abstract: An oncolytic HSV vector comprising an NF-?B response element or an Oct-3/4-SOX2 response element in a regulatory region of a viral gene that affects viral replication efficiency.
    Type: Application
    Filed: April 23, 2023
    Publication date: November 16, 2023
    Inventors: William Jia, Dmitry Chouljenko, Xuexian Bu, Guoyu Liu
  • METHOD FOR PREPARING HIGH VISCOSITY INDEX POLY-ALPHA-OLEFIN
    Publication number: 20220403278
    Abstract: A method for preparing a high viscosity index poly-?-olefin subjects ?-olefin to a polymerization reaction in the presence of a metallocene catalyst to obtain a poly-?-olefin. The polymerization reaction is carried out in the absence of a solvent, and the metallocene catalyst is formed of, or is formed by interaction between, a metallocene compound and an activator.
    Type: Application
    Filed: October 30, 2020
    Publication date: December 22, 2022
    Inventors: Zhaolin YIN, Yucai CAO, Dongwen ZHONG, Shengbiao LIANG, Yongqing LI, Zhenyu LIU, Lujian LI, Xiaofeng YE, Weizhe WANG, Chen NI, Jie LI, Fan WANG, Guoyu LIU, Shibin CHEN, Xionghua CHEN, Wenjun JIANG, Zhenxu LU, Si TAN, Ruizhen LU
  • HUMIDIFICATION FILTER SCREEN STRUCTURE AND PURIFIER
    Publication number: 20220120470
    Abstract: The present application discloses a humidification filter screen structure and a purifier, in particular, the purifier includes an air duct and a water tank arranged outside the air duct, and the humidification filter screen structure includes a cover body and a humidification filter screen assembly; the cover body includes an upper cover and a lower cover which are detachably connected, and the upper cover and the lower cover mutually enclose an mounting space; the humidification filter screen assembly is mounted in the mounting space, and the humidification filter screen assembly includes a water absorbing part and a humidification part which are connected with each other, the water absorbing part extends into the water tank, and the humidification part is communicated with the air duct.
    Type: Application
    Filed: December 29, 2018
    Publication date: April 21, 2022
    Inventors: Jihua HUANG, Gaoyuan LIU, Guoyu LIU
  • HSV VECTOR WITH REDUCED NEUROTOXICITY
    Publication number: 20200171110
    Abstract: Recombinant herpes simplex viruses are provided having a modified oncolytic herpes virus genome, wherein the modified herpes virus genome has at least one miRNA target sequence operably linked to a first or to a first and a second copy of an ICP34.5 gene. Also provided are pharmaceutical compositions having such recombinant herpes simplex viruses, as well as methods of using such compositions in the treatment of subjects having cancer.
    Type: Application
    Filed: November 29, 2019
    Publication date: June 4, 2020
    Inventors: William Jia, Dmitry V. Chouljenko, I-Fang Lee, Yanal M. Murad, Xiaohu Liu, Guoyu Liu, Xuexian Bu, Zahid Delwar
  • ONCOLYTIC HERPES SIMPLEX VIRUS VECTORS EXPRESSING IMMUNE SYSTEM-STIMULATORY MOLECULES
    Publication number: 20190169253
    Abstract: An HSV vector comprising an expression cassette for one or more of IL12, IL15, and hIL15Receptor alpha subunit is provided.
    Type: Application
    Filed: August 1, 2017
    Publication date: June 6, 2019
    Applicant: VIROGIN BIOTECH CANADA LTD
    Inventors: William Jia, Guoyu Liu, Erica Lee, Dmitry Chouljenko, Jun Ding
  • HSV VECTORS WITH ENHANCED REPLICATION IN CANCER CELLS
    Publication number: 20190106709
    Abstract: An oncolytic HSV vector comprising an NF-?B response element or an Oct-3/4-SOX2 response element in a regulatory region of a viral gene that affects viral replication efficiency.
    Type: Application
    Filed: April 29, 2017
    Publication date: April 11, 2019
    Inventors: William Jia, Dmitry Chouljenko, Xuexian Bu, Guoyu Liu
  • Set of eyeliner stencil
    Patent number: D1001367
    Type: Grant
    Filed: June 8, 2023
    Date of Patent: October 10, 2023
    Inventor: Guoyu Liu