Abstract: The present disclosure relates to the field of display technology, and in particular relates to a light shielding structure and a laser device. The light shielding structure comprises a first light shielding plate group and a second light shielding plate group, each of the first light shielding plate group and the second light shielding plate group comprises at least one light shielding plate, and the at least one light shielding plate can be moved relatively for forming at least two light transmitting regions. The light shielding structure can realize partial scanning of multiple target regions at a time, thereby saving production time, increasing production efficiency, saving water and electricity and other resources, and prolonging the laser lifetime.

Abstract: A subgroup B recombinant human adenovirus vector Ad11-5EP (SEQ ID NO: 1), which is constructed by a method including: substituting a 365 bp fragment containing an enhancer and a promoter of an upstream coding sequence of Ad5 E1A (SEQ ID NO: 2) for a corresponding region of a serotype Ad11 (SEQ ID NO: 3) of a subgroup B human adenovirus vector by homologous recombination to construct the subgroup B recombinant human adenovirus vector Ad11-5EP (SEQ ID NO: 1).

Abstract: The present disclosure relates to the field of display technology, and in particular relates to a light shielding structure and a laser device. The light shielding structure comprises a first light shielding plate group and a second light shielding plate group, each of the first light shielding plate group and the second light shielding plate group comprises at least one light shielding plate, and the at least one light shielding plate can be moved relatively for forming at least two light transmitting regions. The light shielding structure can realize partial scanning of multiple target regions at a time, thereby saving production time, increasing production efficiency, saving water and electricity and other resources, and prolonging the laser lifetime.

Abstract: A subgroup B recombinant human adenovirus vector Ad11-5EP (SEQ ID NO: 1), which is constructed by a method including: substituting a 365 bp fragment containing an enhancer and a promoter of an upstream coding sequence of Ad5 E1A (SEQ ID NO: 2) for a corresponding region of a serotype Ad11 (SEQ ID NO: 3) of a subgroup B human adenovirus vector by homologous recombination to construct the subgroup B recombinant human adenovirus vector Ad11-5EP (SEQ ID NO: 1).

Abstract: A method for reconstructing a replication-selective oncolytic adenovirus using a subgroup B recombinant human adenovirus vector Ad11-5EP. The method includes: 1) deleting E1A CR2 gene and/or anti-apoptotic gene E1B 21K that is necessary for viability of an adenovirus in normal cells but not necessary in tumor cells; 2) inserting a tumor-specific promoter to drive the expression of E1A gene; 3) re-directing a cellular tropism of Ad11-5EP according to receptors on a tumor cell surface; or 4) allowing adenovirus to selectively replicate in tumor cells.

Abstract: A method for reconstructing a replication-selective oncolytic adenovirus using a subgroup B recombinant human adenovirus vector Ad11-5EP. The method includes: 1) deleting E1A CR2 gene and/or anti-apoptotic gene E1B 21K that is necessary for viability of an adenovirus in normal cells but not necessary in tumor cells; 2) inserting a tumor-specific promoter to drive the expression of E1A gene; 3) re-directing a cellular tropism of Ad11-5EP according to receptors on a tumor cell surface; or 4) allowing adenovirus to selectively replicate in tumor cells.

Abstract: A method for constructing a subgroup B recombinant human adenovirus vector Ad11-5EP. The method includes substituting a 365 bp fragment including an enhancer and a promoter of an upstream coding sequence of Ad5 E1A for a corresponding region of a serotype Ad11 of the subgroup B human adenovirus vector by homologous recombination to construct the subgroup B recombinant human adenovirus vector Ad11-5EP. A subgroup B recombinant human adenovirus vector Ad11-5EP constructed by the method and the use thereof for treatment of tumors are also provided.

Abstract: A method for constructing a subgroup B recombinant human adenovirus vector Ad11-5EP. The method includes substituting a 365 bp fragment including an enhancer and a promoter of an upstream coding sequence of Ad5 E1A for a corresponding region of a serotype Ad11 of the subgroup B human adenovirus vector by homologous recombination to construct the subgroup B recombinant human adenovirus vector Ad11-5EP. A subgroup B recombinant human adenovirus vector Ad11-5EP constructed by the method and the use thereof for treatment of tumors are also provided.

