Abstract: A personalized brain stimulation device includes: a sensor unit measuring biological information of an object; a control unit determining, based on the biological information of the object measured by the sensor unit, that the state of the object corresponds to a first state among a predetermined plurality of depression-related states; and a stimulation unit delivering a stimulus, which varies according to the determined first state, to the brain of the object to entrain synchronized oscillation in multiple regions of the brain of the object, wherein the stimulus is a first stimulus to entrain gamma oscillation synchronized in multiple regions of the brain, a second stimulus to entrain any one of delta, theta, alpha, and beta oscillation synchronized in multiple regions of the brain, or a third stimulus that combines the first stimulus and the second stimulus, wherein the first, second, and third stimulus are an transcranial alternating current stimulation.

Abstract: An apparatus includes a stimulation part that stimulates a brain of an object; a sensing part that measures a response of the brain to a stimulation; and a control part that determines whether a first response entraining oscillation synchronized in a plurality of brain areas of the object is derived or not, based on a measured brain response. The stimulation part is an electrical stimulation part that transfers a transcranial alternating current stimulation (tACS) and the transcranial alternating current stimulation is a first combined stimulation in which a signal is repeatedly ON/ OFF according to a predetermined first frequency and an ON signal according to the first frequency is applied as a stimulation according to a predetermined second frequency.