Patents by Inventor Guy Oshiro

Guy Oshiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfonyl-substituted bicyclic compounds as modulators of PPAR
    Patent number: 7915253
    Abstract: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
    Type: Grant
    Filed: September 4, 2008
    Date of Patent: March 29, 2011
    Assignee: Kalypsys, Inc
    Inventors: Stewart A. Noble, Guy Oshiro, James W. Malecha, Cunxiang Zhao, Carmen K. Robinson, Sergio G. Duron, Michael Sertic, Andrew K. Lindstrom, Andrew K. Shiau, Christopher D. Bayne, Mehmet Kahraman, Boliang Lou, Steve P. Govek
  • Sulfonyl-substituted bicyclic compounds as modulators of PPAR
    Patent number: 7834004
    Abstract: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
    Type: Grant
    Filed: September 4, 2008
    Date of Patent: November 16, 2010
    Assignee: Kalypsys, Inc
    Inventors: Stewart A. Noble, Guy Oshiro, James W. Malecha, Cunxiang Zhao, Carmen Robinson, Sergio G. Duron, Michael Sertic, Andrew K. Lindstrom, Andrew K. Shiau, Christopher D Bayne, Mehmet Kahraman, Boliang Lou, Steven P. Govek
  • ARYL-SUBSTITUTED HETEROCYCLIC PDE4 INHIBITORS AS ANTI-INFLAMMATORY AGENTS
    Publication number: 20100105729
    Abstract: Disclosed herein are potent and selective aryl-substituted heterocyclic compounds, useful as inhibitors of phosphodiesterase 4 (PDE4), compositions comprising the same, and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of PDE4 activity are also provided, as well as methods for the treatment of inflammatory diseases and other diseases in which PDE4 or one of its isoforms may play a role.
    Type: Application
    Filed: September 20, 2007
    Publication date: April 29, 2010
    Applicant: KALYPSYS, INC.
    Inventors: Steven P. Govek, Guy Oshiro, Stewart A. Noble, James W. Malecha, Andrew K. Shiau
  • HETEROCYCLIC INHIBITORS OF PDE4
    Publication number: 20090275586
    Abstract: The present invention is directed to potent and selective heterocyclic compounds, useful as inhibitors of phosphodiesterase 4 (PDE4), compositions comprising the same, and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of PDE4 activity are also provided, as well as methods for the treatment of inflammatory diseases and other diseases in which PDE4 or one of its isoforms may play a role.
    Type: Application
    Filed: September 20, 2007
    Publication date: November 5, 2009
    Applicant: KALYPSYS, INC.
    Inventors: Steven P. Govek, Guy Oshiro, Stewart A. Noble, James W. Malecha, Andrew K. Shiau
  • SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR
    Publication number: 20090264417
    Abstract: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
    Type: Application
    Filed: September 4, 2008
    Publication date: October 22, 2009
    Applicant: KALYPSYS, INC.
    Inventors: Stewart A. Noble, Guy Oshiro, James W. Malecha, Cunxiang Zhao, Carmen Robinson, Sergio G. Duron, Michael Sertic, Andrew K. Lindstrom, Andrew K. Shiau, Christopher D. Bayne, Mehmet Kahraman, Boliang Lou, Steven P. Govek
  • SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR
    Publication number: 20090227599
    Abstract: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
    Type: Application
    Filed: March 3, 2009
    Publication date: September 10, 2009
    Applicant: KALYPSYS, INC.
    Inventors: Stewart A. Noble, Guy Oshiro, James W. Malecha, Cunxiang Zhao, Sergio G. Duron, Andrew K. Lindstrom, Andrew K. Shiau, Boliang Lou, Steven P. Govek, David J. Thomas
  • Sulfonyl-substituted bicyclic compounds as modulators of PPAR
    Patent number: 7494999
    Abstract: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: February 24, 2009
    Assignee: Kalypsys, Inc
    Inventors: Stewart A. Noble, Guy Oshiro, James W. Malecha, Cunxiang Zhao, Carmen Robinson, Sergio G. Duron, Michael Sertic, Andrew K. Lindstrom, Andrew K. Shiau, Christopher D. Bayne, Mehmet Kahraman, Boliang Lou, Steven P. Govek
  • SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR
    Publication number: 20090029971
    Abstract: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
    Type: Application
    Filed: September 4, 2008
    Publication date: January 29, 2009
    Applicant: KALYPSYS, INC.
    Inventors: Stewart A. Noble, Guy Oshiro, James W. Malecha, Cunxiang Zhao, Carmen Robinson, Sergio G. Duron, Michael Sertic, Andrew K. Lindstrom, Andrew K. Shiau, Christopher D. Bayne, Mehmet Kahraman, Boliang Lou, Steve P. Govek
  • METHODS FOR THE SELECTIVE MODULATION OF PPAR
    Publication number: 20070190079
    Abstract: The present invention relates to methods of selective modulation of peroxisome proliferator activated receptors (PPARs) over G-protein coupled receptor 40 (GPR40), and the use of therapeutically effective amounts of compounds and pharmaceutical compositions which selectively modulate PPAR over GPR40 for the treatment of diseases in patients in need thereof. The methods disclosed herein are exceptionally useful in treating metabolic diseases whilst avoiding certain side effects common to modulators of PPAR previously disclosed in the art.
    Type: Application
    Filed: March 19, 2007
    Publication date: August 16, 2007
    Applicant: KALYPSYS, INC.
    Inventors: Andrew Shiau, Mark Massari, Guy Oshiro, Ayman Kabakibi, James Malecha, Stewart Noble
  • Sulfonyl-substituted bicyclic compounds as modulators of PPAR
    Publication number: 20060205736
    Abstract: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
    Type: Application
    Filed: May 16, 2006
    Publication date: September 14, 2006
    Inventors: Stewart Noble, Guy Oshiro, James Malecha, Cunxiang Zhao, Sergio Duron, Andrew Lindstrom, Andrew Shiau, Boliang Lou, Steven Govek, David Thomas
  • Sulfonyl-substituted bicyclic compounds as modulators of PPAR
    Publication number: 20060167012
    Abstract: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
    Type: Application
    Filed: October 25, 2005
    Publication date: July 27, 2006
    Inventors: Stewart Noble, Guy Oshiro, James Malecha, Cunxiang Zhao, Carmen Robinson, Sergio Duron, Michael Sertic, Andrew Lindstrom, Andrew Shiau, Christopher Bayne, Mehmet Kahraman, Boliang Lou, Steven Govek