Patents by Inventor Guy Heger

Guy Heger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240382779
    Abstract: A method for treating a tumor, comprising identifying a tumor as a colorectal cancer tumor and implanting in the tumor identified as a colorectal cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 9.2 MBq hour, per centimeter length.
    Type: Application
    Filed: July 25, 2024
    Publication date: November 21, 2024
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20240382780
    Abstract: A method for treating a tumor, comprising identifying a tumor as a melanoma tumor and implanting in the tumor identified as a melanoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.2 Mega becquerel (MBq) hour and 7.5 MBq hour, per centimeter length.
    Type: Application
    Filed: July 25, 2024
    Publication date: November 21, 2024
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20240374921
    Abstract: A method for treating a tumor, comprising identifying a tumor as a glioblastoma tumor and implanting in the tumor identified as a glioblastoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 6.5 Mega becquerel (MBq) hour and 14.3 MBq hour, per centimeter length.
    Type: Application
    Filed: July 25, 2024
    Publication date: November 14, 2024
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20240374919
    Abstract: A method for treating a cancerous tumor, by implanting in the cancerous tumor at least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon of at least 10 Mega becquerel (MBq) hour, per centimeter length. Optionally, the sources are implanted in an array of sources, each source separated from its neighboring sources in the array by not more than 4.5 millimeters.
    Type: Application
    Filed: July 23, 2024
    Publication date: November 14, 2024
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20240374920
    Abstract: A method for treating a tumor, comprising identifying a tumor as a pancreatic cancer tumor and implanting in the tumor identified as a pancreatic cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 5.6 Mega becquerel (MBq) hour and 11.6 MBq hour, per centimeter length.
    Type: Application
    Filed: July 25, 2024
    Publication date: November 14, 2024
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20240374922
    Abstract: A method for treating a tumor, comprising identifying a tumor as a breast cancer tumor and implanting in the tumor identified as a breast cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 9 MBq hour, per centimeter length.
    Type: Application
    Filed: July 25, 2024
    Publication date: November 14, 2024
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Patent number: 12076582
    Abstract: A method for treating a tumor, comprising identifying a tumor as a colorectal cancer tumor and implanting in the tumor identified as a colorectal cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 9.2 MBq hour, per centimeter length.
    Type: Grant
    Filed: January 9, 2023
    Date of Patent: September 3, 2024
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
  • Patent number: 12076581
    Abstract: A method for treating a tumor, comprising identifying a tumor as a glioblastoma tumor and implanting in the tumor identified as a glioblastoma tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 6.5 Mega becquerel (MBq) hour and 14.3 MBq hour, per centimeter length.
    Type: Grant
    Filed: January 9, 2023
    Date of Patent: September 3, 2024
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
  • Patent number: 12076583
    Abstract: A method for treating a tumor, comprising identifying a tumor as a melanoma tumor and implanting in the tumor identified as a melanoma tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.2 Mega becquerel (MBq) hour and 7.5 MBq hour, per centimeter length.
    Type: Grant
    Filed: January 9, 2023
    Date of Patent: September 3, 2024
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
  • Patent number: 12070620
    Abstract: A method for treating a cancerous tumor, by implanting in the cancerous tumor at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon of at least 10 Mega becquerel (MBq) hour, per centimeter length. Optionally, the sources (21) are implanted in an array (160) of sources (21), each source separated from its neighboring sources (21) in the array by not more than 4.5 millimeters.
    Type: Grant
    Filed: January 9, 2023
    Date of Patent: August 27, 2024
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
  • Patent number: 12070621
    Abstract: A method for treating a tumor, comprising identifying a tumor as a pancreatic cancer tumor and implanting in the tumor identified as a pancreatic cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 5.6 Mega becquerel (MBq) hour and 11.6 MBq hour, per centimeter length.
    Type: Grant
    Filed: January 9, 2023
    Date of Patent: August 27, 2024
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
  • Patent number: 12064643
    Abstract: A method for treating a tumor, comprising identifying a tumor as a breast cancer tumor and implanting in the tumor identified as a breast cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 9 MBq hour, per centimeter length.
    Type: Grant
    Filed: January 9, 2023
    Date of Patent: August 20, 2024
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
  • Patent number: 12042668
    Abstract: A method for treating a tumor, comprising identifying a tumor as a squamous cell carcinoma tumor and implanting in the tumor identified as a squamous cell carcinoma tumor at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 8.6 MBq hour, per centimeter length.
    Type: Grant
    Filed: January 9, 2023
    Date of Patent: July 23, 2024
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20240198132
    Abstract: A method for treating a tumor, comprising identifying a tumor as a prostate cancer tumor and implanting in the tumor identified as a prostate cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 7 Mega becquerel (MBq) hour and 14.7 MBq hour, per centimeter length. Each DaRT source is separated from an adjacent DaRT source in the array by less than 3.9 millimeters.
    Type: Application
    Filed: February 26, 2024
    Publication date: June 20, 2024
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Patent number: 11964168
    Abstract: A method for treating a tumor, comprising identifying a tumor as a prostate cancer tumor and implanting in the tumor identified as a prostate cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 7 Mega becquerel (MBq) hour and 14.7 MBq hour, per centimeter length.
    Type: Grant
    Filed: January 9, 2023
    Date of Patent: April 23, 2024
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
  • Patent number: 11666781
    Abstract: Apparatus for planning a diffusing alpha-emitter radiation therapy (DaRT) treatment session. The apparatus includes an output interface and a memory configured with a plurality of tables which provide an accumulated measure of radiation over a specific time period, due to one or more types of DaRT radiotherapy sources which emit daughter radionuclides from the source, for a plurality of different distances and angles relative to the DaRT radiotherapy source. In addition, a processor is configured to receive a description of a layout of a plurality of DaRT radiotherapy sources in a tumor, to calculate a radiation dose distribution in the tumor responsive to the layout, using the tables in the memory, and to output feedback for the treatment responsive to the radiation dose distribution, through the output interface.
    Type: Grant
    Filed: October 10, 2021
    Date of Patent: June 6, 2023
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Itzhak Kelson, Lior Arazi, Amnon Gat, Guy Heger
  • Publication number: 20230158332
    Abstract: A method for treating a tumor, comprising identifying a tumor as a squamous cell carcinoma tumor and implanting in the tumor identified as a squamous cell carcinoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 8.6 MBq hour, per centimeter length.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 25, 2023
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20230158331
    Abstract: A method for treating a tumor, comprising identifying a tumor as a colorectal cancer tumor and implanting in the tumor identified as a colorectal cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 9.2 MBq hour, per centimeter length.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 25, 2023
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20230158330
    Abstract: A method for treating a tumor, comprising identifying a tumor as a breast cancer tumor and implanting in the tumor identified as a breast cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 9 MBq hour, per centimeter length.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 25, 2023
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20230158333
    Abstract: A method for treating a tumor, comprising identifying a tumor as a prostate cancer tumor and implanting in the tumor identified as a prostate cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 7 Mega becquerel (MBq) hour and 14.7 MBq hour, per centimeter length.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 25, 2023
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu