Abstract: The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.

Abstract: Presented herein are pre-operative surgical planning techniques that enable a user to optimize placement of an implantable component of an implantable medical device in/within the body of a recipient. In particular, a computing device/system is configured to obtain anatomical data associated with the part body of the recipient in which the implantable component is to be implanted. The computing system is configured to analyze the recipient anatomical data to determine one or more suggested implantable placements for the implantable component. The computing device may be configured to predict, at least based on the recipient anatomical data, an estimated outcome for the recipient with the implantable component implanted at a suggested implantable placement.

Abstract: An apparatus, including an implantable portion of a hearing prosthesis, wherein the apparatus is configured to at least partially cancel a signal in the implantable portion, the signal resulting from an external magnetic field generated external to a recipient of the hearing prosthesis. In an exemplary embodiment, the signal is a signal generated by the external magnetic field interacting with an electrical lead extending between a stimulation output device of the prosthesis and a stimulator and/or receiver of the implantable portion.