Abstract: The invention relates to a composition intended for administration by the oral or topical route and comprising, in a physiologically acceptable medium, DHEA and/or a chemical or biological precursor or derivative of the latter, in combination with at least one NO-synthase inhibitor. This composition can be used for cosmetic purposes, for preventing or treating irritation of the skin and/or sensitive skin and/or for signs of cutaneous aging. In an alternative form, it can be used for treating the scalp and/or hair or as reducing composition. The NO-synthase inhibitor can be chosen in particular from: lipochroman-6, a grape extract, an olive tree extract, a Gingko biloba extract or epicatechin.

Abstract: The invention relates to a composition intended for administration by the oral or topical route and comprising, in a physiologically acceptable medium, DHEA and/or a chemical or biological precursor or derivative of the latter, in combination with at least one NO-synthase inhibitor.

Abstract: The present invention relates to the cosmetic use of 3&bgr;-acetoxy-7-oxo-DHEA to improve the appearance of keratin materials, with the exception of the treatment of wrinkles and fine lines, dry skin and dermatitis. This use is intended in particular for preventing or treating the loss of firmness of the skin and/or a dull complexion and/or dilation of the pores and/or skin or hair pigmentation disorders and/or hyperseborrhea and/or hyperseborrhea-related imperfections and/or sensitive skin and/or dandruff and/or hair loss and/or baldness.