Patents by Inventor Gusui Wu
Gusui Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240392310Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: July 25, 2024Publication date: November 28, 2024Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: NURIA JIMENEZ-JUAREZ, ALBERT L LU, LU LIU, MARK EDWARD NELSON, GUSUI WU
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Patent number: 12031143Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: January 31, 2023Date of Patent: July 9, 2024Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Albert L Lu, Knut Meyer, Gilda Rauscher, Gusui Wu
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Publication number: 20230340522Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: January 25, 2023Publication date: October 26, 2023Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: NURIA JIMENEZ-JUAREZ, ALBERT L LU, LU LIU, MARK EDWARD NELSON, GUSUI WU
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Publication number: 20230272018Abstract: The disclosure provides nucleic acids, and variants and fragments thereof, derived from strains of Bacillus thuringiensis encoding variant polypeptides having increased pesticidal activity against insect pests, including Lepidoptera and Coleopteran. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.Type: ApplicationFiled: October 17, 2022Publication date: August 31, 2023Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: ALBERT L. LU, MARK EDWARD NELSON, GUSUI WU, TAKASHI YAMAMOTO
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Publication number: 20230227843Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: January 31, 2023Publication date: July 20, 2023Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: ALBERT L LU, KNUT MEYER, GILDA RAUSCHER, GUSUI WU
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Patent number: 11193139Abstract: This disclosure relates to the field of molecular biology. Provided are novel genes that encode pesticidal proteins. These pesticidal proteins and the nucleic acid sequences that encode them are useful in preparing pesticidal formulations and in the production of transgenic pest-resistant plants. Methods to create or alter pesticidal proteins are provided for altered or enhanced pesticidal activity.Type: GrantFiled: December 18, 2019Date of Patent: December 7, 2021Assignees: Chinese Academy of Agricultural Sciences, Pioneer Hi-Bred International, Inc.Inventors: Jennifer Kara Barry, Thomas Chad Wolfe, Gusui Wu, Jian-Zhou Zhao, Yueming Shan, Changlong Shu, Jie Zhang
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Patent number: 11028407Abstract: The disclosure provides nucleic acids, and variants and fragments thereof, derived from strains of Bacillus thuringiensis encoding variant polypeptides having increased pesticidal activity against insect pests, including Lepidoptera and Coleopteran. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.Type: GrantFiled: April 19, 2017Date of Patent: June 8, 2021Inventors: Albert L Lu, Gusui Wu
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Patent number: 10876132Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with one or more nucleic acid sequence encoding insecticidal protein(s) and one or more silencing element(s). In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The molecular and breeding stacks find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: March 3, 2016Date of Patent: December 29, 2020Assignees: E I DU PONT DE NEMOURS AND COMPANYInventors: Scott Henry Diehn, Xu Hu, Albert L. Lu, Lu Liu, James Kevin Presnail, Gary A. Sandahl, Ute Schellenberger, Gusui Wu
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Publication number: 20200332314Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: November 29, 2018Publication date: October 22, 2020Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: ALBERT L LU, KNUT MEYER, GILDA RAUSCHER, GUSUI WU
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Publication number: 20200308598Abstract: The disclosure provides nucleic acids, and variants and fragments thereof, derived from strains of Bacillus thuringiensis encoding variant polypeptides having increased pesticidal activity against insect pests, including Lepidoptera and Coleopteran. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.Type: ApplicationFiled: April 18, 2018Publication date: October 1, 2020Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: ALBERT L LU, MARK EDWARD NELSON, GUSUI WU, TAKASHI YAMAMOTO
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Publication number: 20200224216Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: January 11, 2018Publication date: July 16, 2020Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: NURIA JIMENEZ-JUAREZ, ALBERT L LU, LU LIU, MARK EDWARD NELSON, GUSUI WU
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Publication number: 20200196612Abstract: This disclosure relates to the field of molecular biology. Provided are novel genes that encode pesticidal proteins. These pesticidal proteins and the nucleic acid sequences that encode them are useful in preparing pesticidal formulations and in the production of transgenic pest-resistant plants. Methods to create or alter pesticidal proteins are provided for altered or enhanced pesticidal activity.Type: ApplicationFiled: December 18, 2019Publication date: June 25, 2020Applicants: PIONEER HI-BRED INTERNATIONAL, INC., CHINESE ACADEMY OF AGRICULTURAL SCIENCESInventors: JENNIFER KARA BARRY, THOMAS CHAD WOLFE, GUSUI WU, JIAN-ZHOU ZHAO, YUEMING SHAN, CHANGLONG SHU, JIE ZHANG
