Patents by Inventor Guru Reddy

Guru Reddy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline forms of a quinazoline compound and its hydrochloride salts
    Patent number: 11883402
    Abstract: This patent document relates to the crystalline forms of a quinazoline compound and the hydrochloride salts thereof. More particularly, this patent document relates to a preparation method of the crystalline forms of 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)prop-2-en-1-one and its hydrochloride salts.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: January 30, 2024
    Assignees: Hanmi Pharmaceutical Co., Ltd., Spectrum Pharmaceuticals, Inc.
    Inventors: Jong Ouk Baek, Hee Cheol Kim, Tae Hee Ha, Kweehyun Suh, Guru Reddy
  • Poziotinib Combination with VEGFR2 Inhibitors and Methods of Use Thereof
    Publication number: 20220296598
    Abstract: A drug combination containing poziotinib or a pharmaceutically acceptable salt thereof and a VEGFR2 inhibitor and methods of using the combination for treating cancer in a subject in need thereof. The drug combination demonstrates synergistic effect in treating cancers having one or more EGFR or HER2 mutations.
    Type: Application
    Filed: August 21, 2020
    Publication date: September 22, 2022
    Applicant: Spectrum Pharmaceuticals, Inc.
    Inventor: Guru Reddy
  • Combination therapy using belinostat and pralatrexate to treat lymphoma
    Patent number: 11439643
    Abstract: The present invention relates to compositions and methods for treating lymphoma in a subject in need thereof, said methods comprising administering to the patient in need thereof a therapeutically effective amount of a combination of belinostat and pralatrexate, wherein said therapeutically effective amount results in a synergistic antiproliferative effect on cancer cell growth.
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: September 13, 2022
    Assignee: Acrotech Biopharma Inc.
    Inventor: Guru Reddy
  • KITS AND METHODS FOR TREATING CANCERS
    Publication number: 20220040180
    Abstract: A kit containing a crystalline form of a quinazoline compound. More particularly, the crystalline form is derived from the compound of 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)prop-2-en-1-one. Also disclosed is a method of treating cancers with the crystalline form or a kit thereof.
    Type: Application
    Filed: September 12, 2019
    Publication date: February 10, 2022
    Inventor: Guru Reddy
  • POZIOTINIB COMBINATIONS WITH AN ANTI-HER1, HER2 OR HER4 ANTIBODY AND METHODS OF USE THEREOF
    Publication number: 20210260064
    Abstract: Provided are combinations of poziotinib and an anti-HER1, anti-HER2 or anti-HER4 antibody, optionally with other agents, and use of the combinations for treating cancer.
    Type: Application
    Filed: June 25, 2019
    Publication date: August 26, 2021
    Inventors: Guru Reddy, Sunyoung Jang, Jooyun Byun
  • COMBINATION OF POZIOTINIB WITH CYTOTOXIC AGENT AND/OR OTHER MOLECULARLY TARGETED AGENT AND USE THEREOF
    Publication number: 20210145834
    Abstract: Provided are a combination of poziotinib and at least one agent selected from the group consisting of cytotoxic agents and molecularly targeted agents; and a use of the combination.
    Type: Application
    Filed: June 25, 2019
    Publication date: May 20, 2021
    Inventor: Guru Reddy
  • COMBINATION THERAPY USING BELINOSTAT AND PRALATREXATE TO TREAT LYMPHOMA
    Publication number: 20180177783
    Abstract: The present invention relates to compositions and methods for treating lymphoma in a subject in need thereof, said methods comprising administering to the patient in need thereof a therapeutically effective amount of a combination of belinostat and pralatrexate, wherein said therapeutically effective amount results in a synergistic antiproliferative effect on cancer cell growth.
    Type: Application
    Filed: June 14, 2016
    Publication date: June 28, 2018
    Applicant: Spectrum Pharmaceuticals, Inc.
    Inventor: Guru Reddy
  • Bladder cancer treatment and methods
    Patent number: 9295666
    Abstract: Therapeutic compositions comprising an indoloquinone compound and various bladder cancer treatments and methods are disclosed. More specifically, the compositions comprise an indoloquinone compound and a formulation vehicle. The formulation vehicle improves the solubility and stability of the indoloquinone compound. Additionally, the coating compositions can include coating agents that provide better adhesion of the coating composition to the bladder wall during intravesical delivery of the coating composition.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: March 29, 2016
    Assignee: Spectrum Pharmaceuticals, Inc.
    Inventors: Bastiaan Nuijen, Ernie Pfadenhauer, Jos H. Beijnen, Dorla Mirejovsky, Guru Reddy, Luigi Lenaz
  • Thioxanthone-based autophagy inhibitor therapies to treat cancer
    Patent number: 9000031
    Abstract: The present specification provides compositions comprising a thioxanthone-based autophagy inhibitor and/or a cancer therapeutic autophagy inducing compound, pharmaceutical kits comprising these compositions, and methods of treating cancer using such compounds, compositions and kits. Additionally, the present specification provides methods of treating cancer using a thioxanthone-based autophagy inhibitor and a radiotherapy.
    Type: Grant
    Filed: August 6, 2013
    Date of Patent: April 7, 2015
    Assignee: Spectrum Pharmaceuticals, Inc.
    Inventors: Steffan Nawrocki, Jennifer Carew, Guru Reddy
  • Sensitization of tumor cells to radiation therapy through administration of endothelin agonists
    Patent number: 8957014
    Abstract: Methods to sensitize tumor cells to radiation therapy through the administration of an endothelin agonist such as the ETB agonist IRL1620.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: February 17, 2015
    Assignees: Spectrum Pharmaceuticals, Inc., The Board of Trustees of the University of Illinoise
    Inventors: Anil Gulati, Guru Reddy, Luigi Lenaz
  • Methods, compositions and articles of manufacture for contributing to the treatment of cancers
    Patent number: 8729023
    Abstract: Methods, compositions and articles of manufacture for contributing to the treatment of cancers, including solid tumors, are disclosed. The methods, compositions and articles of manufacture can utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of a chemotherapeutic agent.
    Type: Grant
    Filed: December 11, 2012
    Date of Patent: May 20, 2014
    Assignees: Spectrum Pharmaceuticals, Inc., The Board of Trustees of the University of Illinois
    Inventors: Anil Gulati, Guru Reddy, Luigi Lenaz
  • Thioxanthone-Based Autophagy Inhibitor Therapies to Treat Cancer
    Publication number: 20140106003
    Abstract: The present specification provides compositions comprising a thioxanthone-based autophagy inhibitor and/or a cancer therapeutic autophagy inducing compound, pharmaceutical kits comprising these compositions, and methods of treating cancer using such compounds, compositions and kits. Additionally, the present specification provides methods of treating cancer using a thioxanthone-based autophagy inhibitor and a radiotherapy.
    Type: Application
    Filed: August 6, 2013
    Publication date: April 17, 2014
    Applicant: SPECTRUM PHARMACEUTICALS, INC.
    Inventors: Steffan Nawrocki, Jennifer Carew, Guru Reddy
  • BLADDER CANCER TREATMENT AND METHODS
    Publication number: 20140073680
    Abstract: Therapeutic compositions comprising an indoloquinone compound and various bladder cancer treatments and methods are disclosed. More specifically, the compositions comprise an indoloquinone compound and a formulation vehicle. The formulation vehicle improves the solubility and stability of the indoloquinone compound. Additionally, the coating compositions can include coating agents that provide better adhesion of the coating composition to the bladder wall during intravesical delivery of the coating composition.
    Type: Application
    Filed: August 30, 2013
    Publication date: March 13, 2014
    Applicant: Spectrum Pharmaceuticals, Inc.
    Inventors: Bastiaan Nuijen, Ernie Pfadenhauer, Jos H. Beijnen, Dorla Mirejovsky, Guru Reddy, Luigi Lenaz
  • Methods and compositions for contributing to the treatment of cancers
    Patent number: 8642026
    Abstract: Methods and compositions for contributing to the treatment of cancers, especially ovarian tumors, are disclosed. The methods and compositions utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of chemotherapeutic agent(s) (e.g., cisplatin and/or cyclophosphamide).
