Patents by Inventor Guy M. Genin

Guy M. Genin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10401156
    Abstract: A computer-implemented method for determining a quantification of the deformation of the sample is implemented using a computer device in communication with a memory. The method includes receiving, by the computer device, a first image of the sample and a second image of the sample. The method also includes registering the first image to the second image using a warping function. The warping function maps a plurality of pixels in the first image to a plurality of pixels in the second image. A first displacement field for the sample is determined based on the warping function, where the first displacement field includes at least a portion of the warping function. A first quantification of the deformation of the sample is determined based at least in part on the displacement field.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: September 3, 2019
    Assignee: WASHINGTON UNIVERSITY
    Inventors: John J. Boyle, Guy M. Genin, Maiko Kume, Robert B. Pless, Stavros Thomopoulos
  • Publication number: 20190219382
    Abstract: A computer-implemented method for determining a quantification of the deformation of the sample is implemented using a computer device in communication with a memory. The method includes receiving, by the computer device, a first image of the sample and a second image of the sample. The method also includes registering the first image to the second image using a warping function. The warping function maps a plurality of pixels in the first image to a plurality of pixels in the second image. A first displacement field for the sample is determined based on the warping function, where the first displacement field includes at least a portion of the warping function. A first quantification of the deformation of the sample is determined based at least in part on the displacement field.
    Type: Application
    Filed: August 23, 2018
    Publication date: July 18, 2019
    Applicant: WASHINGTON UNIVERSITY
    Inventors: John J. Boyle, Guy M. Genin, Maiko Kume, Robert B. Pless, Stavros Thomopoulos
  • Patent number: 10314574
    Abstract: The field of the disclosure relates generally to sutures and, more specifically, to enhancing suture repair mechanics using adhesives.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: June 11, 2019
    Assignee: Washington University
    Inventors: Stephen W. Linderman, Guy M. Genin, Stavros Thomopoulos
  • Patent number: 10072924
    Abstract: A computer-implemented method for determining a quantification of the deformation of the sample is implemented using a computer device in communication with a memory. The method includes receiving, by the computer device, a first image of the sample and a second image of the sample. The method also includes registering the first image to the second image using a warping function. The warping function maps a plurality of pixels in the first image to a plurality of pixels in the second image. A first displacement field for the sample is determined based on the warping function, where the first displacement field includes at least a portion of the warping function. A first quantification of the deformation of the sample is determined based at least in part on the displacement field.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: September 11, 2018
    Assignee: WASHINGTON UNIVERSITY
    Inventors: John J. Boyle, Guy M. Genin, Maiko Kume, Robert B. Pless, Stavros Thomopoulos
  • Publication number: 20180066936
    Abstract: A computer-implemented method for determining a quantification of the deformation of the sample is implemented using a computer device in communication with a memory. The method includes receiving, by the computer device, a first image of the sample and a second image of the sample. The method also includes registering the first image to the second image using a warping function. The warping function maps a plurality of pixels in the first image to a plurality of pixels in the second image. A first displacement field for the sample is determined based on the warping function, where the first displacement field includes at least a portion of the warping function. A first quantification of the deformation of the sample is determined based at least in part on the displacement field.
    Type: Application
    Filed: March 17, 2015
    Publication date: March 8, 2018
    Inventors: John J. Boyle, Guy M. Genin, Maiko Kume, Robert B. Pless, Stavros Thomopoulos
  • Publication number: 20170089689
    Abstract: A computer-implemented method for determining a quantification of the deformation of the sample is implemented using a computer device in communication with a memory. The method includes receiving, by the computer device, a first image of the sample and a second image of the sample. The method also includes registering the first image to the second image using a warping function. The warping function maps a plurality of pixels in the first image to a plurality of pixels in the second image. A first displacement field for the sample is determined based on the warping function, where the first displacement field includes at least a portion of the warping function. A first quantification of the deformation of the sample is determined based at least in part on the displacement field.
    Type: Application
    Filed: March 17, 2015
    Publication date: March 30, 2017
    Inventors: John J. Boyle, Guy M. Genin, Maiko Kume, Robert B. Pless, Stavros Thomopoulos
  • Publication number: 20160135809
    Abstract: The field of the disclosure relates generally to sutures and, more specifically, to enhancing suture repair mechanics using adhesives.
    Type: Application
    Filed: November 13, 2015
    Publication date: May 19, 2016
    Inventors: Stephen W. Linderman, Guy M. Genin, Stavros Thomopoulos
  • Publication number: 20140377319
    Abstract: Devices and methods of altering protein concentrations in cerebrospinal fluid and/or brain interstitial fluid are disclosed. Devices include a support having at least one protease attached to the support. The device may further include a housing. Devices may be implantable for use in an in vivo active flow system or for use in an in vivo passive system. Devices may also be used in an ex vivo active flow system. Devices may also be used in a passive system to treat cerebrospinal fluid and/or brain interstitial fluid that is withdrawn, or in a passive system that is implanted surgically. Methods include contacting cerebrospinal fluid and/or brain interstitial fluid with a support including at least one protease attached to the support. Proteins contained in the cerebrospinal fluid and/or brain interstitial fluid are cleaved by the protease resulting in the reduction of protein in cerebrospinal fluid and/or brain interstitial fluid.
    Type: Application
    Filed: April 18, 2012
    Publication date: December 25, 2014
    Applicant: WASHINGTON UNIVERSITY
    Inventors: Eric C. Leuthardt, Daniel W. Moran, David Holtzman, Philip Bayly, David Brody, Ralph G. Dacey, Sam Fok, David Jeremiah Garrison, Guy M. Genin, Eriks Lusis, Rohit Pappu, Jingwei Xie, Greg Zipfel
  • Publication number: 20110251515
    Abstract: Observing intracranial physiology includes inserting a bladder at least partially filled with a fluid into a subdural region of interest within a subject, wherein the bladder is coupled in flow communication with a means of indicating a pressure exerted on the bladder within the region of interest. Embodiments also include non-invasively interrogating the means of indicating to determine the pressure exerted on the bladder.
    Type: Application
    Filed: April 8, 2011
    Publication date: October 13, 2011
    Applicant: WASHINGTON UNIVERSITY IN ST. LOUIS
    Inventors: Eric Claude Leuthardt, Benjamin E. Alexander, Samuel F. Wight, Jon T. Willie, David D. Limbrick, Guy M. Genin, Lihong Wang, Shelly Sakiyama-Elbert, David Allen Peters