Patents by Inventor Gurusingham Sitta Sittampalam

Gurusingham Sitta Sittampalam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING CHEMORESISTANT CANCER-INITIATING CELLS
    Publication number: 20220105114
    Abstract: The disclosure provides methods of treating cancer by selectively inhibiting p-S552-?-catenin, p-T217-?-catenin, T332-?-catenin, and/or p-S675-?-catenin production and/or activity. Such methods also and/or limit cancer-initiating cells.
    Type: Application
    Filed: October 12, 2021
    Publication date: April 7, 2022
    Inventors: Rajeswari KASI, Linheng Ll, Xiuling LU, John M. PERRY, Gurusingham Sitta SITTAMPALAM, Anuradha ROY, Xi C. HE
  • Methods for treating chemoresistant cancer-initiating cells
    Patent number: 11173173
    Abstract: The disclosure provides methods of treating cancer by selectively inhibiting p-S552-?-catenin, p-T217-?-catenin, p-T332-?-catenin, and/or p-S675-?-catenin production and/or activity. Such methods also and/or limit cancer-initiating cells.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: November 16, 2021
    Assignees: UNIVERSITY OF CONNECTICUT, UNIVERSITY OF KANSAS, STOWERS INSTITUTE FOR MEDICAL RESEARCH
    Inventors: Rajeswari Kasi, Linheng Li, Xiuling Lu, John M. Perry, Gurusingham Sitta Sittampalam, Anuradha Roy, Xi C. He
  • METHODS FOR TREATING CHEMORESISTANT CANCER-INITIATING CELLS
    Publication number: 20180207184
    Abstract: The disclosure provides methods of treating cancer by selectively inhibiting p-S552-?-catenin, p-T217-?-catenin, p-T332-?-catenin, and/or p-S675-?-catenin production and/or activity. Such methods also and/or limit cancer-initiating cells.
    Type: Application
    Filed: July 28, 2016
    Publication date: July 26, 2018
    Inventors: Rajeswari KASI, Linheng Ll, Xiuling LU, John M. PERRY, Gurusingham Sitta SITTAMPALAM, Anuradha ROY, Xi C. HE
  • In vitro tumor in dish kit and method
    Patent number: 9494573
    Abstract: This invention is a method and kit for preparing a Tumor in Dish model for use in screening anti-cancer agents and analyzing cancer growth and development.
    Type: Grant
    Filed: May 20, 2013
    Date of Patent: November 15, 2016
    Assignee: University of Kansas
    Inventors: Shrikant Anant, Prabhu Ramamoorthy, Satish Ramalingam, Gurusingham Sitta Sittampalam
  • IN VITRO TUMOR IN DISH KIT AND METHOD
    Publication number: 20130316392
    Abstract: This invention is a method and kit for preparing a Tumor in Dish model for use in screening anti-cancer agents and analyzing cancer growth and development.
    Type: Application
    Filed: May 20, 2013
    Publication date: November 28, 2013
    Inventors: Shrikant Anant, Prabhu Ramamoorthy, Satish Ramalingam, Gurusingham Sitta Sittampalam
  • SYSTEMS AND METHODS FOR MECHANICALLY STRAINED CELL CULTURE
    Publication number: 20130059324
    Abstract: A method for in vitro drug screening can include: providing one or more cells in vitro; introducing a chemical to the one or more cells; introducing a mechanical strain to the one or more cells in the presence of the chemical; and determining whether or not the chemical has bioactivity with respect to the one or more cells under the mechanical strain. The mechanical strain can be implemented with a well plate defining a plurality of cell culture wells and having one or more flexible substrates associated with the well plate so that each cell culture well has a fluid tight flexible cell culture substrate.
    Type: Application
    Filed: May 11, 2011
    Publication date: March 7, 2013
    Applicant: THE UNIVERSITY OF KANSAS
    Inventors: Gurusingham Sitta Sittampalam, Victor Sanjit Nirmalanandhan