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: February 4, 2014
    Assignees: Spectrum Pharmaceuticals, Inc., The Board of Trustees of the University of Illinois
    Inventors: Anil Gulati, Guru Reddy, Luigi Lenaz
  • Bladder cancer treatment and methods
    Patent number: 8563592
    Abstract: Therapeutic compositions comprising an indoloquinone compound and various bladder cancer treatments and methods are disclosed. More specifically, the compositions comprise an indoloquinone compound and a formulation vehicle. The formulation vehicle improves the solubility and stability of the indoloquinone compound. Additionally, the coating compositions can include coating agents that provide better adhesion of the coating composition to the bladder wall during intravesical delivery of the coating composition.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: October 22, 2013
    Assignee: Spectrum Pharmaceuticals, Inc.
    Inventors: Bastiaan Nuijen, Ernie Pfadenhauer, Jos H. Beijnen, Dorla Mirejovsky, Guru Reddy, Luigi Lenaz
  • Thioxanthone-based autophagy inhibitor therapies to treat cancer
    Patent number: 8524762
    Abstract: The present specification provides compositions comprising a thioxanthone-based autophagy inhibitor and/or a cancer therapeutic autophagy inducing compound, pharmaceutical kits comprising these compositions, and methods of treating cancer using such compounds, compositions and kits. Additionally, the present specification provides methods of treating cancer using a thioxanthone-based autophagy inhibitor and a radiotherapy.
    Type: Grant
    Filed: March 8, 2011
    Date of Patent: September 3, 2013
    Assignee: Spectrum Pharmaceuticals, Inc.
    Inventors: Steffan Nawrocki, Jennifer Carew, Guru Reddy
  • Methods, compositions and articles of manufacture for contributing to the treatment of cancers
    Patent number: 8440620
    Abstract: Methods, compositions and articles of manufacture for contributing to the treatment of cancers, including solid tumors, are disclosed. The methods, compositions and articles of manufacture can utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of a chemotherapeutic agent.
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: May 14, 2013
    Assignee: Spectrum Pharmaceuticals, Inc.
    Inventors: Anil Gulati, Guru Reddy, Luigi Lenaz
  • Sensitization of tumor cells to radiation therapy through the administration of endothelin agonists
    Patent number: 8394757
    Abstract: Methods to sensitize tumor cells to radiation therapy through the administration of an endothelin agonist such as the ETB agonist IRL1620.
    Type: Grant
    Filed: August 27, 2007
    Date of Patent: March 12, 2013
    Assignees: Spectrum Pharmaceuticals, Inc., The Board of Trustees of the University of Illinois
    Inventors: Anil Gulati, Guru Reddy, Luigi Lenaz
  • Methods and compositions for contributing to the treatment of cancers
    Patent number: 8349802
    Abstract: Methods and compositions for contributing to the treatment of cancers, especially ovarian tumors, are disclosed. The methods and compositions utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of chemotherapeutic agent(s) (e.g., cisplatin and/or cyclophosphamide).
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: January 8, 2013
    Assignee: Spectrum Pharmaceuticals, Inc.
    Inventors: Anil Gulati, Guru Reddy, Luigi Lenaz
  • Methods, Compositions and Articles of Manufacture for Contributing to the Treatment of Cancers
    Publication number: 20110315575
    Abstract: Methods, compositions and articles of manufacture for contributing to the treatment of cancers, including solid tumors, are disclosed. The methods, compositions and articles of manufacture can utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of a chemotherapeutic agent.
    Type: Application
    Filed: August 29, 2011
    Publication date: December 29, 2011
    Applicants: The Board of Trustees of the University of Illinois, Spectrum Pharmaceuticals, Inc.
    Inventors: Anil Gulati, Guru Reddy, Luigi Lenaz