Patents by Inventor Guy Heger
Guy Heger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240382779Abstract: A method for treating a tumor, comprising identifying a tumor as a colorectal cancer tumor and implanting in the tumor identified as a colorectal cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 9.2 MBq hour, per centimeter length.Type: ApplicationFiled: July 25, 2024Publication date: November 21, 2024Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
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Publication number: 20240382780Abstract: A method for treating a tumor, comprising identifying a tumor as a melanoma tumor and implanting in the tumor identified as a melanoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.2 Mega becquerel (MBq) hour and 7.5 MBq hour, per centimeter length.Type: ApplicationFiled: July 25, 2024Publication date: November 21, 2024Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
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Publication number: 20240374921Abstract: A method for treating a tumor, comprising identifying a tumor as a glioblastoma tumor and implanting in the tumor identified as a glioblastoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 6.5 Mega becquerel (MBq) hour and 14.3 MBq hour, per centimeter length.Type: ApplicationFiled: July 25, 2024Publication date: November 14, 2024Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
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Publication number: 20240374919Abstract: A method for treating a cancerous tumor, by implanting in the cancerous tumor at least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon of at least 10 Mega becquerel (MBq) hour, per centimeter length. Optionally, the sources are implanted in an array of sources, each source separated from its neighboring sources in the array by not more than 4.5 millimeters.Type: ApplicationFiled: July 23, 2024Publication date: November 14, 2024Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
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Publication number: 20240374920Abstract: A method for treating a tumor, comprising identifying a tumor as a pancreatic cancer tumor and implanting in the tumor identified as a pancreatic cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 5.6 Mega becquerel (MBq) hour and 11.6 MBq hour, per centimeter length.Type: ApplicationFiled: July 25, 2024Publication date: November 14, 2024Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
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Publication number: 20240374922Abstract: A method for treating a tumor, comprising identifying a tumor as a breast cancer tumor and implanting in the tumor identified as a breast cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 9 MBq hour, per centimeter length.Type: ApplicationFiled: July 25, 2024Publication date: November 14, 2024Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
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Patent number: 12076582Abstract: A method for treating a tumor, comprising identifying a tumor as a colorectal cancer tumor and implanting in the tumor identified as a colorectal cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 9.2 MBq hour, per centimeter length.Type: GrantFiled: January 9, 2023Date of Patent: September 3, 2024Assignee: ALPHA TAU MEDICAL LTD.Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
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Patent number: 12076581Abstract: A method for treating a tumor, comprising identifying a tumor as a glioblastoma tumor and implanting in the tumor identified as a glioblastoma tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 6.5 Mega becquerel (MBq) hour and 14.3 MBq hour, per centimeter length.Type: GrantFiled: January 9, 2023Date of Patent: September 3, 2024Assignee: ALPHA TAU MEDICAL LTD.Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
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Patent number: 12076583Abstract: A method for treating a tumor, comprising identifying a tumor as a melanoma tumor and implanting in the tumor identified as a melanoma tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.2 Mega becquerel (MBq) hour and 7.5 MBq hour, per centimeter length.Type: GrantFiled: January 9, 2023Date of Patent: September 3, 2024Assignee: ALPHA TAU MEDICAL LTD.Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
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Patent number: 12070620Abstract: A method for treating a cancerous tumor, by implanting in the cancerous tumor at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon of at least 10 Mega becquerel (MBq) hour, per centimeter length. Optionally, the sources (21) are implanted in an array (160) of sources (21), each source separated from its neighboring sources (21) in the array by not more than 4.5 millimeters.Type: GrantFiled: January 9, 2023Date of Patent: August 27, 2024Assignee: ALPHA TAU MEDICAL LTD.Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
