Patents by Inventor Gurol Tuncman

Gurol Tuncman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210171599
    Abstract: The present invention provides a method to identify and use compounds for the inhibition of abnormal or dysregulated hepatic glucose production that results in elevated blood glucose levels and associated metabolic disorders. The invention is based on the surprising discovery that the glucagon forms an obligate binding complex with aP2, which is necessary for activation of the glucagon G-coupled protein receptor.
    Type: Application
    Filed: July 23, 2020
    Publication date: June 10, 2021
    Applicants: President and Fellows of Harvard College, The Brigham and Women's Hospital, Inc.
    Inventors: Gokhan S. Hotamisligil, Ediz Calay, Amir Tirosh, Gurol Tuncman, Motohiro Sekiya
  • Publication number: 20190135888
    Abstract: The present invention provides a method to identify and use compounds for the inhibition of abnormal or dysregulated hepatic glucose production that results in elevated blood glucose levels and associated metabolic disorders. The invention is based on the surprising discovery that the glucagon forms an obligate binding complex with aP2, which is necessary for activation of the glucagon G-coupled protein receptor.
    Type: Application
    Filed: December 20, 2018
    Publication date: May 9, 2019
    Applicant: President and Fellows of Harvard College
    Inventors: Gokhan S. Hotamisligil, Ediz Calay, Amir Tirosh, Gurol Tuncman, Motohiro Sekiya