Abstract: Systems and methods for refining repetitive purchases using historical feedback and contractual data are disclosed. For example, parties to a pharmaceutical purchase transaction typically include one or more of a Group Purchasing Organization (GPO), vendor or manufacturing drug company, wholesaler, and a purchaser, such as a hospital or hospital group. In a typical pharmaceutical purchase transaction, several (possibly inconsistent) agreements can be in place between the parties to the transaction. Disclosed are methods and systems to collect, from a plurality of data sources, information pertaining to negotiated contract prices of pharmaceutical and surgical supplies. Also disclosed is a periodic process to provide purchasing suggestions and receive further feedback from purchasers and suppliers to refine the activities of the purchaser and/or supplier.