Patents by Inventor Gustav E. Lienhard

Gustav E. Lienhard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for identifying agents which modulate GTPase activity involved in insulin-stimulated GLUT4 translocation
    Patent number: 7799538
    Abstract: The present invention is a method for identifying agents that modulate the GTPase activity of AS160. In the instant assay, AS160 or the GAP domain thereof is contacted with a test agent, in the presence of GTP-bound Rab (2A, 8A, 8B, 10, or 14), and the AS160 GAP domain-mediated hydrolysis of GTP to GDP is monitored.
    Type: Grant
    Filed: March 8, 2006
    Date of Patent: September 21, 2010
    Assignee: Trustees of Dartmouth College
    Inventors: Gustav E. Lienhard, Susan Kane, Cristinel P. Miinea, Hiroyuki Sano
  • Method For Identifying Agents Which Modulate GtpPase Activity Involved in Insulin-Stimulated Glut4 Translocation
    Publication number: 20080268487
    Abstract: The present invention is a method for identifying agents that modulate the GTPase activity of AS160. In the instant assay, AS160 or the GAP domain thereof is contacted with a test agent, in the presence of GTP-bound Rab (2A, 8A, 8B, 10, or 14), and the AS160 GAP domain-mediated hydrolysis of GTP to GDP is monitored.
    Type: Application
    Filed: March 8, 2006
    Publication date: October 30, 2008
    Applicant: TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: Gustav E. Lienhard, Susan Kane, Christinel P. Miinea, Hiroyuki Sano