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Patent number: 12070621Abstract: A method for treating a tumor, comprising identifying a tumor as a pancreatic cancer tumor and implanting in the tumor identified as a pancreatic cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 5.6 Mega becquerel (MBq) hour and 11.6 MBq hour, per centimeter length.Type: GrantFiled: January 9, 2023Date of Patent: August 27, 2024Assignee: ALPHA TAU MEDICAL LTD.Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
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Patent number: 12064643Abstract: A method for treating a tumor, comprising identifying a tumor as a breast cancer tumor and implanting in the tumor identified as a breast cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 9 MBq hour, per centimeter length.Type: GrantFiled: January 9, 2023Date of Patent: August 20, 2024Assignee: ALPHA TAU MEDICAL LTD.Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
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Patent number: 12042668Abstract: A method for treating a tumor, comprising identifying a tumor as a squamous cell carcinoma tumor and implanting in the tumor identified as a squamous cell carcinoma tumor at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 8.6 MBq hour, per centimeter length.Type: GrantFiled: January 9, 2023Date of Patent: July 23, 2024Assignee: ALPHA TAU MEDICAL LTD.Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
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Publication number: 20240198132Abstract: A method for treating a tumor, comprising identifying a tumor as a prostate cancer tumor and implanting in the tumor identified as a prostate cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 7 Mega becquerel (MBq) hour and 14.7 MBq hour, per centimeter length. Each DaRT source is separated from an adjacent DaRT source in the array by less than 3.9 millimeters.Type: ApplicationFiled: February 26, 2024Publication date: June 20, 2024Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
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Patent number: 11964168Abstract: A method for treating a tumor, comprising identifying a tumor as a prostate cancer tumor and implanting in the tumor identified as a prostate cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 7 Mega becquerel (MBq) hour and 14.7 MBq hour, per centimeter length.Type: GrantFiled: January 9, 2023Date of Patent: April 23, 2024Assignee: ALPHA TAU MEDICAL LTD.Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
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Patent number: 11666781Abstract: Apparatus for planning a diffusing alpha-emitter radiation therapy (DaRT) treatment session. The apparatus includes an output interface and a memory configured with a plurality of tables which provide an accumulated measure of radiation over a specific time period, due to one or more types of DaRT radiotherapy sources which emit daughter radionuclides from the source, for a plurality of different distances and angles relative to the DaRT radiotherapy source. In addition, a processor is configured to receive a description of a layout of a plurality of DaRT radiotherapy sources in a tumor, to calculate a radiation dose distribution in the tumor responsive to the layout, using the tables in the memory, and to output feedback for the treatment responsive to the radiation dose distribution, through the output interface.Type: GrantFiled: October 10, 2021Date of Patent: June 6, 2023Assignee: ALPHA TAU MEDICAL LTD.Inventors: Itzhak Kelson, Lior Arazi, Amnon Gat, Guy Heger
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Publication number: 20230158332Abstract: A method for treating a tumor, comprising identifying a tumor as a squamous cell carcinoma tumor and implanting in the tumor identified as a squamous cell carcinoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 8.6 MBq hour, per centimeter length.Type: ApplicationFiled: January 9, 2023Publication date: May 25, 2023Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
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Publication number: 20230158331Abstract: A method for treating a tumor, comprising identifying a tumor as a colorectal cancer tumor and implanting in the tumor identified as a colorectal cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 9.2 MBq hour, per centimeter length.Type: ApplicationFiled: January 9, 2023Publication date: May 25, 2023Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
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Publication number: 20230158330Abstract: A method for treating a tumor, comprising identifying a tumor as a breast cancer tumor and implanting in the tumor identified as a breast cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 9 MBq hour, per centimeter length.Type: ApplicationFiled: January 9, 2023Publication date: May 25, 2023Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
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Publication number: 20230158333Abstract: A method for treating a tumor, comprising identifying a tumor as a prostate cancer tumor and implanting in the tumor identified as a prostate cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 7 Mega becquerel (MBq) hour and 14.7 MBq hour, per centimeter length.Type: ApplicationFiled: January 9, 2023Publication date: May 25, 2023Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu