Abstract: The present disclosure provides compounds of Formula I: (I), pharmaceutically acceptable salts thereof, conjugates thereof, as well as methods of synthesizing and using such compounds, e.g., in a method of treating a pathological condition in a subject. The compounds described herein can have immunomodulatory properties and can interact with a Toll-like receptor as described herein.

Abstract: A method performed by a first communication device for managing beamforming by a second communication device for transmission of a signal. The first and second communication devices operate in a wireless communications network having a zone in which a radio frequency electromagnetic field strength is required by a regulation to be below a threshold. The first communication device adjusts at least one of an output power and a beam shape in the beamforming. The adjusting is such that the radio frequency electromagnetic field strength in the zone for the output power and the beam shape in the beamforming is below the threshold. The first communication device initiates transmission of the signal to a third communication device operating in the wireless communications network using beamforming with the adjusted at least one of the output power and the beam shape.

Abstract: A method performed by a first communication device for managing beamforming by a second communication device for transmission of a signal. The first and second communication devices operate in a wireless communications network having a zone in which a radio frequency electromagnetic field strength is required by a regulation to be below a threshold. The first communication device adjusts at least one of an output power and a beam shape in the beamforming. The adjusting is such that the radio frequency electromagnetic field strength in the zone for the output power and the beam shape in the beamforming is below the threshold. The first communication device initiates transmission of the signal to a third communication device operating in the wireless communications network using beamforming with the adjusted at least one of the output power and the beam shape.

Abstract: The session-based server deployment can be comprised of an engine tier that is designed for high throughput processing of communications and a state tier that maintains state information for access by the engine tier. The engine tier can include a plurality of engine nodes that process incoming messages. The state nodes can contain call state, including various timers. When processing a call, an engine can set various timers in the state tier. Upon expiration of a timer, the state node can transmit a notification assigning the timer to the corresponding engine node which handled previous communications for the call. This affinity between the timer and its respective engine can provide numerous benefits, such as reduced latency and more localized data access.

Abstract: The session-based server deployment can be comprised of an engine tier that is designed for high throughput processing of communications and a state tier that maintains state information for access by the engine tier. The engine tier can include a plurality of engine nodes that process incoming messages. The state nodes can contain call state, including various timers. When processing a call, an engine can set various timers in the state tier. Upon expiration of a timer, the state node can transmit a notification assigning the timer to the corresponding engine node which handled previous communications for the call. This affinity between the timer and its respective engine can provide numerous benefits, such as reduced latency and more localized data access.