Patents by Inventor Guy G. Hoffman

Guy G. Hoffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mammalian tolloid-like gene and protein
    Publication number: 20020048565
    Abstract: A mammalian gene encoding a tolloid-like protein distinct from human or murine BMP-1/mTld is presented. The gene is similar in structure to members of the BMP-1 family of genes, but maps to a distinct location and encodes a distinct protein. The protein encoded by the gene can be used to screen putative therapeutic agents in an ongoing effort to inhibit activity of the BMP-1 family of genes to prevent scarring, fibrosis, and the like.
    Type: Application
    Filed: August 29, 2001
    Publication date: April 25, 2002
    Inventors: Daniel S. Greenspan, Kazuhiko Takahara, Guy G. Hoffman
  • Mammalian tolloid-like gene and protein
    Patent number: 6297011
    Abstract: A mammalian gene encoding a tolloid-like protein distinct from human or murine BMP-1/mTld is presented. The gene is similar in structure to members of the BMP-1 family of genes, but maps to a distinct location and encodes a distinct protein. The protein encoded by the gene can be used to screen putative therapeutic agents in an ongoing effort to inhibit activity of the BMP-1 family of genes to prevent scarring, fibrosis, and the like.
    Type: Grant
    Filed: February 1, 1999
    Date of Patent: October 2, 2001
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Daniel S. Greenspan, Kazuhiko Takahara, Guy G. Hoffman
  • Mammalian tolloid-like gene and protein
    Patent number: 5981717
    Abstract: A mammalian gene encoding a tolloid-like protein distinct from human or murine BMP-1/mTld is presented. The gene is similar in structure to members of the BMP-1 family of genes, but maps to a distinct location and encodes a distinct protein. The protein encoded by the gene can be used to screen putative therapeutic agents in an ongoing effort to inhibit activity of the BMP-1 family of genes to prevent scarring, fibrosis, and the like.
    Type: Grant
    Filed: February 10, 1998
    Date of Patent: November 9, 1999
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Daniel S. Greenspan, Kazuhiko Takahara, Guy G. Hoffman
  • Mammalian tolloid-like gene and protein
    Patent number: 5939321
    Abstract: A mammalian gene encoding a tolloid-like protein distinct from human or murine BMP-1/mTld is presented. The gene is similar in structure to members of the BMP-1 family of genes, but maps to a distinct location and encodes a distinct protein. The protein encoded by the gene can be used to screen putative therapeutic agents in an ongoing effort to inhibit activity of the BMP-1 family of genes to prevent scarring, fibrosis, and the like.
    Type: Grant
    Filed: May 30, 1997
    Date of Patent: August 17, 1999
    Assignee: Wisconsin Alumni Research Foundatiion
    Inventors: Daniel S. Greenspan, Kazuhiko Takahara, Guy G. Hoffman
  • Recombinant vector having a Streptomyces achromogenes DNA sequence useful for gene amplification
    Patent number: 5240858
    Abstract: An improved means for amplifying DNA sequences is disclosed. The invention provides a means for creating tandemly repeated gene sequences. One attaches a selected foreign gene sequence in a S. achromogenes fragment and then exposes the recombinant segment to antibiotic challenge. Temperature sensitive plasmids or other curable vectors can be used to assist in the amplification and the positioning of the resulting gene directly in chromosomal host DNA.
    Type: Grant
    Filed: January 8, 1991
    Date of Patent: August 31, 1993
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Ulfert Hornemann, Guy G. Hoffman, Christopher J. Otto