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Publication number: 20200140882Abstract: The disclosure provides nucleic acids, and variants and fragments thereof, derived from strains of Bacillus thuringiensis encoding variant polypeptides having increased pesticidal activity against insect pests, including Lepidoptera and Coleopteran. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.Type: ApplicationFiled: April 19, 2017Publication date: May 7, 2020Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: ALBERT L LU, GUSUI WU
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Publication number: 20190390219Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding a silencing element and an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, Hemipteran, fungi and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: January 22, 2018Publication date: December 26, 2019Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: CHAD THOMAS BARRETT, XU HU, ALBERT L LU, LAURA J RUTTMAN, GUSUI WU
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Publication number: 20190292543Abstract: The present invention relates generally to methods of molecular biology and gene silencing to control pests.Type: ApplicationFiled: December 13, 2017Publication date: September 26, 2019Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: VIRGINIA CRANE, JOHN LINDSEY FLEXNER, XU HU, ADANE KASSA, ALBERT L. LU, XIPING NIU, ZAIQI PAN, AMIT SETHI, GUSUI WU
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Publication number: 20180042242Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with one or more nucleic acid sequence encoding insecticidal protein(s) and one or more silencing element(s). In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The molecular and breeding stacks find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: March 3, 2016Publication date: February 15, 2018Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: SCOTT HENRY DIEHN, XU HU, ALBERT L. LU, LU LIU, JAMES KEVIN PRESNAIL, GARY A. SANDAHL, UTE SCHELLENBERGER, GUSUI WU
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Publication number: 20160168587Abstract: The present invention comprises methods and compositions for controlling nematode parasitism in host plant. The present invention comprises novel polynucleotides and polypeptides encoded by such polynucleotides comprising one or more nucleic acid sequences disclosed herein having a nucleotide sequence comprising any one of SEQ ID NO: 1-142 or 161, a fragment or variant thereof, or a complement thereof, or a polypeptide sequence comprising any one of SEQ ID NO: 143-160, a fragment or variant thereof.Type: ApplicationFiled: March 12, 2014Publication date: June 16, 2016Inventors: Jun-Zhi Wei, Gusui Wu, Carl Simmons, Thomas Baum, Eric Davis, Richard Hussey, Melissa G. Mitchum
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Publication number: 20140275213Abstract: The present invention comprises methods and compositions for controlling nematode parasitism in host plant. The present invention comprises novel polynucleotides and polypeptides encoded by such polynucleotides comprising one or more nucleic acid sequences disclosed herein having a nucleotide sequence comprising any one of SEQ ID NOs: 1-142, a fragment or variant thereof, or a complement thereof, or a polypeptide sequence comprising any one of SEQ ID NOs: 143-159, a fragment or variant thereof.Type: ApplicationFiled: March 12, 2014Publication date: September 18, 2014Applicants: Pioneer Hi-Bred International, Inc., Iowa State University Research Foundation, Inc., The Curators of the University of Missouri, University of Georgia Research Foundation, Inc., North Carolina State UniversityInventors: Jun-zhi Wei, Gusui Wu, Carl R. Simmons, Thomas Baum, Eric Davis, Richard Hussey, Melissa G. Mitchum
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Patent number: 8735147Abstract: The invention provides novel cyclotide polypeptides, and variants and fragments thereof, obtained from Butterfly pea and having pesticidal activity against nematodes. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, biopesticide compositions, expression cassettes, and transformed microorganisms and plants comprising a nucleic acid of the invention. These compositions find use in methods for controlling pests, especially plant-parasitic pests such as nematodes and insects.Type: GrantFiled: April 4, 2012Date of Patent: May 27, 2014Assignee: Pioneer Hi Bred International IncInventors: Daniel J. Altier, Xuehua Hu, Daniel L. Siehl, Jun-Zhi Wei, Gusui Wu
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Publication number: 20130029844Abstract: The invention provides novel cyclotide polypeptides, and variants and fragments thereof, obtained from Butterfly pea and having pesticidal activity against nematodes. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, biopesticide compositions, expression cassettes, and transformed microorganisms and plants comprising a nucleic acid of the invention. These compositions find use in methods for controlling pests, especially plant-parasitic pests such as nematodes and insects.Type: ApplicationFiled: April 4, 2012Publication date: January 31, 2013Applicant: PIONEER HI BRED INTERNATIONAL INC.Inventors: Daniel J. Altier, Xuehua Hu, Daniel L. Siehl, Jun-Zhi Wei, Gusui Wu