Patents by Inventor Gustavo Salguero-Lopez

Gustavo Salguero-Lopez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Induced dendritic cells and uses thereof
    Patent number: 11413307
    Abstract: The present invention relates to cells engineered to express at least one cytokine and at least one antigen which induces the self differentiation of dendritic cell (DC) progenitor cells into functional antigen-presenting induced DC (iDC). Moreover, therapeutic uses of said iDC for regenerating the immune system after transplantation of hematopoietic stem cells are disclosed. Said iDC are also useful for generating mice with a functional endogenously regenerated humanized immune system producing antigen-specific T and B cell responses which can be used as animal models for the study of the human adaptive immune responses.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: August 16, 2022
    Assignee: MEDIZINISCHE HOCHSCHULE HANNOVER
    Inventors: Renata Stripecke, Gustavo Salguero-Lopez, Anusara Daenthanasanmak, Arnold Ganser
  • INDUCED DENDRITIC CELLS AND USES THEREOF
    Publication number: 20190247430
    Abstract: The present invention relates to cells engineered to express at least one cytokine and at least one antigen which induces the self differentiation of dendritic cell (DC) progenitor cells into functional antigen-presenting induced DC (iDC). Moreover, therapeutic uses of said iDC for regenerating the immune system after transplantation of hematopoietic stem cells are disclosed. Said iDC are also useful for generating mice with a functional endogenously regenerated humanized immune system producing antigen-specific T and B cell responses which can be used as animal models for the study of the human adaptive immune responses.
    Type: Application
    Filed: April 26, 2019
    Publication date: August 15, 2019
    Inventors: Renata Stripecke, Gustavo Salguero-Lopez, Anusara Daenthanasanmak, Arnold Ganser
  • Induced dendritic cells and uses thereof
    Patent number: 10272111
    Abstract: The present invention relates to cells engineered to express at least one cytokine and at least one antigen which induces the self differentiation of dendritic cell (DC) progenitor cells into functional antigen-presenting induced DC (iDC). Moreover, therapeutic uses of said iDC for regenerating the immune system after transplantation of hematopoietic stem cells are disclosed. Said iDC are also useful for generating mice with a functional endogenously regenerated humanized immune system producing antigen-specific T and B cell responses which can be used as animal models for the study of the human adaptive immune responses.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: April 30, 2019
    Assignee: Medizinische Hochschule Hannover
    Inventors: Renata Stripecke, Gustavo Salguero-Lopez, Anusara Daenthanasanmak, Arnold Ganser
  • INDUCED DENDRITIC CELLS AND USES THEREOF
    Publication number: 20160038541
    Abstract: The present invention relates to cells engineered to express at least one cytokine and at least one antigen which induces the self differentiation of dendritic cell (DC) progenitor cells into functional antigen-presenting induced DC (iDC). Moreover, therapeutic uses of said iDC for regenerating the immune system after transplantation of hematopoietic stem cells are disclosed. Said iDC are also useful for generating mice with a functional endogenously regenerated humanized immune system producing antigen-specific T and B cell responses which can be used as animal models for the study of the human adaptive immune responses.
    Type: Application
    Filed: August 7, 2015
    Publication date: February 11, 2016
    Inventors: Renata Stripecke, Gustavo Salguero-Lopez, Anusara Daenthanasanmak, Arnold Ganser