Patents by Inventor Guy Heger

Guy Heger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11964168
    Abstract: A method for treating a tumor, comprising identifying a tumor as a prostate cancer tumor and implanting in the tumor identified as a prostate cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 7 Mega becquerel (MBq) hour and 14.7 MBq hour, per centimeter length.
    Type: Grant
    Filed: January 9, 2023
    Date of Patent: April 23, 2024
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
  • Patent number: 11666781
    Abstract: Apparatus for planning a diffusing alpha-emitter radiation therapy (DaRT) treatment session. The apparatus includes an output interface and a memory configured with a plurality of tables which provide an accumulated measure of radiation over a specific time period, due to one or more types of DaRT radiotherapy sources which emit daughter radionuclides from the source, for a plurality of different distances and angles relative to the DaRT radiotherapy source. In addition, a processor is configured to receive a description of a layout of a plurality of DaRT radiotherapy sources in a tumor, to calculate a radiation dose distribution in the tumor responsive to the layout, using the tables in the memory, and to output feedback for the treatment responsive to the radiation dose distribution, through the output interface.
    Type: Grant
    Filed: October 10, 2021
    Date of Patent: June 6, 2023
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Itzhak Kelson, Lior Arazi, Amnon Gat, Guy Heger
  • Publication number: 20230158328
    Abstract: A method for treating a cancerous tumor, by implanting in the cancerous tumor at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon of at least 10 Mega becquerel (MBq) hour, per centimeter length. Optionally, the sources (21) are implanted in an array (160) of sources (21), each source separated from its neighboring sources (21) in the array by not more than 4.5 millimeters.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 25, 2023
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20230158333
    Abstract: A method for treating a tumor, comprising identifying a tumor as a prostate cancer tumor and implanting in the tumor identified as a prostate cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 7 Mega becquerel (MBq) hour and 14.7 MBq hour, per centimeter length.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 25, 2023
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20230158329
    Abstract: A method for treating a tumor, comprising identifying a tumor as a glioblastoma tumor and implanting in the tumor identified as a glioblastoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 6.5 Mega becquerel (MBq) hour and 14.3 MBq hour, per centimeter length.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 25, 2023
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20230158332
    Abstract: A method for treating a tumor, comprising identifying a tumor as a squamous cell carcinoma tumor and implanting in the tumor identified as a squamous cell carcinoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 8.6 MBq hour, per centimeter length.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 25, 2023
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20230158330
    Abstract: A method for treating a tumor, comprising identifying a tumor as a breast cancer tumor and implanting in the tumor identified as a breast cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 9 MBq hour, per centimeter length.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 25, 2023
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20230158331
    Abstract: A method for treating a tumor, comprising identifying a tumor as a colorectal cancer tumor and implanting in the tumor identified as a colorectal cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 9.2 MBq hour, per centimeter length.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 25, 2023
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20230143006
    Abstract: A method for treating a tumor, comprising identifying a tumor as a melanoma tumor and implanting in the tumor identified as a melanoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.2 Mega becquerel (MBq) hour and 7.5 MBq hour, per centimeter length.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 11, 2023
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20230142901
    Abstract: A method for treating a tumor, comprising identifying a tumor as a pancreatic cancer tumor and implanting in the tumor identified as a pancreatic cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 5.6 Mega becquerel (MBq) hour and 11.6 MBq hour, per centimeter length.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 11, 2023
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20220401755
    Abstract: A method for treating a tumor, comprising identifying a tumor as a squamous cell carcinoma and implanting in the tumor identified as a squamous cell carcinoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 8 MBq hour, per centimeter length.
    Type: Application
    Filed: June 10, 2021
    Publication date: December 22, 2022
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20220395704
    Abstract: A method for treating a tumor, comprising identifying a tumor as a melanoma tumor and implanting in the tumor identified as a melanoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.4 Mega becquerel (MBq) hour and 8.6 MBq hour, per centimeter length.
    Type: Application
    Filed: June 10, 2021
    Publication date: December 15, 2022
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20220395701
    Abstract: A method for treating a tumor, comprising identifying a tumor as a pancreatic cancer tumor and implanting in the tumor identified as a pancreatic cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 5.6 Mega becquerel (MBq) hour and 9.5 MBq hour, per centimeter length.
    Type: Application
    Filed: June 10, 2021
    Publication date: December 15, 2022
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20220395703
    Abstract: A method for treating a cancerous tumor, by implanting in the cancerous tumor as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon of at least 10 Mega becquerel (MBq) hour, per centimeter length. Optionally, the sources are implanted in an array of sources, each source separated from its neighboring sources in the array by not more than 4.5 millimeters.
    Type: Application
    Filed: June 10, 2021
    Publication date: December 15, 2022
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20220395706
    Abstract: A method for treating a tumor, comprising identifying a tumor as a breast cancer or prostate cancer tumor and implanting in the tumor identified as a breast cancer or prostate cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 8 MBq hour, per centimeter length.
    Type: Application
    Filed: June 10, 2021
    Publication date: December 15, 2022
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20220395700
    Abstract: A method for treating a tumor, comprising identifying a tumor as a colon cancer tumor and implanting in the tumor identified as a colon cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 8.4 MBq hour, per centimeter length.
    Type: Application
    Filed: June 10, 2021
    Publication date: December 15, 2022
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20220395702
    Abstract: A method for treating a tumor, comprising identifying a tumor as a glioblastoma tumor and implanting in the tumor identified as a glioblastoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 8.8 MBq hour, per centimeter length.
    Type: Application
    Filed: June 10, 2021
    Publication date: December 15, 2022
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Dumancic, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20220219012
    Abstract: Apparatus for planning a diffusing alpha-emitter radiation therapy (DaRT) treatment session. The apparatus includes an output interface and a memory configured with a plurality of tables which provide an accumulated measure of radiation over a specific time period, due to one or more types of DaRT radiotherapy sources which emit daughter radionuclides from the source, for a plurality of different distances and angles relative to the DaRT radiotherapy source. In addition, a processor is configured to receive a description of a layout of a plurality of DaRT radiotherapy sources in a tumor, to calculate a radiation dose distribution in the tumor responsive to the layout, using the tables in the memory, and to output feedback for the treatment responsive to the radiation dose distribution, through the output interface.
    Type: Application
    Filed: October 10, 2021
    Publication date: July 14, 2022
    Inventors: Itzhak Kelson, Lior Arazi, Amnon Gat, Guy Heger