Patents by Inventor Guy Bodson

Guy Bodson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4943639
    Abstract: (S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide, its preparation and pharmaceutical compositions containing the same. It can be prepared either by reacting (S)-alpha-ethyl-2-oxo-1-pyrrolidineacetic acid successively with an alkyl haloformate and with ammonia, or, by cyclizing an (S)-2-amino-butanamide of the formula X--CH.sub.2 CH.sub.2 --Y--NHCH(C.sub.2 H.sub.5)CONH.sub.2 wherein Y is a --CH.sub.2 -- radical when X represents a ZOOC-- radical and Y is a --CO-- radical when X represents a HalCH.sub.2 -- radical, Z being a C.sub.1 -C.sub.4 alkyl radical and Hal a halogen atom.This laevorotatory enantiomer has been found to have significantly higher protective activity against hypoxia and ischemia than the corresponding racemate.
    Type: Grant
    Filed: February 16, 1989
    Date of Patent: July 24, 1990
    Assignee: U C B Societe Anonyme
    Inventors: Jean Gobert, Jean-Pierre Geerts, Guy Bodson
  • Patent number: 4837224
    Abstract: (R)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide, its preparation and pharmaceutical compositions containing the same. It can be prepared either by reacting (R)-alpha-ethyl-2-oxo-1-pyrrolidineactic acid successively with an alkyl haloformate and with ammonia, or, by cyclizing an (R)-2-amino-butanamide of the formula X--CH.sub.2 CH.sub.2 --Y--NHCH (C.sub.2 H.sub.5)CONH.sub.2 wherein Y is a --CH.sub.2 --radical when X represents a ZOOC--radical and Y is a --CO--radical when X represents a HalCH.sub.2 --radical, Z being a C.sub.1 -C.sub.4 alkyl radical and Hal a halogen atom.This dextrorotatory enantiomer has been found to have significantly higher mnemic activity and lower toxicity than the corresponding racemate.
    Type: Grant
    Filed: March 12, 1987
    Date of Patent: June 6, 1989
    Assignee: UCB Societe Anonyme
    Inventors: Jean Gobert, Corneliu Giurgea, Jean-Pierre Geerts, Guy Bodson
  • Patent number: 4696943
    Abstract: (S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide, its preparation and pharmaceutical compositions containing the same. It can be prepared either by reacting (S)-alpha-ethyl-2-oxo-1-pyrrolidineacetic acid successively with an alkyl haloformate and with ammonia, or, by cyclizing an (S)-2-aminobutanamide of the formula X--CH.sub.2 CH.sub.2 --Y--NHCH(C.sub.2 H.sub.5)CONH.sub.2 wherein Y is a --CH.sub.2 -- radical when X represents a ZOOC-- radical and Y is a --CO-- radical when X represents a HalCH.sub.2 -- radical, Z being a C.sub.1 -C.sub.4 alkyl radical and Hal a halogen atom.This laevorotatory enantiomer has been found to have significantly higher protective activity against hypoxia and ischemia than the corresponding racemate.
    Type: Grant
    Filed: May 14, 1985
    Date of Patent: September 29, 1987
    Assignee: U C B Societe Anonyme
    Inventors: Jean Gobert, Jean-Pierre Geerts, Guy Bodson
  • Patent number: 4696942
    Abstract: (R)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide, its preparation and pharmaceutical compositions containing the same. It can be prepared either by reacting (R)-alpha-ethyl-2-oxo-1-pyrrolidineacetic acid successively with an alkyl haloformate and with ammonia, or, by cyclizing an (R)-2-amino-butanamide of the formula X--CH.sub.2 CH.sub.2 --Y--NHCH(C.sub.2 H.sub.5)CONH.sub.2 wherein Y is a --CH.sub.2 -- radical when X represents a ZOOC-- radical and Y is a --CO-- radical when X represents a HalCH.sub.2 -- radical, Z being a C.sub.1 -C.sub.4 alkyl radical and Hal a halogen atom. This dextrorotatory enantiomer has been found to have significantly higher mnemic activity and lower toxicity than the corresponding racemate.
    Type: Grant
    Filed: May 14, 1985
    Date of Patent: September 29, 1987
    Assignee: UCB Societe Anonyme
    Inventors: Jean Gobert, Corneliu Giurgea, Jean-Pierre Geerts, Guy Bodson
  • Patent number: 4036686
    Abstract: Apparatus for visually examining the fuel rods of an assembly of fuel rods immersed in the tank of a nuclear reactor or in a deactivation tank, comprises an endoscope including a prism and an optical system of stabilized glass, and at least one arm supporting a mirror facing the prism and inclined relative to the plane defined by the axis of the tube of the endoscope and the arm, the thickness of the arm-mirror assembly being less than the free space between the rods of the assembly. In use the apparatus is mounted on a system of carriages which enable the apparatus to move in three perpendicular directions, the carriages being associated with rotatable means for supporting an assembly of rods to be examined.
    Type: Grant
    Filed: January 7, 1976
    Date of Patent: July 19, 1977
    Assignees: Societe Franco-Americaine de Constructions Atomiques-Framatome, Bodson, S.A.
    Inventors: Jean-Claude Weilbacher, Guy Bodson