Abstract: An oncolytic adenovirus vector and its potential application in cancer treatment and vaccination. The inventive vector (named Ad-TD-hIL12) is derived from the human adenovirus group C type 5, more particularly including deletion of three adenovirus genes E1A-CR2, E1B19K and E3gp-19K, and a fused cDNA sequence of p35 and p40 subunit of human IL12 placed under the control of the E3gp-19K promoter. The invention also includes a method to construct the triple gene-deleted vector (Ad-TD). The Ad-TD-hIL12 and Ad-TD-shIL12 (with a short p40 sequence of human IL 12) vectors can be used as targeted, genetically engineered agents for treatment of various solid tumors, via not only intratumoral injection, and also in intraperitoneal injection, without causing significant side effects, showing a superior antitumor efficacy and safety.

Abstract: Disclosed is a method for making a bioreactor comprising a foreign target gene, special selectable markers and Dunaliella Salina as host. It is prepared by the genetic transformation techniques that include introducing a foreign target gene into the cells of Dunaliella Salina and screening the transformed cells of Dunaliella Salina. The bioreactor of the present invention can be used as a safe and cheap production system for proteins of pharmaceutical interest including vaccines, especially oral products, in a large scale, because the cells of Dunaliella Salina are easy of genetic manipulation in preparation of the bioreactor, nontoxic and edible for humans and animals, and harmless to the environment.

Abstract: The present invention relates generally to the field on antennas and more specifically, to a low profile horizontally polarized sector antenna. The antenna includes a printed circuit board that has a dielectric substrate provided with a pair of first and second opposed faces and at least one dipole element formed on the dielectric substrate. The at least one dipole element has a pair of first and second, oppositely extending, dipole arms. The first dipole arm is formed on the first face of the dielectric substrate and the second dipole arm is formed on the second face thereof. The at least one dipole element has a width W corresponding to the span between the first and second dipole arms. The printed circuit board is also provided with a feed network that is operatively connected to the at least one dipole element. The antenna further includes a pair of conductive boards mounted to the dielectric substrate to stand proud of the second face thereof.

Abstract: A slot antenna comprising: a first and second boards each having an edge attached to respective opposite edges of a center board to form an essentially C-shaped open-ended channel having an inner surface and an outer surface; the center board having a slot for radiating signals defined in an electrically conductive layer bonded to an outer surface thereof and an electrically conductive feed line bonded to an inner surface thereof; the slot having a drive point being a portion of the feed line undercrossing the slot between opposite edges of the slot; the first and second boards each having an electrically conductive layer bonded to an outer surface thereof to reduce nulls, thereby providing an essentially omni-directional radiation pattern for the slot; and, a connector for coupling the signals to the antenna.

Abstract: A slot antenna comprising: a first and second boards each having an edge attached to respective opposite edges of a center board to form an essentially C-shaped open-ended channel having an inner surface and an outer surface; the center board having a slot for radiating signals defined in an electrically conductive layer bonded to an outer surface thereof and an electrically conductive feed line bonded to an inner surface thereof; the slot having a drive point being a portion of the feed line undercrossing the slot between opposite edges of the slot; the first and second boards each having an electrically conductive layer bonded to an outer surface thereof to reduce nulls, thereby providing an essentially omni-directional radiation pattern for the slot; and, a connector for coupling the signals to the antenna.

Abstract: Disclosed is a method for making a bioreactor comprising a foreign target gene, special selectable markers and Dunaliella Salina as host. It is prepared by the genetic transformation techniques that include introducing a foreign target gene into the cells of Dunaliella Salina and screening the transformed cells of Dunaliella Salina. The bioreactor of the present invention can be used as a safe and cheap production system for proteins of pharmaceutical interest including vaccines, especially oral products, in a large scale, because the cells of Dunaliella Salina are easy of genetic manipulation in preparation of the bioreactor, nontoxic and edible for humans and animals, and harmless to the environment.

Abstract: A high gain printed loop antenna comprises a first and second loop arranged symmetrically about a feed network, wherein each of the loops include pairs of substantially parallel radiation sections which when excited in phase from the feed network improves the gain of the antenna. Each of the parallel radiation sections are joined by patch elements such that the width of the patch elements is greater than the width of other portions of the loop. Thus, the patch elements allow for an increased variance in the path of a surface current through the loop.

Abstract: A high gain printed loop antenna comprises a first and second loop arranged symmetrically about a feed network wherein each of the loops include pairs of somewhat parallel radiation sections which may be excited in phase from the feed network to thereby improve the gain of the antenna.